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RNF2 and UBE2U
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
RNF2
UBE2U
Gene Name
ring finger protein 2
ubiquitin-conjugating enzyme E2U (putative)
Image
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
Nuclear Chromatin
Cytoplasm
HULC Complex
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
RING-like Zinc Finger Domain Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Transcription, DNA-templated
Anterior/posterior Axis Specification
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Oxidative Stress Induced Senescence
Cellular Senescence
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
54 interactors:
ABCB1
AMBRA1
BMI1
CASP3
CASP9
CBX4
CBX6
CBX7
CBX8
HIST1H2AB
HIST2H2AA3
HIST2H2AC
HIST3H3
KAT8
KMT2A
L3MBTL2
MBD1
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PGP
PHB2
PHC1
PSMC4
RING1
RRM1
RYBP
SMURF2
SSX2
TARDBP
TFCP2
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
UBE3A
USP11
USP19
USP7
WASH1
66 interactors:
ANAPC11
BARD1
BFAR
CADPS2
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
VPS11
VPS41
ZSWIM2
Entrez ID
6045
148581
HPRD ID
07028
14599
Ensembl ID
ENSG00000121481
ENSG00000177414
Uniprot IDs
B3KRH1
Q99496
Q5VVX9
PDB IDs
2H0D
3GS2
3H8H
3IXS
3RPG
1YRV
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Cellular Protein Modification Process
Histone Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Protein Catabolic Process
Chromatin Modification
Cellular Macromolecule Catabolic Process
Protein Catabolic Process
Cellular Metabolic Process
Chromatin Organization
Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Transcription, DNA-templated
Chromosome Organization
Histone Modification
RNA Biosynthetic Process
Protein Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Proteolysis
Protein Monoubiquitination
Negative Regulation Of RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Catabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Protein K63-linked Ubiquitination
Macromolecule Biosynthetic Process
Metabolic Process
Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Gene Expression
Regulation Of Metabolic Process
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Protein Metabolic Process
Regulation Of Viral Release From Host Cell
Protein Polyubiquitination
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Viral Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Catabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Innate Immune Response
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Macromolecule Catabolic Process
Regulation Of Protein Stability
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Gene Expression
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Histone H2A Monoubiquitination
Regulation Of Gene Expression
Histone H2A Ubiquitination
Histone H2A-K119 Monoubiquitination
Immune Response
Regulation Of Intracellular Transport
Cellular Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Defense Response
Interferon-gamma-mediated Signaling Pathway
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Histone Monoubiquitination
Negative Regulation Of Cellular Metabolic Process
Regulation Of Viral Entry Into Host Cell
Response To Stress
Negative Regulation Of Viral Transcription
Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Cellular Response To Interferon-gamma
Protein Destabilization
Regulation Of Signal Transduction
Tagcloud
?
aldrich
ambra1
arp2
associates
autophagy
becn1
cul4a
ddb1
e3
elusive
endosomal
impairs
impede
interactor
k48
k63
ligase
linkage
pik3c3
potentiates
scar
sorting
starvation
suppresses
ubiquitinate
ubiquitination
wash
wasp
wiskott
Tagcloud (Difference)
?
aldrich
ambra1
arp2
associates
autophagy
becn1
cul4a
ddb1
e3
elusive
endosomal
impairs
impede
interactor
k48
k63
ligase
linkage
pik3c3
potentiates
scar
sorting
starvation
suppresses
ubiquitinate
ubiquitination
wash
wasp
wiskott
Tagcloud (Intersection)
?