Wiki-Pi
About
Search
People
Updates
Search
CD44 and SPP1
Number of citations of the paper that reports this interaction (PubMedID
10657301
)
0
Data Source:
HPRD
(in vitro)
CD44
SPP1
Description
CD44 molecule (IN blood group)
secreted phosphoprotein 1
Image
GO Annotations
Cellular Component
Extracellular Region
Golgi Apparatus
Cytosol
Plasma Membrane
Microvillus
Focal Adhesion
Cell Surface
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Secretory Granule Membrane
Lamellipodium Membrane
Protein-containing Complex
Macrophage Migration Inhibitory Factor Receptor Complex
Cell Projection
Extracellular Exosome
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Golgi Apparatus
Vesicle
Cell Projection
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Transmembrane Signaling Receptor Activity
Cytokine Receptor Activity
Protein Binding
Collagen Binding
Hyaluronic Acid Binding
Cytokine Activity
Integrin Binding
Protein Binding
Small Molecule Binding
Extracellular Matrix Binding
Biological Process
Inflammatory Response
Cell Adhesion
Cell-matrix Adhesion
Anatomical Structure Morphogenesis
Cell Migration
Cytokine-mediated Signaling Pathway
Hyaluronan Catabolic Process
Positive Regulation Of Heterotypic Cell-cell Adhesion
T Cell Activation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Wound Healing, Spreading Of Cells
Cellular Response To Fibroblast Growth Factor Stimulus
System Development
Cartilage Development
Positive Regulation Of ERK1 And ERK2 Cascade
Monocyte Aggregation
Cell-cell Adhesion
Positive Regulation Of Monocyte Aggregation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Lamellipodium Morphogenesis
Ossification
Osteoblast Differentiation
Androgen Catabolic Process
Cell Adhesion
Signal Transduction
Embryo Implantation
Cell Differentiation
Biomineral Tissue Development
Response To Vitamin D
Response To Macrophage Colony-stimulating Factor
Positive Regulation Of Bone Resorption
Positive Regulation Of DNA-templated Transcription
Decidualization
Response To Steroid Hormone
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Cellular Response To Testosterone Stimulus
Response To 2,3,7,8-tetrachlorodibenzodioxine
Positive Regulation Of Estradiol Secretion
Pathways
Degradation of the extracellular matrix
Cell surface interactions at the vascular wall
Hyaluronan metabolism
Integrin cell surface interactions
Hyaluronan degradation
Neutrophil degranulation
Interferon gamma signaling
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Myoepithelial Cells
Developmental Lineage of Mammary Stem Cells
Degradation of the extracellular matrix
Signaling by PDGF
Integrin cell surface interactions
Integrin cell surface interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
RUNX3 Regulates Immune Response and Cell Migration
Post-translational protein phosphorylation
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes
Drugs
Bivatuzumab
Hyaluronic acid
Diseases
Gastric cancer
GWAS
Bone mineral density (hip) (
30172743
)
Glycemic traits (pleiotropy) (
31021400
)
Intake of sweets (
31005972
)
Response to Vitamin E supplementation (
22437554
)
Systemic lupus erythematosus (
23273568
26502338
27399966
28714469
)
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Total body bone mineral density (
29304378
)
Uterine fibroids (
31649266
)
Vitiligo (
22561518
27723757
)
Blood protein levels (
30072576
)
Dental caries (
23064961
)
Gout (
33832965
)
Urate levels (
31578528
)
Interacting Genes
61 interacting genes:
ABCB1
ABCB5
AKT1
ANK1
ANXA1
ARHGEF1
ARHGEF12
ARNT
CCND2
CD4
CD74
CDK4
CDK6
CDKN2A
CDKN2B
COL14A1
COL1A1
COL1A2
CSK
DMP1
EGFR
EPB41
EPHA2
ERBB4
EZR
FGF2
FGFR4
FN1
FYN
GARS1
GLIS2
GRM1
HBEGF
HMMR
IGFBP3
KDELR2
LATS2
LCK
MADCAM1
MAP2K3
MAP2K5
MDM4
MET
MMP1
MMP7
MMP9
NF2
PDGFRA
PKN1
RAF1
SELE
SPP1
SRC
SRGN
STK11
TGFBR1
TGFBR2
TIAM1
VAV2
VCAN
VHL
97 interacting genes:
ABCF3
ACP5
AFF4
AMOTL2
APOA1
ATP2A2
ATP5PB
BAG6
BRD3
C1RL
CACNG4
CALM1
CC2D1B
CCR8
CD44
CEP162
CHD1
CIMIP5
CISD2
CMTM3
COMMD1
COPS5
CSNK2A1
CSNK2A2
CTNNBL1
CYB5R3
DCX
DNAJB1
DNTTIP2
DRD2
DSEL
EEF1A1
EIF3K
EPAS1
ERBB2
F2
FTH1
GET3
GRIPAP1
HBA2
HMGN1
IGFBP5
ITGA5
ITGA9
ITGAV
ITGB1
ITGB5
KCNIP1
LRRC4
MAP1A
MAP1B
MARCKS
MEOX2
MMP3
MMP7
MPPED1
MRPL23
NACA
NCKAP1
NCS1
NCSTN
PDLIM7
PEMT
PEPD
PLD3
PRKACB
PRKCA
PRKG1
PTGER4
RANBP9
RAPGEF2
RBBP6
RIMS4
RPL13
RPL15
RPL5
RPS13
SEC24C
SGTA
SGTB
SLC22A1
SLC39A6
SNAPIN
SSB
STAU1
STK39
TBC1D8
TMEM168
TMEM30A
TPT1
TTC1
TUBB
UBQLN4
USP42
USP8
ZNF638
ZNF804A
Entrez ID
960
6696
HPRD ID
00115
01325
Ensembl ID
ENSG00000026508
ENSG00000118785
Uniprot IDs
P16070
B7Z351
P10451
Q3LGB0
PDB IDs
1POZ
1UUH
2I83
4PZ3
4PZ4
6TXS
3CXD
3DSF
9EOU
Enriched GO Terms of Interacting Partners
?
Enzyme-linked Receptor Protein Signaling Pathway
Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Signal Transduction
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell Motility
Regulation Of Cell Communication
Regulation Of Signaling
Kinase Activity
Regulation Of Locomotion
Regulation Of Cell Population Proliferation
Regulation Of Developmental Process
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Regulation Of Multicellular Organismal Process
Positive Regulation Of Cell Motility
Positive Regulation Of Signal Transduction
Cell Surface Receptor Signaling Pathway
Protein Tyrosine Kinase Activity
Positive Regulation Of Locomotion
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Cell Differentiation
Intracellular Signal Transduction
Protein Phosphorylation
Animal Organ Development
Developmental Process
Regulation Of Growth
Cellular Developmental Process
Response To Growth Factor
Phosphorylation
Regulation Of Protein Phosphorylation
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Protein Modification Process
ATP Binding
Cellular Response To Growth Factor Stimulus
Regulation Of MAPK Cascade
Regulation Of Multicellular Organismal Development
Regulation Of Cell Differentiation
Regulation Of Phosphorylation
Positive Regulation Of Developmental Process
Cell Migration
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Growth
Regulation Of Cell Growth
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Cell Differentiation
Regulation Of Programmed Cell Death
Cytosol
Modulation Of Chemical Synaptic Transmission
Wound Healing, Spreading Of Cells
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Integrin Complex
Wound Healing, Spreading Of Epidermal Cells
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Biological Quality
Microtubule Associated Complex
Regulation Of Protein Metabolic Process
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Lamellipodium Membrane
Regulation Of Proteolysis
Extracellular Exosome
Integrin-mediated Signaling Pathway
Cell-matrix Adhesion
Negative Regulation Of Proteolysis
Negative Regulation Of Proteasomal Protein Catabolic Process
Integrin Alpha5-beta1 Complex
Cell Adhesion Mediated By Integrin
Integrin Alpha9-beta1 Complex
Integrin Alphav-beta5 Complex
Integrin Alphav-beta1 Complex
Ribosomal Subunit
TRC Complex
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Focal Adhesion
Response To Stress
Endodermal Cell Differentiation
Developmental Process
Negative Regulation Of Protein Catabolic Process
Regulation Of System Process
Protein Kinase CK2 Complex
Alphav-beta3 Integrin-PKCalpha Complex
Dendritic Microtubule
Tail-anchored Membrane Protein Insertion Into ER Membrane
Monoatomic Cation Transport
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Calcium Channel Regulator Activity
Metal Ion Transport
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Synaptic Plasticity
Regulation Of Protein Neddylation
Biological_process
Translation
Dendritic Spine
Cytosolic Ribosome
Ruffle Membrane
Cell-substrate Adhesion
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?