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UBE2U and PJA1
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
UBE2U
PJA1
Gene Name
ubiquitin-conjugating enzyme E2U (putative)
praja ring finger 1, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Cytoplasm
HULC Complex
Cytoplasm
Molecular Function
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Biological Process
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein Catabolic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
66 interactors:
ANAPC11
BARD1
BFAR
CADPS2
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
VPS11
VPS41
ZSWIM2
36 interactors:
ASCC2
ATP5C1
ATXN3
ATXN3L
EED
ESPL1
EZH2
GSR
HNRNPL
JOSD1
KIF22
MAGED1
MDM2
NDN
NDNL2
OTUB1
OTUB2
RIBC2
SPTBN1
STAM
STAMBP
SUZ12
UBC
UBE2D2
UBE2D3
UBE2L3
UBE2U
UCHL3
UCHL5
USP20
USP28
USP5
USP51
USP7
USP8
ZNF440
Entrez ID
148581
64219
HPRD ID
14599
02335
Ensembl ID
ENSG00000177414
ENSG00000181191
Uniprot IDs
Q5VVX9
Q8NG27
PDB IDs
1YRV
2L0B
Enriched GO Terms of Interacting Partners
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Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Protein Metabolic Process
Regulation Of Viral Release From Host Cell
Protein Polyubiquitination
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Viral Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Catabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Innate Immune Response
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Macromolecule Catabolic Process
Regulation Of Protein Stability
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Gene Expression
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Histone H2A Monoubiquitination
Regulation Of Gene Expression
Histone H2A Ubiquitination
Histone H2A-K119 Monoubiquitination
Immune Response
Regulation Of Intracellular Transport
Cellular Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Defense Response
Interferon-gamma-mediated Signaling Pathway
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Histone Monoubiquitination
Negative Regulation Of Cellular Metabolic Process
Regulation Of Viral Entry Into Host Cell
Response To Stress
Negative Regulation Of Viral Transcription
Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Cellular Response To Interferon-gamma
Protein Destabilization
Regulation Of Signal Transduction
Protein Deubiquitination
Protein Modification By Small Protein Removal
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Proteolysis
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Cellular Protein Modification Process
Regulation Of Protein Catabolic Process
Cellular Protein Metabolic Process
Catabolic Process
Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
DNA Repair
Cellular Response To Stress
Protein K63-linked Deubiquitination
Regulation Of Protein Metabolic Process
Cellular Response To DNA Damage Stimulus
Cellular Metabolic Process
Regulation Of Proteolysis
Nucleobase-containing Compound Metabolic Process
DNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Histone Modification
Cell Cycle Process
Metabolic Process
Nitrogen Compound Metabolic Process
Protein Polyubiquitination
Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Chromosome Organization
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Protein Ubiquitination
Cell Cycle
Cytokinesis
Protein Modification By Small Protein Conjugation
Chromatin Modification
Cellular Response To Oxygen Levels
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Transcription, DNA-templated
Enzyme Linked Receptor Protein Signaling Pathway
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