SPP1 and CTNNBL1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SPP1	CTNNBL1
Gene Name		secreted phosphoprotein 1	catenin, beta like 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane
	Molecular Function	Cytokine Activity Protein Binding Extracellular Matrix Binding	Protein Binding Enzyme Binding
	Biological Process	Osteoblast Differentiation Inflammatory Response Cell Adhesion Embryo Implantation Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Biomineral Tissue Development Response To Vitamin D Positive Regulation Of Bone Resorption Decidualization Response To Steroid Hormone Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury	MRNA Splicing, Via Spliceosome Apoptotic Process RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process
Pathways		Signaling by PDGF Integrin cell surface interactions Degradation of the extracellular matrix	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Dental caries ( 23064961)	Bone mineral density ( 17903296)
Protein-Protein Interactions		88 interactors: ABCF3 ACP5 AFF4 AMOTL2 APOA1 ATP2A2 ATP5F1 BAG6 BRD3 C1RL C2orf50 CACNG4 CALM1 CC2D1B CD44 CEP162 CHD1 CISD2 CMTM3 COMMD1 COPS5 CSNK2A1 CSNK2A2 CTNNBL1 CYB5R3 DCX DNAJB1 DNTTIP2 DSEL EEF1A1 EIF3K EPAS1 F2 FTH1 GRIPAP1 HBA2 HMGN1 IGFBP5 ITGA5 ITGA9 ITGAV ITGB1 KCNIP1 LRRC4 MAP1A MAP1B MARCKS MEOX2 MMP3 MMP7 MPPED1 MRPL23 NACA NCKAP1 NCSTN PDLIM7 PEMT PEPD PLD3 PRKACB PRKCA PRKG1 RANBP9 RAPGEF2 RBBP6 RIMS4 RPL13 RPL15 RPL5 RPS13 SEC24C SGTA SLC39A6 SNAPIN SSB STAU1 STK39 TBC1D8 TMEM168 TMEM30A TPT1 TTC1 TUBB UBQLN4 USP42 USP8 ZNF638 ZNF804A	24 interactors: BUD31 CALCOCO1 CATIP CDC5L CDCA7L CREBZF CWC15 HNRNPK IK LDOC1 LUC7L MED4 MEOX2 NGFRAP1 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP U2SURP WBP11 ZCCHC10
Entrez ID		6696	56259
HPRD ID		01325	10850
Ensembl ID		ENSG00000118785	ENSG00000132792
Uniprot IDs		B7Z351 P10451 Q3LGB0	B4DE16 Q8WYA6
PDB IDs		3CXD 3DSF	4HM9 4HNM
Enriched GO Terms of Interacting Partners?		Wound Healing Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Neuron Projection Development Response To Wounding Chemotaxis Locomotion Membrane Organization Cell Projection Organization Axon Development Neuron Development Developmental Process Regulation Of Body Fluid Levels Cellular Localization Extracellular Matrix Organization Regulation Of Proteasomal Protein Catabolic Process Extracellular Structure Organization Chemical Homeostasis Anatomical Structure Development Axon Guidance Axonogenesis System Development Leukocyte Migration Translational Initiation Viral Process Ion Homeostasis Regulation Of Cellular Process Nervous System Development Multicellular Organismal Development Cell Migration Neuron Differentiation Metal Ion Homeostasis Cell Morphogenesis Involved In Neuron Differentiation Translational Elongation Immune System Process Integrin-mediated Signaling Pathway Viral Life Cycle Anatomical Structure Morphogenesis Cell Motility Homeostatic Process Neuron Projection Morphogenesis Heterotypic Cell-cell Adhesion Response To Stress Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Regulation Of Protein Metabolic Process	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Ribonucleoprotein Complex Biogenesis Regulation Of RNA Metabolic Process Cellular Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Nuclear Speck Organization Spliceosomal Complex Assembly Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecular Complex Assembly Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription, DNA-templated Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Splicing Macromolecule Biosynthetic Process Somite Specification Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Transcription From RNA Polymerase II Promoter Cellular Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Metabolic Process
Tagcloud ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose
Tagcloud (Difference) ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose
Tagcloud (Intersection) ?