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YWHAQ and ADRB2
Number of citations of the paper that reports this interaction (PubMedID
28298427
)
90
Data Source:
BioGRID
(two hybrid)
YWHAQ
ADRB2
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
adrenoceptor beta 2
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Nucleus
Lysosome
Endosome
Early Endosome
Golgi Apparatus
Plasma Membrane
Cilium
Endosome Membrane
Microtubule Cytoskeleton
Membrane
Apical Plasma Membrane
Clathrin-coated Endocytic Vesicle Membrane
Ciliary Basal Body
Receptor Complex
Intercellular Bridge
Mitotic Spindle
Neuronal Dense Core Vesicle
Molecular Function
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Amyloid-beta Binding
G Protein-coupled Receptor Activity
Adrenergic Receptor Activity
Beta-adrenergic Receptor Activity
Beta2-adrenergic Receptor Activity
Protein Binding
Adenylate Cyclase Binding
Potassium Channel Regulator Activity
Enzyme Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Norepinephrine Binding
Biological Process
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine
Diet Induced Thermogenesis
Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure
Regulation Of Sodium Ion Transport
Transcription By RNA Polymerase II
Receptor-mediated Endocytosis
Smooth Muscle Contraction
Regulation Of Smooth Muscle Contraction
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Endosome To Lysosome Transport
Response To Cold
Positive Regulation Of Bone Mineralization
Heat Generation
Negative Regulation Of Multicellular Organism Growth
Positive Regulation Of MAPK Cascade
Bone Resorption
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Smooth Muscle Contraction
Brown Fat Cell Differentiation
Positive Regulation Of Mini Excitatory Postsynaptic Potential
Adrenergic Receptor Signaling Pathway
Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Blood Vessel Diameter Maintenance
AMPA Selective Glutamate Receptor Signaling Pathway
Positive Regulation Of Cold-induced Thermogenesis
Positive Regulation Of CAMP/PKA Signal Transduction
Positive Regulation Of Autophagosome Maturation
Positive Regulation Of Lipophagy
Cellular Response To Amyloid-beta
Response To Psychosocial Stress
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Adrenoceptors
G alpha (s) signalling events
Ub-specific processing proteases
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Drugs
Phenethyl Isothiocyanate
Spermine
Amphetamine
Betaxolol
Bethanidine
Isoetharine
Cabergoline
Metoprolol
Metoprolol
Olanzapine
Atenolol
Norepinephrine
Timolol
Phenylpropanolamine
Dipivefrin
Sotalol
Carteolol
Nortriptyline
Propranolol
Labetalol
Bisoprolol
Epinephrine
Paroxetine
Trimipramine
Cryptenamine
Orciprenaline
Dobutamine
Pseudoephedrine
Alprenolol
Ritodrine
Ritodrine
Terbutaline
Bitolterol
Phenoxybenzamine
Salmeterol
Pindolol
Formoterol
Salbutamol
Ergoloid mesylate
Isoprenaline
Arbutamine
Amiodarone
Carvedilol
Desipramine
Propafenone
Acebutolol
Nadolol
Levobunolol
Metipranolol
Aripiprazole
Arformoterol
Fenoterol
Pirbuterol
Bevantolol
Penbutolol
Ephedra sinica root
Ephedrine
Mephentermine
Procaterol
Clenbuterol
Bambuterol
Oxprenolol
Putrescine
Spermidine
Celiprolol
Nebivolol
Indacaterol
Bedoradrine
NCX 950
Asenapine
Droxidopa
Bufuralol
Protokylol
(S)-carazolol
Bopindolol
Bupranolol
Befunolol
Olodaterol
Vilanterol
Viloxazine
Arotinolol
Doxofylline
Racepinephrine
Dihydroergocornine
DL-Methylephedrine
Etafedrine
Tulobuterol
Levosalbutamol
Dihydroergocristine
Methoxyphenamine
Diseases
Asthma
GWAS
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Chronic obstructive pulmonary disease (
30804561
33909500
)
Eosinophil percentage of white cells (
32888494
)
FEV1 (
30804560
)
Lung function (FEV1/FVC) (
30804560
)
Lymphocyte percentage of white cells (
27863252
)
Peak expiratory flow (
30804560
)
Systolic blood pressure (
29615537
)
Interacting Genes
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
162 interacting genes:
ABCA7
ADGRG1
ADRB1
ADRB3
AKAP12
AKAP5
ALDOA
ARF4
ARHGAP5
ARHGDIA
ARR3
ARRB1
ARRB2
ARRDC3
ARV1
ATP6V0B
ATP6V0D1
BACE1
BAZ2A
BECN2
BSG
CAV3
CCKBR
CCND2
CD4
CD68
CD81
CD9
CEACAM1
CENPB
CLASP2
CLPTM1L
CNN1
CRYM
CSK
DCAF10
DCLRE1A
DNAJC14
DRD4
EGLN3
EIF2B1
FBXO17
GBP5
GJC2
GMPR2
GNA11
GNA14
GNA15
GNAI1
GNAI2
GNAS
GNAT2
GNB1
GNG2
GNL3L
GOLGB1
GPR37
GPRASP1
GPRC5B
GRB2
GRIA3
GRK1
GRK2
GRK3
GRK4
GRK5
GRK6
GTF2B
HDAC6
HNRNPK
HS2ST1
HTR4
IL1B
IL6R
INSR
KCNE1
KCNJ5
KCNJ6
KCNJ9
KCTD13
KLC1
LRATD2
MAPK8IP2
MBOAT2
MBP
MCAM
MDM2
MFSD12
MFSD2A
MGLL
MITF
MOG
MSR1
NAT14
NCOR2
NEDD4
NHERF1
NHERF2
NIPAL2
NOS1
NPTX1
OBP2A
OPRD1
PLA2G2D
PRDX1
PRKCD
PRNP
PTGDS
PTGER1
PTGES2
RAB14
RAB27A
RAB3A
RACK1
RAN
RAP2C
REL
RGR
RGS10
RGS11
RGS17
RGS2
RGS20
RGS5
RGS8
RGS9
RHOD
RIOX1
RNF41
RTN1
SACS
SENP3
SI
SLC37A1
SLC39A4
SLC52A2
SNCA
SNCG
SPTBN2
SRC
STAT3
STAT4
TCTA
TMCC2
TMEM144
TMEM187
TMEM259
TPTE
TSG101
TSHR
TSPAN7
UCHL1
UST
VAPA
VDAC1
VDAC2
VEGFB
WNK1
YIPF5
YWHAQ
ZNF25
ZNF254
Entrez ID
10971
154
HPRD ID
00886
00187
Ensembl ID
ENSG00000134308
ENSG00000169252
Uniprot IDs
P27348
P07550
X5DQM5
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
1GQ4
2R4R
2R4S
2RH1
3D4S
3KJ6
3NY8
3NY9
3NYA
3P0G
3PDS
3SN6
4GBR
4LDE
4LDL
4LDO
4QKX
5D5A
5D5B
5D6L
5JQH
5X7D
6E67
6KR8
6MXT
6N48
6NI3
6OBA
6PRZ
6PS0
6PS1
6PS2
6PS3
6PS4
6PS5
6PS6
7BZ2
7DHI
7DHR
7XK9
7XKA
8GDZ
8GE1
8GE2
8GE3
8GE4
8GE5
8GE6
8GE7
8GE8
8GE9
8GEA
8GEB
8GEC
8GED
8GEE
8GEF
8GEG
8GEH
8GEI
8GEJ
8GFV
8GFW
8GFX
8GFY
8GFZ
8GG0
8GG1
8GG2
8GG3
8GG4
8GG5
8GG6
8GG7
8GG8
8GG9
8GGA
8GGB
8GGC
8GGE
8GGF
8GGI
8GGJ
8GGK
8GGL
8GGM
8GGN
8GGO
8GGP
8GGQ
8GGR
8GGS
8GGT
8GGU
8GGV
8GGW
8GGX
8GGY
8GGZ
8GH0
8GH1
8JJ8
8JJL
8JJO
8UHB
8UNL
8UNM
8UNN
8UNO
8UNP
8UNQ
8UNR
8UNS
8UNT
8UNU
8UNV
8UNW
8UNX
8UNY
8UNZ
8UO0
8UO1
8UO2
8UO3
8UO4
8W1V
8ZBE
8ZCJ
9CHU
9CHV
9CHX
Enriched GO Terms of Interacting Partners
?
Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
Regulation Of G Protein-coupled Receptor Signaling Pathway
Membrane
G Protein-coupled Receptor Signaling Pathway
Plasma Membrane
GTPase Activity
Receptor Internalization
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Binding
G Protein-coupled Dopamine Receptor Signaling Pathway
Regulation Of Transport
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Signal Transduction
Signal Transduction
G Protein-coupled Receptor Kinase Activity
Regulation Of Biological Quality
Receptor-mediated Endocytosis
Heterotrimeric G-protein Complex
Guanyl Nucleotide Binding
Regulation Of MAPK Cascade
System Process
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Postsynaptic Signal Transduction
G-protein Beta/gamma-subunit Complex Binding
Regulation Of Intracellular Signal Transduction
Beta-adrenergic Receptor Kinase Activity
Negative Regulation Of Signal Transduction
Regulation Of Vesicle-mediated Transport
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Transport
Import Into Cell
Regulation Of Multicellular Organismal Process
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Protein Domain Specific Binding
GTP Binding
Regulation Of Monoatomic Ion Transport
Desensitization Of G Protein-coupled Receptor Signaling Pathway
Beta-2 Adrenergic Receptor Binding
Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of Transport
Acetylcholine Receptor Signaling Pathway
Endocytosis
Heat Generation
Negative Adaptation Of Signaling Pathway
Regulation Of Endocytosis
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Biological Process Involved In Interaction With Host
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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