PJA1 and HNRNPL

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PJA1	HNRNPL
Gene Name		praja ring finger 1, E3 ubiquitin protein ligase	heterogeneous nuclear ribonucleoprotein L
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Nucleotide Binding RNA Binding Protein Binding Transcription Regulatory Region DNA Binding Poly(A) RNA Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440	16 interactors: APEX1 CSE1L CSNK2A1 FGFR3 HIST3H3 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH NEDD4 PCBP2 PJA1 PTBP1 SUMO4
Entrez ID		64219	3191
HPRD ID		02335	04360
Ensembl ID		ENSG00000181191	ENSG00000104824
Uniprot IDs		Q8NG27	P14866 Q6NTA2
PDB IDs		2L0B	3R27 3TO8
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway	Negative Regulation Of Cellular Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Negative Regulation Of Defense Response To Virus MRNA Processing Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Cellular Metabolic Process MRNA Metabolic Process Positive Regulation Of Protein Catabolic Process Viral Process Negative Regulation Of Type I Interferon Production RNA Processing RNA Metabolic Process Negative Regulation Of Mitotic Nuclear Division Protein Modification By Small Protein Conjugation Protein Catabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Response To Virus Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Transmission Of Virus Development Involved In Symbiotic Interaction Catabolic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Gene Expression Base-excision Repair Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Immune Response Telomere Maintenance Negative Regulation Of Gene Expression Negative Regulation Of Cell Division Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Interleukin-7-mediated Signaling Pathway Oncogene-induced Cell Senescence Regulation Of Defense Response To Virus Negative Regulation Of Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?