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YWHAQ and EFNB1
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
YWHAQ
EFNB1
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
ephrin B1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Nucleus
Cytoplasm
Plasma Membrane
Cell Surface
Membrane
Presynaptic Membrane
Membrane Raft
Synapse
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Protein Binding
Ephrin Receptor Binding
Biological Process
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Neural Crest Cell Migration
Cell Adhesion
Cell-cell Signaling
Nervous System Development
Axon Guidance
Embryonic Pattern Specification
Cell Differentiation
T Cell Costimulation
T Cell Proliferation
Positive Regulation Of T Cell Proliferation
Ephrin Receptor Signaling Pathway
Regulation Of Autophagosome Assembly
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
EPH-Ephrin signaling
EPH-Ephrin signaling
EPHB-mediated forward signaling
EPHB-mediated forward signaling
Ephrin signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells
Drugs
Phenethyl Isothiocyanate
Diseases
Craniosynostosis, including: Pfeiffer syndrome; Apert syndrome; Crouzon syndrome; Jackson-Weiss syndrome; Beare-Stevenson syndrome; Muenke craniosynostosis; Saethre-Chotzen syndrome; Craniosynostosis Boston type; Antley-Bixler syndrome; Carpenter syndrome; Craniofrontonasal dysplasia; Noonan syndrome; Baller-Gerold syndrome
GWAS
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Interacting Genes
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
17 interacting genes:
ANKRD46
CAPN10
CUL3
EPHA3
EPHB1
EPHB2
GRIP1
MYC
NCK2
PICK1
PTPN13
RGS3
SDCBP
SORBS1
SRC
TIAM1
YWHAQ
Entrez ID
10971
1947
HPRD ID
00886
02072
Ensembl ID
ENSG00000134308
ENSG00000090776
Uniprot IDs
P27348
P98172
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
6THG
Enriched GO Terms of Interacting Partners
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Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
Ephrin Receptor Signaling Pathway
Positive Regulation Of Cellular Component Organization
Regulation Of Cellular Component Organization
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Transmembrane-ephrin Receptor Activity
Ephrin Receptor Activity
Dendritic Spine Development
Regulation Of Organelle Organization
Regulation Of Cell Communication
Regulation Of Signaling
Enzyme-linked Receptor Protein Signaling Pathway
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
Regulation Of Cell Junction Assembly
Dendritic Spine Organization
Signaling Receptor Complex Adaptor Activity
Cell Recognition
Protein Tyrosine Kinase Activity
Optic Nerve Morphogenesis
Hindbrain Tangential Cell Migration
Neuron Projection Organization
Postsynapse Organization
Signal Transduction
Cell Migration
Cell-substrate Adhesion
Protein Phosphorylation
Peptidyl-tyrosine Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Activity
Positive Regulation Of Cell Projection Organization
Plasma Membrane
Cytosol
Regulation Of Signal Transduction
Cellular Response To Peptide Hormone Stimulus
Signal Complex Assembly
Phosphorylation
Actin Filament Bundle Assembly
Cell Surface Receptor Signaling Pathway
Cell Motility
Positive Regulation Of Protein Localization To Plasma Membrane
Actin Filament Bundle Organization
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Cellular Component Organization
Cell Projection Organization
Membrane Raft
Axon Guidance Receptor Activity
Fibroblast Apoptotic Process
Positive Regulation Of Protein Localization
Positive Regulation Of Protein Localization To Cell Periphery
Cell Migration In Hindbrain
Positive Regulation Of Protein Localization To Membrane
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Tagcloud (Difference)
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Tagcloud (Intersection)
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