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CD44 and EZR
Number of citations of the paper that reports this interaction (PubMedID
12370738
)
0
Data Source:
HPRD
(in vitro)
CD44
EZR
Description
CD44 molecule (IN blood group)
ezrin
Image
GO Annotations
Cellular Component
Extracellular Region
Golgi Apparatus
Cytosol
Plasma Membrane
Microvillus
Focal Adhesion
Cell Surface
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Secretory Granule Membrane
Lamellipodium Membrane
Protein-containing Complex
Macrophage Migration Inhibitory Factor Receptor Complex
Cell Projection
Extracellular Exosome
Fibrillar Center
Ruffle
Immunological Synapse
Uropod
Extracellular Space
Cytoplasm
Endosome
Cytosol
Cytoskeleton
Actin Filament
Plasma Membrane
Microvillus
Brush Border
Adherens Junction
Focal Adhesion
Cell Cortex
Actin Cytoskeleton
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Filopodium
Cortical Cytoskeleton
Microvillus Membrane
Vesicle
Ruffle Membrane
Protein-containing Complex
Ciliary Basal Body
Cell Projection
Plasma Membrane Raft
Apical Part Of Cell
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Molecular Function
Transmembrane Signaling Receptor Activity
Cytokine Receptor Activity
Protein Binding
Collagen Binding
Hyaluronic Acid Binding
RNA Binding
Actin Binding
Protein Binding
Microtubule Binding
Cytoskeletal Protein Binding
Protein Domain Specific Binding
Protein Kinase A Catalytic Subunit Binding
Protein Kinase A Regulatory Subunit Binding
Identical Protein Binding
S100 Protein Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Actin Filament Binding
Protein Kinase A Binding
ATPase Binding
Disordered Domain Specific Binding
Biological Process
Inflammatory Response
Cell Adhesion
Cell-matrix Adhesion
Anatomical Structure Morphogenesis
Cell Migration
Cytokine-mediated Signaling Pathway
Hyaluronan Catabolic Process
Positive Regulation Of Heterotypic Cell-cell Adhesion
T Cell Activation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Wound Healing, Spreading Of Cells
Cellular Response To Fibroblast Growth Factor Stimulus
System Development
Cartilage Development
Positive Regulation Of ERK1 And ERK2 Cascade
Monocyte Aggregation
Cell-cell Adhesion
Positive Regulation Of Monocyte Aggregation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Lamellipodium Morphogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Intestinal D-glucose Absorption
Sphingosine-1-phosphate Receptor Signaling Pathway
Leukocyte Cell-cell Adhesion
Regulation Of Cell Shape
Positive Regulation Of Gene Expression
Protein Kinase A Signaling
Gland Morphogenesis
Membrane To Membrane Docking
Microvillus Assembly
Actin Cytoskeleton Organization
Astral Microtubule Organization
Protein-containing Complex Localization
Receptor Internalization
Regulation Of Microvillus Length
Negative Regulation Of Interleukin-2 Production
Regulation Of Actin Cytoskeleton Organization
Establishment Or Maintenance Of Apical/basal Cell Polarity
Positive Regulation Of Multicellular Organism Growth
Cortical Microtubule Organization
Establishment Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Protein Catabolic Process
Filopodium Assembly
Negative Regulation Of T Cell Receptor Signaling Pathway
Actin Filament Bundle Assembly
Establishment Of Centrosome Localization
Establishment Of Endothelial Barrier
Negative Regulation Of ERK1 And ERK2 Cascade
Cellular Response To CAMP
Protein Localization To Plasma Membrane
Protein Localization To Cell Cortex
Postsynaptic Actin Cytoskeleton Organization
Regulation Of Non-canonical NF-kappaB Signal Transduction
Regulation Of Organelle Assembly
Terminal Web Assembly
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of P38MAPK Cascade
Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Degradation of the extracellular matrix
Cell surface interactions at the vascular wall
Hyaluronan metabolism
Integrin cell surface interactions
Hyaluronan degradation
Neutrophil degranulation
Interferon gamma signaling
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Myoepithelial Cells
Developmental Lineage of Mammary Stem Cells
Netrin-1 signaling
Recycling pathway of L1
Recycling pathway of L1
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Bivatuzumab
Hyaluronic acid
Diseases
Gastric cancer
GWAS
Bone mineral density (hip) (
30172743
)
Glycemic traits (pleiotropy) (
31021400
)
Intake of sweets (
31005972
)
Response to Vitamin E supplementation (
22437554
)
Systemic lupus erythematosus (
23273568
26502338
27399966
28714469
)
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Total body bone mineral density (
29304378
)
Uterine fibroids (
31649266
)
Vitiligo (
22561518
27723757
)
Bladder cancer (smoking interaction) (
24662972
)
Blond vs. brown/black hair color (
30531825
)
Brown vs. black hair color (
30531825
)
Hair color (
29662168
)
Refractive error (
32231278
)
Interacting Genes
61 interacting genes:
ABCB1
ABCB5
AKT1
ANK1
ANXA1
ARHGEF1
ARHGEF12
ARNT
CCND2
CD4
CD74
CDK4
CDK6
CDKN2A
CDKN2B
COL14A1
COL1A1
COL1A2
CSK
DMP1
EGFR
EPB41
EPHA2
ERBB4
EZR
FGF2
FGFR4
FN1
FYN
GARS1
GLIS2
GRM1
HBEGF
HMMR
IGFBP3
KDELR2
LATS2
LCK
MADCAM1
MAP2K3
MAP2K5
MDM4
MET
MMP1
MMP7
MMP9
NF2
PDGFRA
PKN1
RAF1
SELE
SPP1
SRC
SRGN
STK11
TGFBR1
TGFBR2
TIAM1
VAV2
VCAN
VHL
57 interacting genes:
ACTB
ACTC1
ADORA2B
ADRA1B
ARF6
ARHGDIB
CD44
CDH1
CDK5
CEBPA
CFTR
CLIC5
CTNNB1
DLG1
EGFR
ERBB3
FAS
FASLG
GZMM
ICAM1
ICAM2
ICAM3
IQGAP1
L1CAM
LCK
MDM2
MME
MPP3
MSN
NF2
NHERF1
NHERF2
PALLD
PIK3R1
PRKAR2A
PRKCA
PTK2
PTPRC
RDX
ROCK1
RSPH1
S100P
SCYL3
SDC2
SELL
SELP
SLC26A4-AS1
SPN
SUMO2
TBC1D10A
TMEM8B
TSC1
USP1
VCAM1
VPS11
WFDC1
WWOX
Entrez ID
960
7430
HPRD ID
00115
00475
Ensembl ID
ENSG00000026508
ENSG00000092820
Uniprot IDs
P16070
P15311
PDB IDs
1POZ
1UUH
2I83
4PZ3
4PZ4
6TXS
1NI2
4RM8
4RM9
4RMA
7T1K
7T1L
Enriched GO Terms of Interacting Partners
?
Enzyme-linked Receptor Protein Signaling Pathway
Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Signal Transduction
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cell Motility
Regulation Of Cell Communication
Regulation Of Signaling
Kinase Activity
Regulation Of Locomotion
Regulation Of Cell Population Proliferation
Regulation Of Developmental Process
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Regulation Of Multicellular Organismal Process
Positive Regulation Of Cell Motility
Positive Regulation Of Signal Transduction
Cell Surface Receptor Signaling Pathway
Protein Tyrosine Kinase Activity
Positive Regulation Of Locomotion
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Cell Differentiation
Intracellular Signal Transduction
Protein Phosphorylation
Animal Organ Development
Developmental Process
Regulation Of Growth
Cellular Developmental Process
Response To Growth Factor
Phosphorylation
Regulation Of Protein Phosphorylation
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Protein Modification Process
ATP Binding
Cellular Response To Growth Factor Stimulus
Regulation Of MAPK Cascade
Regulation Of Multicellular Organismal Development
Regulation Of Cell Differentiation
Regulation Of Phosphorylation
Positive Regulation Of Developmental Process
Cell Migration
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Growth
Regulation Of Cell Growth
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Cell Differentiation
Regulation Of Programmed Cell Death
Plasma Membrane
Cell Adhesion
Cell-cell Adhesion
Focal Adhesion
Leukocyte Cell-cell Adhesion
Cell Migration
Cell Motility
Microvillus
Regulation Of Intracellular Signal Transduction
Lamellipodium
Extracellular Exosome
Membrane
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Cell Adhesion
Membrane To Membrane Docking
Regulation Of MAPK Cascade
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Leukocyte Tethering Or Rolling
Regulation Of Multicellular Organismal Process
Response To Growth Factor
Positive Regulation Of Transport
Regulation Of Cell-cell Adhesion
Filopodium
Regulation Of Developmental Process
Regulation Of Cell Migration
Cell Projection
Regulation Of Signal Transduction
Leukocyte Adhesion To Vascular Endothelial Cell
Regulation Of Cellular Localization
Regulation Of Apoptotic Process
Positive Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Membrane Docking
Cell Surface
Cellular Developmental Process
Regulation Of Vesicle-mediated Transport
Regulation Of Cell Motility
Regulation Of Programmed Cell Death
Apical Plasma Membrane
Integrin Binding
Developmental Process
Regulation Of Locomotion
Cell-substrate Adhesion
T Cell Activation
Cell-matrix Adhesion
Ruffle
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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