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UBE2U and TRIM63
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
UBE2U
TRIM63
Gene Name
ubiquitin-conjugating enzyme E2U (putative)
tripartite motif containing 63, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Cytoplasm
HULC Complex
Nucleus
Cytoplasm
Microtubule
Z Disc
M Band
Molecular Function
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Signal Transducer Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Titin Binding
Biological Process
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Muscle Contraction
Signal Transduction
Regulation Of Gene Expression
Skeletal Muscle Atrophy
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Interleukin-1
Cellular Response To Dexamethasone Stimulus
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
66 interactors:
ANAPC11
BARD1
BFAR
CADPS2
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
VPS11
VPS41
ZSWIM2
87 interactors:
ACTA1
AK1
AKR7A2
ALDOA
ANKRD1
APP
ATP5B
ATXN3
ATXN3L
BAP1
CKB
CKM
DCAF6
DES
EEF1G
EHHADH
EIF3E
ENO3
ESPL1
FHL2
FLNC
GFM1
GMEB1
HIBADH
JOSD1
LMCD1
MRPL19
MRPL41
MYBPC1
MYBPC3
MYL2
MYOT
MYOZ1
NDUFA1
NEB
NEBL
NOMO1
NRAP
OTUB1
OTUB2
PDHB
PDK4
PIAS1
PIAS2
PIAS3
PKM
PSMD4
PYGM
SENP2
SENP3
SQSTM1
SRF
STAM
SUMO2
TCAP
TNNC1
TNNI1
TNNI2
TNNI3
TNNT1
TNNT3
TRIM54
TRIM55
TTN
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2I
UBE2J1
UBE2U
UCHL1
UCHL3
UCHL5
UQCRC1
USP13
USP15
USP2
USP21
USP28
USP33
USP4
USP5
USP7
USP8
UXT
YOD1
Entrez ID
148581
84676
HPRD ID
14599
05843
Ensembl ID
ENSG00000177414
ENSG00000158022
Uniprot IDs
Q5VVX9
B4DN95
Q969Q1
PDB IDs
1YRV
2D8U
3DDT
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Protein Metabolic Process
Regulation Of Viral Release From Host Cell
Protein Polyubiquitination
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Viral Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Catabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Innate Immune Response
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Macromolecule Catabolic Process
Regulation Of Protein Stability
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Gene Expression
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Histone H2A Monoubiquitination
Regulation Of Gene Expression
Histone H2A Ubiquitination
Histone H2A-K119 Monoubiquitination
Immune Response
Regulation Of Intracellular Transport
Cellular Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Defense Response
Interferon-gamma-mediated Signaling Pathway
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Histone Monoubiquitination
Negative Regulation Of Cellular Metabolic Process
Regulation Of Viral Entry Into Host Cell
Response To Stress
Negative Regulation Of Viral Transcription
Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Cellular Response To Interferon-gamma
Protein Destabilization
Regulation Of Signal Transduction
Protein Modification By Small Protein Removal
Muscle Filament Sliding
Actin-myosin Filament Sliding
Protein Deubiquitination
Actin-mediated Cell Contraction
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Actin Filament-based Movement
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Proteolysis
Muscle Contraction
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Muscle System Process
Regulation Of Protein Catabolic Process
Actin Filament-based Process
Protein K63-linked Deubiquitination
Striated Muscle Cell Development
Striated Muscle Contraction
Muscle Cell Development
Muscle Structure Development
Myofibril Assembly
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Proteolysis
Cardiac Muscle Tissue Morphogenesis
Striated Muscle Cell Differentiation
Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Muscle Organ Morphogenesis
Actomyosin Structure Organization
Protein Sumoylation
Protein Metabolic Process
Striated Muscle Tissue Development
Muscle Cell Differentiation
Muscle Tissue Development
Regulation Of Muscle Contraction
Protein Modification By Small Protein Conjugation
Muscle Organ Development
Heart Morphogenesis
Regulation Of Cellular Protein Metabolic Process
Cardiac Myofibril Assembly
Muscle Fiber Development
Monoubiquitinated Protein Deubiquitination
Tagcloud
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Difference)
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Intersection)
?