PJA1 and KIF22

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PJA1	KIF22
Gene Name		praja ring finger 1, E3 ubiquitin protein ligase	kinesin family member 22
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Gene Ontology Annotations	Cellular Component	Cytoplasm	Kinetochore Chromatin Nucleus Nucleoplasm Cytoplasm Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	DNA Binding Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Protein Ubiquitination Protein Catabolic Process	DNA Repair Microtubule-based Movement Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Metaphase Plate Congression Blood Coagulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS			Red blood cell traits ( 23222517)
Protein-Protein Interactions		36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440	6 interactors: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL
Entrez ID		64219	3835
HPRD ID		02335	04445
Ensembl ID		ENSG00000181191	ENSG00000079616
Uniprot IDs		Q8NG27	B7Z9T5 Q14807
PDB IDs		2L0B	2EDU 3BFN
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud ?			advance amelanotic behaviour colonization doi ezh2 heterogeneity heterogeneous intravital kif2c melanoma motile motility moving notch november oca2 onc online ordinated overlapping pigment polycomb publication repressive singly srf streams suppressing
Tagcloud (Difference) ?			advance amelanotic behaviour colonization doi ezh2 heterogeneity heterogeneous intravital kif2c melanoma motile motility moving notch november oca2 onc online ordinated overlapping pigment polycomb publication repressive singly srf streams suppressing
Tagcloud (Intersection) ?