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TRIM63 and ATXN3L
Number of citations of the paper that reports this interaction (PMID
22626734
)
2
Data Source:
BioGRID
(enzymatic study)
TRIM63
ATXN3L
Gene Name
tripartite motif containing 63, E3 ubiquitin protein ligase
ataxin 3-like
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Microtubule
Z Disc
M Band
Mitochondrial Matrix
Mitochondrial Membrane
Nuclear Inclusion Body
Molecular Function
Ubiquitin-protein Transferase Activity
Signal Transducer Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Titin Binding
RNA Polymerase II Regulatory Region DNA Binding
Histone Deacetylase Activity
Ubiquitin-specific Protease Activity
Omega Peptidase Activity
Ubiquitin Protein Ligase Binding
Biological Process
Muscle Contraction
Signal Transduction
Regulation Of Gene Expression
Skeletal Muscle Atrophy
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Interleukin-1
Cellular Response To Dexamethasone Stimulus
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Misfolded Or Incompletely Synthesized Protein Catabolic Process
Protein Deubiquitination
Cellular Response To Heat
Monoubiquitinated Protein Deubiquitination
Exploration Behavior
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Histone H3 Deacetylation
Cellular Response To Misfolded Protein
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
87 interactors:
ACTA1
AK1
AKR7A2
ALDOA
ANKRD1
APP
ATP5B
ATXN3
ATXN3L
BAP1
CKB
CKM
DCAF6
DES
EEF1G
EHHADH
EIF3E
ENO3
ESPL1
FHL2
FLNC
GFM1
GMEB1
HIBADH
JOSD1
LMCD1
MRPL19
MRPL41
MYBPC1
MYBPC3
MYL2
MYOT
MYOZ1
NDUFA1
NEB
NEBL
NOMO1
NRAP
OTUB1
OTUB2
PDHB
PDK4
PIAS1
PIAS2
PIAS3
PKM
PSMD4
PYGM
SENP2
SENP3
SQSTM1
SRF
STAM
SUMO2
TCAP
TNNC1
TNNI1
TNNI2
TNNI3
TNNT1
TNNT3
TRIM54
TRIM55
TTN
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2I
UBE2J1
UBE2U
UCHL1
UCHL3
UCHL5
UQCRC1
USP13
USP15
USP2
USP21
USP28
USP33
USP4
USP5
USP7
USP8
UXT
YOD1
6 interactors:
PJA1
RFFL
TRIM54
TRIM55
TRIM63
USP28
Entrez ID
84676
92552
HPRD ID
05843
19697
Ensembl ID
ENSG00000158022
ENSG00000123594
Uniprot IDs
B4DN95
Q969Q1
B4DYC7
Q9H3M9
PDB IDs
2D8U
3DDT
3O65
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Removal
Muscle Filament Sliding
Actin-myosin Filament Sliding
Protein Deubiquitination
Actin-mediated Cell Contraction
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Actin Filament-based Movement
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Proteolysis
Muscle Contraction
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Muscle System Process
Regulation Of Protein Catabolic Process
Actin Filament-based Process
Protein K63-linked Deubiquitination
Striated Muscle Cell Development
Striated Muscle Contraction
Muscle Cell Development
Muscle Structure Development
Myofibril Assembly
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Proteolysis
Cardiac Muscle Tissue Morphogenesis
Striated Muscle Cell Differentiation
Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Muscle Organ Morphogenesis
Actomyosin Structure Organization
Protein Sumoylation
Protein Metabolic Process
Striated Muscle Tissue Development
Muscle Cell Differentiation
Muscle Tissue Development
Regulation Of Muscle Contraction
Protein Modification By Small Protein Conjugation
Muscle Organ Development
Heart Morphogenesis
Regulation Of Cellular Protein Metabolic Process
Cardiac Myofibril Assembly
Muscle Fiber Development
Monoubiquitinated Protein Deubiquitination
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Catabolic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
Cellular Macromolecule Catabolic Process
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Skeletal Muscle Atrophy
Striated Muscle Atrophy
Muscle Atrophy
Negative Regulation Of Execution Phase Of Apoptosis
Skeletal Muscle Adaptation
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Cellular Protein Modification Process
Proteolysis
Negative Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of Execution Phase Of Apoptosis
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Cellular Response To Dexamethasone Stimulus
Regulation Of Fibroblast Migration
Response To Dexamethasone
Negative Regulation Of Microtubule Depolymerization
Protein K48-linked Ubiquitination
Negative Regulation Of Cytokine-mediated Signaling Pathway
Negative Regulation Of Response To Cytokine Stimulus
Regulation Of Proteolysis
Response To Electrical Stimulus
Regulation Of Signal Transduction By P53 Class Mediator
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Cellular Protein Metabolic Process
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Corticosteroid Stimulus
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of TOR Signaling
Cellular Response To UV
Tagcloud
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Difference)
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Intersection)
?