PJA1 and USP51

Number of citations of the paper that reports this interaction (PMID 22626734)
2

Data Source:
BioGRID (enzymatic study)

		PJA1	USP51
Gene Name		praja ring finger 1, E3 ubiquitin protein ligase	ubiquitin specific peptidase 51
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	SAGA Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Zinc Ion Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Regulation Of Transcription, DNA-templated Histone Deubiquitination Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440	4 interactors: PJA1 USP15 USP21 USP28
Entrez ID		64219	158880
HPRD ID		02335	07167
Ensembl ID		ENSG00000181191	ENSG00000247746
Uniprot IDs		Q8NG27	Q70EK9
PDB IDs		2L0B
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway	Protein Deubiquitination Protein Catabolic Process Protein Modification By Small Protein Removal Regulation Of Proteasomal Protein Catabolic Process Histone Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Proteolysis Cellular Macromolecule Catabolic Process Histone H2B Conserved C-terminal Lysine Deubiquitination Cellular Protein Modification Process Proteolysis Cellular Protein Metabolic Process Monoubiquitinated Protein Deubiquitination Histone Modification Regulation Of Cellular Protein Metabolic Process Pathway-restricted SMAD Protein Phosphorylation Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Protein Metabolic Process Chromatin Modification Chromatin Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To UV Chromosome Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Cellular Response To Light Stimulus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
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