PJA1 and MAGEB4

Number of citations of the paper that reports this interaction (PubMedID 21461837)
0

Data Source:
BioGRID (enzymatic study)

		PJA1	MAGEB4
Description		praja ring finger ubiquitin ligase 1	MAGE family member B4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 29273807) Platelet count ( 32888494) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		63 interacting genes: ABR ASCC2 ATP5F1C ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 DYRK1A EED ELAC1 ESPL1 EZH2 FGF12 GATD3 GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440	41 interacting genes: AARD ACOT11 ARID3A BLOC1S1 CCDC136 CCDC14 CIMIP2B DVL3 EEF1AKMT3 FAM136A FERD3L FLOT2 FTSJ3 GOLGA6L2 GPATCH2 H2AP HGS IHO1 KANK2 KRT38 LZTS2 MAGEA8 MED21 MESD NEUROD4 PFDN6 PICK1 PJA1 ROCK1 RUNDC3A SH2D1B THOC1 TNR TRAK1 UQCRB USHBP1 USP25 WDR62 YWHAE ZNF341 ZRANB1
Entrez ID		64219	4115
HPRD ID		02335	02150
Ensembl ID		ENSG00000181191	ENSG00000120289
Uniprot IDs		Q8NG27	O15481
PDB IDs		2L0B
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Cysteine-type Deubiquitinase Activity Cysteine-type Peptidase Activity Post-translational Protein Modification Ubiquitin Conjugating Enzyme Activity Proteolysis Protein Modification Process Peptidase Activity Deubiquitinase Activity Cytosol ATP Binding Pronucleus Ubiquitin Binding Protein K48-linked Deubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Chromatin Silencing Complex Protein Polyubiquitination Macromolecule Metabolic Process Facultative Heterochromatin Formation ESC/E(Z) Complex Nucleotide Binding Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Cysteine-type Endopeptidase Activity DNA Repair Regulation Of Proteasomal Protein Catabolic Process Mitotic Cytokinesis Transferase Activity Protein K63-linked Deubiquitination DNA Damage Response Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Hydrolase Activity Protein Modification By Small Protein Conjugation DeNEDDylase Activity Sex Chromatin DNA Metabolic Process Ubiquitin-protein Transferase Activity Cytoskeleton-dependent Cytokinesis Kinase Activity Regulation Of Protein Catabolic Process Protein K11-linked Ubiquitination Negative Regulation Of Intracellular Signal Transduction Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Antibiotic Negative Regulation Of Signal Transduction By P53 Class Mediator
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