SPP1 and MAP1A

Number of citations of the paper that reports this interaction (PMID 22779921)
1

Data Source:
BioGRID (two hybrid)

		SPP1	MAP1A
Gene Name		secreted phosphoprotein 1	microtubule-associated protein 1A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Projection Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cytosol Microtubule Microtubule Associated Complex
	Molecular Function	Cytokine Activity Protein Binding Extracellular Matrix Binding	Structural Molecule Activity Protein Binding Microtubule Binding
	Biological Process	Osteoblast Differentiation Inflammatory Response Cell Adhesion Embryo Implantation Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Biomineral Tissue Development Response To Vitamin D Positive Regulation Of Bone Resorption Decidualization Response To Steroid Hormone Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury	Microtubule Cytoskeleton Organization Sensory Perception Of Sound
Pathways		Signaling by PDGF Integrin cell surface interactions Degradation of the extracellular matrix
Drugs			Estramustine
Diseases
GWAS		Dental caries ( 23064961)
Protein-Protein Interactions		88 interactors: ABCF3 ACP5 AFF4 AMOTL2 APOA1 ATP2A2 ATP5F1 BAG6 BRD3 C1RL C2orf50 CACNG4 CALM1 CC2D1B CD44 CEP162 CHD1 CISD2 CMTM3 COMMD1 COPS5 CSNK2A1 CSNK2A2 CTNNBL1 CYB5R3 DCX DNAJB1 DNTTIP2 DSEL EEF1A1 EIF3K EPAS1 F2 FTH1 GRIPAP1 HBA2 HMGN1 IGFBP5 ITGA5 ITGA9 ITGAV ITGB1 KCNIP1 LRRC4 MAP1A MAP1B MARCKS MEOX2 MMP3 MMP7 MPPED1 MRPL23 NACA NCKAP1 NCSTN PDLIM7 PEMT PEPD PLD3 PRKACB PRKCA PRKG1 RANBP9 RAPGEF2 RBBP6 RIMS4 RPL13 RPL15 RPL5 RPS13 SEC24C SGTA SLC39A6 SNAPIN SSB STAU1 STK39 TBC1D8 TMEM168 TMEM30A TPT1 TTC1 TUBB UBQLN4 USP42 USP8 ZNF638 ZNF804A	22 interactors: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 SPP1 TUBA4A TUBB UPF2
Entrez ID		6696	4130
HPRD ID		01325	02549
Ensembl ID		ENSG00000118785	ENSG00000166963
Uniprot IDs		B7Z351 P10451 Q3LGB0	E9PGC8 P78559 Q504X9
PDB IDs		3CXD 3DSF
Enriched GO Terms of Interacting Partners?		Wound Healing Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Neuron Projection Development Response To Wounding Chemotaxis Locomotion Membrane Organization Cell Projection Organization Axon Development Neuron Development Developmental Process Regulation Of Body Fluid Levels Cellular Localization Extracellular Matrix Organization Regulation Of Proteasomal Protein Catabolic Process Extracellular Structure Organization Chemical Homeostasis Anatomical Structure Development Axon Guidance Axonogenesis System Development Leukocyte Migration Translational Initiation Viral Process Ion Homeostasis Regulation Of Cellular Process Nervous System Development Multicellular Organismal Development Cell Migration Neuron Differentiation Metal Ion Homeostasis Cell Morphogenesis Involved In Neuron Differentiation Translational Elongation Immune System Process Integrin-mediated Signaling Pathway Viral Life Cycle Anatomical Structure Morphogenesis Cell Motility Homeostatic Process Neuron Projection Morphogenesis Heterotypic Cell-cell Adhesion Response To Stress Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Regulation Of Protein Metabolic Process	Movement Of Cell Or Subcellular Component Cellular Localization Receptor Localization To Synapse Response To External Stimulus Cytoskeleton Organization Axonogenesis Axon Development Protein Localization To Synapse Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Platelet Activation Cell-cell Signaling Developmental Process Axon Guidance Neuron Projection Morphogenesis Muscle Contraction Blood Coagulation Hemostasis Cell Morphogenesis Involved In Differentiation Muscle System Process Establishment Of Localization In Cell Generation Of Neurons Neuron Projection Development Response To Stimulus Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Locomotion Multicellular Organismal Development Regulation Of Body Fluid Levels Cell Differentiation Synaptic Transmission Wound Healing System Development Nervous System Development Receptor Clustering Transport Neuron Development Cell Development Smooth Muscle Contraction Nucleotide Phosphorylation Establishment Or Maintenance Of Cell Polarity Cell Activation MRNA Export From Nucleus Cytoplasmic Transport Cellular Metal Ion Homeostasis Response To Wounding Cell Morphogenesis Organelle Organization Intracellular Transport
Tagcloud ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose	1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently
Tagcloud (Difference) ?		able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose	1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently
Tagcloud (Intersection) ?