UBE2U and BFAR

Number of citations of the paper that reports this interaction (PMID 19690564)
33

Data Source:
BioGRID (two hybrid)

		UBE2U	BFAR
Gene Name		ubiquitin-conjugating enzyme E2U (putative)	bifunctional apoptosis regulator
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Cytoplasm HULC Complex	Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Structural Molecule Activity Zinc Ion Binding
	Biological Process	Protein Polyubiquitination DNA Repair Histone Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Apoptotic Process Negative Regulation Of Apoptotic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		66 interactors: ANAPC11 BARD1 BFAR CADPS2 CGRRF1 DTX1 DZIP3 GOLGA2 KAT6A MDM2 MIB1 MIB2 MID2 MKRN3 MUL1 PCGF1 PCGF2 PCGF6 PJA1 PML RBCK1 RNF10 RNF11 RNF113A RNF113B RNF114 RNF125 RNF139 RNF14 RNF144B RNF150 RNF166 RNF17 RNF170 RNF181 RNF2 RNF25 RNF26 RNF41 RNF5 RNFT1 SYVN1 TRAIP TRIM15 TRIM2 TRIM23 TRIM24 TRIM27 TRIM28 TRIM3 TRIM32 TRIM34 TRIM35 TRIM37 TRIM38 TRIM46 TRIM47 TRIM5 TRIM54 TRIM63 TRIM65 TRIM68 TRIM74 VPS11 VPS41 ZSWIM2	11 interactors: BCL2 CASP10 CASP8 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2N UBE2U UBE2W
Entrez ID		148581	51283
HPRD ID		14599	16548
Ensembl ID		ENSG00000177414	ENSG00000103429
Uniprot IDs		Q5VVX9	B4DUT0 Q9NZS9
PDB IDs		1YRV
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Negative Regulation Of Viral Release From Host Cell Protein Metabolic Process Regulation Of Viral Release From Host Cell Protein Polyubiquitination Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Viral Process Protein Catabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Innate Immune Response Proteasomal Protein Catabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Macromolecule Catabolic Process Regulation Of Protein Stability Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Gene Expression Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Histone H2A Monoubiquitination Regulation Of Gene Expression Histone H2A Ubiquitination Histone H2A-K119 Monoubiquitination Immune Response Regulation Of Intracellular Transport Cellular Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Defense Response Interferon-gamma-mediated Signaling Pathway Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Negative Regulation Of Cellular Metabolic Process Regulation Of Viral Entry Into Host Cell Response To Stress Negative Regulation Of Viral Transcription Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Cellular Response To Interferon-gamma Protein Destabilization Regulation Of Signal Transduction	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteolysis Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Innate Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response-regulating Signaling Pathway Cellular Response To Stress Response To Stress Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K11-linked Ubiquitination Protein Metabolic Process Catabolic Process Cellular Response To Oxygen Levels Positive Regulation Of Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune Response Cellular Protein Metabolic Process Defense Response Cellular Protein Modification Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Response To Hypoxia Regulation Of Immune System Process Immune System Process Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Cellular Response To Stimulus
Tagcloud ?			87mg ags alteration arrayed bad bcl2 bcl2l11 bnip3l casp7 cidea cideb combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tnfrsf10b tnfrsf11b tnfrsf1a tnfrsf21 tp73 traf3 uncovering
Tagcloud (Difference) ?			87mg ags alteration arrayed bad bcl2 bcl2l11 bnip3l casp7 cidea cideb combat endows exceptions irrelevant oct4 oct4b1 pluripotent sirnas spliced stream tenfold tnfrsf10b tnfrsf11b tnfrsf1a tnfrsf21 tp73 traf3 uncovering
Tagcloud (Intersection) ?