PJA1 and ATP5C1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PJA1	ATP5C1
Gene Name		praja ring finger 1, E3 ubiquitin protein ligase	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	ATPase Activity Transmembrane Transporter Activity Poly(A) RNA Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Oxidative Phosphorylation ATP Biosynthetic Process Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440	23 interactors: APP ATP5A1 ATP5B CA12 CCND3 CCT7 CHMP2B DPP3 EGFR ELOF1 GDPD2 ITIH2 MED15 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTN SERPINA1 ZNF337
Entrez ID		64219	509
HPRD ID		02335	00156
Ensembl ID		ENSG00000181191	ENSG00000165629
Uniprot IDs		Q8NG27	P36542 Q8TAS0
PDB IDs		2L0B
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway	Mitochondrial ATP Synthesis Coupled Proton Transport Respiratory Electron Transport Chain Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Electron Transport Chain ATP Metabolic Process ATP Synthesis Coupled Proton Transport Cellular Respiration ATP Biosynthetic Process Alkanesulfonate Metabolic Process Response To Methanol Purine Nucleoside Metabolic Process Ion Homeostasis Nucleotide Metabolic Process Negative Regulation Of Endopeptidase Activity Learning Or Memory Negative Regulation Of Peptidase Activity ATP Hydrolysis Coupled Proton Transport Synaptic Growth At Neuromuscular Junction Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Response To Triglyceride Astrocyte Activation Platelet Degranulation Purine Ribonucleoside Monophosphate Biosynthetic Process Ossification Positive Regulation Of Cell Cycle Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cognition Ribonucleotide Metabolic Process Nucleoside Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Nucleobase-containing Small Molecule Metabolic Process Purine Nucleotide Metabolic Process Regulation Of ERBB Signaling Pathway Negative Regulation Of Dendritic Spine Morphogenesis Collateral Sprouting In Absence Of Injury Nucleoside Triphosphate Biosynthetic Process Ribose Phosphate Metabolic Process Cell Activation Ribonucleoside Monophosphate Biosynthetic Process Small Molecule Metabolic Process Activation Of Phospholipase A2 Activity Response To Chromate Negative Regulation Of Proteolysis Cellular Metabolic Process Regulation Of Catalytic Activity Nucleobase-containing Compound Metabolic Process Nucleoside Monophosphate Biosynthetic Process Negative Regulation Of Protein Processing Cellular Localization
Tagcloud ?			3xflag compatible created creating ddost deleted dissociated envelope immunolocalization knock mammals persists phosphatases pp1 ppp1ca ppp1cb ppp1cc ppp1cc1 ppp1cc2 reciprocal sbp sedimentation spermatogenesis spermatogenic splice tagged tandem testis ubiquitously
Tagcloud (Difference) ?			3xflag compatible created creating ddost deleted dissociated envelope immunolocalization knock mammals persists phosphatases pp1 ppp1ca ppp1cb ppp1cc ppp1cc1 ppp1cc2 reciprocal sbp sedimentation spermatogenesis spermatogenic splice tagged tandem testis ubiquitously
Tagcloud (Intersection) ?