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YWHAQ and ITGB4
Number of citations of the paper that reports this interaction (PMID
12919677
)
57
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
YWHAQ
ITGB4
Gene Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
integrin, beta 4
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Cytoplasmic Vesicle Membrane
Extracellular Vesicular Exosome
Basement Membrane
Plasma Membrane
Integrin Complex
Basal Plasma Membrane
Cell Surface
Hemidesmosome
Cell Leading Edge
Receptor Complex
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Protein Domain Specific Binding
Protein N-terminus Binding
G-protein Coupled Receptor Binding
Receptor Activity
Protein Binding
Biological Process
Protein Targeting
Apoptotic Process
Small GTPase Mediated Signal Transduction
Substantia Nigra Development
Negative Regulation Of Transcription, DNA-templated
Membrane Organization
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Autophagy
Cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Response To Wounding
Extracellular Matrix Organization
Hemidesmosome Assembly
Cell Junction Assembly
Nail Development
Skin Development
Filopodium Assembly
Mesodermal Cell Differentiation
Digestive Tract Development
Cell Motility
Renal System Development
Amelogenesis
Pathways
Activation of BAD and translocation to mitochondria
Programmed Cell Death
Translocation of GLUT4 to the plasma membrane
Activation of BH3-only proteins
Intrinsic Pathway for Apoptosis
Cell junction organization
Syndecan interactions
Type I hemidesmosome assembly
Collagen formation
Laminin interactions
Non-integrin membrane-ECM interactions
Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Heart rate variability traits (
22174390
)
Protein-Protein Interactions
231 interactors:
AARS2
ABL1
ACSL4
AHCY
AKT1S1
ANXA1
ANXA2
APC
AR
ARHGAP10
ARHGEF16
ATP5A1
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDK17
CDK18
CDKN1A
CDKN1B
CEP170
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
EXO1
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1L1
HADHA
HAT1
HAX1
HDAC4
HDAC5
HDAC7
HIST1H2BG
HIST2H4A
HNRNPA1
HNRNPC
HNRNPF
HNRNPH1
HNRNPK
HSPA1A
HSPA8
HUS1
IARS2
ING1
IQGAP1
IRS2
ITGB4
KCNK15
KCNK3
KCNK9
KIAA1429
KIF1C
KIF23
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LMO7
LYST
MAGOH
MAP3K3
MAP3K5
MARK2
MARK3
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPC4
PABPN1
PAK4
PANK1
PCM1
PDCD6
PDE3A
PDE3B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C2B
PIK3C3
PIK3CB
PKM
PPFIBP1
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
PTPN3
RAF1
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSFA2
SSX2IP
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TP53BP2
TPI1
TPR
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS
WDR61
WDR77
WEE1
WTAP
WWC2
WWP1
YAP1
YWHAE
YWHAG
ZC3H13
ZHX2
23 interactors:
ALOX12
ATXN1
CLCA1
CLCA2
COL17A1
DST
EIF6
ERBB2
ERBB2IP
FYN
GRB2
ITGA6
MET
PLEC
PRKCA
PRKCD
PTK2
SHC1
SREBF2
VIM
YES1
YWHAB
YWHAQ
Entrez ID
10971
3691
HPRD ID
00886
00946
Ensembl ID
ENSG00000134308
ENSG00000132470
Uniprot IDs
B4DMT8
P27348
P16144
PDB IDs
2BTP
1QG3
2YRZ
3F7P
3F7Q
3F7R
3FQ4
3FSO
3H6A
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Metabolic Process
Organelle Organization
Cellular Process
Cellular Response To Organic Substance
Regulation Of Cellular Component Organization
Response To Organic Substance
Response To Stimulus
Positive Regulation Of Cellular Metabolic Process
Developmental Process
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Mitotic Cell Cycle
Regulation Of Metabolic Process
Response To Stress
Cell Cycle
Cellular Response To Stimulus
Mitotic Cell Cycle Process
Death
Regulation Of Apoptotic Process
Programmed Cell Death
Regulation Of Protein Localization
Intracellular Signal Transduction
Apoptotic Process
Cell Cycle Process
Anatomical Structure Development
Cell Death
Regulation Of Cellular Localization
System Development
Multicellular Organismal Development
Regulation Of Establishment Of Protein Localization
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cellular Process
Regulation Of Cell Cycle
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Abiotic Stimulus
Positive Regulation Of Protein Metabolic Process
Intracellular Transport
Regulation Of Signaling
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Regulation Of Phosphorylation
Innate Immune Response
MRNA Metabolic Process
Cellular Localization
Immune System Process
Regulation Of Kinase Activity
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell-cell Adhesion
Fc Receptor Signaling Pathway
Movement Of Cell Or Subcellular Component
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Wounding
Cellular Response To Fibroblast Growth Factor Stimulus
Hemidesmosome Assembly
Response To Fibroblast Growth Factor
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cellular Response To Growth Factor Stimulus
Regulation Of Body Fluid Levels
Response To Growth Factor
Wound Healing
Regulation Of Cell Adhesion
Peptidyl-tyrosine Phosphorylation
Blood Coagulation
Hemostasis
Locomotion
Immune Response-regulating Signaling Pathway
Platelet Activation
Protein Autophosphorylation
Innate Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Chemotaxis
Axon Guidance
Leukocyte Migration
Cell Motility
Positive Regulation Of Signal Transduction
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Apoptotic Process
Cell-substrate Junction Assembly
Regulation Of Cell Activation
Programmed Cell Death
Cell Death
Death
Cellular Response To Peptide Hormone Stimulus
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cellular Response To Organic Substance
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Regulation Of Platelet Aggregation
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud
?
bag1
bcl2l2
bctis
ccna2
comprehend
ctsb
deregulations
fgf1
fosl1
gabrp
gsn
hnepi
id2
il6r
klf5
klk5
map2k7
microdissected
ngfb
ngfr
ontological
pappa
plau
scgb1d2
scgb2a1
serpinb5
serpine1
thbs1
thbs2
Tagcloud (Difference)
?
bag1
bcl2l2
bctis
ccna2
comprehend
ctsb
deregulations
fgf1
fosl1
gabrp
gsn
hnepi
id2
il6r
klf5
klk5
map2k7
microdissected
ngfb
ngfr
ontological
pappa
plau
scgb1d2
scgb2a1
serpinb5
serpine1
thbs1
thbs2
Tagcloud (Intersection)
?