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RNF2 and HIST1H2AB
Number of citations of the paper that reports this interaction (PMID
25355358
)
0
Data Source:
BioGRID
(enzymatic study)
RNF2
HIST1H2AB
Gene Name
ring finger protein 2
histone cluster 1, H2ab
Image
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Euchromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
MLL1 Complex
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
RING-like Zinc Finger Domain Binding
DNA Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Mitotic Cell Cycle
Gastrulation With Mouth Forming Second
Transcription, DNA-templated
Anterior/posterior Axis Specification
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Biological_process
Pathways
Oxidative Stress Induced Senescence
Cellular Senescence
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
54 interactors:
ABCB1
AMBRA1
BMI1
CASP3
CASP9
CBX4
CBX6
CBX7
CBX8
HIST1H2AB
HIST2H2AA3
HIST2H2AC
HIST3H3
KAT8
KMT2A
L3MBTL2
MBD1
OTUD6A
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PGP
PHB2
PHC1
PSMC4
RING1
RRM1
RYBP
SMURF2
SSX2
TARDBP
TFCP2
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2J1
UBE2K
UBE2L3
UBE2U
UBE2V1
UBE2V2
UBE2W
UBE3A
USP11
USP19
USP7
WASH1
9 interactors:
BRCA1
CDK1
CDK2
EP300
ERCC6
KAT2B
RNF2
UHRF1
USP16
Entrez ID
6045
8335
HPRD ID
07028
09105
Ensembl ID
ENSG00000121481
ENSG00000137259
Uniprot IDs
B3KRH1
Q99496
P04908
Q08AJ9
PDB IDs
2H0D
3GS2
3H8H
3IXS
3RPG
2CV5
3A6N
3AFA
3AN2
3AV1
3AV2
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3W96
3W97
3W98
3W99
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Cellular Protein Modification Process
Histone Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Protein Catabolic Process
Chromatin Modification
Cellular Macromolecule Catabolic Process
Protein Catabolic Process
Cellular Metabolic Process
Chromatin Organization
Cellular Protein Metabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Transcription, DNA-templated
Chromosome Organization
Histone Modification
RNA Biosynthetic Process
Protein Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Proteolysis
Protein Monoubiquitination
Negative Regulation Of RNA Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Catabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Protein K63-linked Ubiquitination
Macromolecule Biosynthetic Process
Metabolic Process
Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Gene Expression
Regulation Of Metabolic Process
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Histone Modification
Chromatin Modification
Chromatin Organization
Cell Cycle
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Chromosome Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Macromolecule Biosynthetic Process
Cellular Response To Stress
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
N-terminal Peptidyl-lysine Acetylation
Nucleobase-containing Compound Metabolic Process
Cell Cycle Process
Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organelle Organization
Centrosome Cycle
Cellular Nitrogen Compound Metabolic Process
Cellular Protein Modification Process
DNA Repair
Positive Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Mitotic Cell Cycle
Centrosome Organization
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Microtubule Organizing Center Organization
N-terminal Protein Amino Acid Acetylation
Signal Transduction By P53 Class Mediator
Cellular Protein Metabolic Process
Regulation Of Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Positive Regulation Of Transcription From RNA Polymerase II Promoter
DNA Metabolic Process
Positive Regulation Of DNA Metabolic Process
DNA Damage Checkpoint
Tagcloud
?
aldrich
ambra1
arp2
associates
autophagy
becn1
cul4a
ddb1
e3
elusive
endosomal
impairs
impede
interactor
k48
k63
ligase
linkage
pik3c3
potentiates
scar
sorting
starvation
suppresses
ubiquitinate
ubiquitination
wash
wasp
wiskott
Tagcloud (Difference)
?
aldrich
ambra1
arp2
associates
autophagy
becn1
cul4a
ddb1
e3
elusive
endosomal
impairs
impede
interactor
k48
k63
ligase
linkage
pik3c3
potentiates
scar
sorting
starvation
suppresses
ubiquitinate
ubiquitination
wash
wasp
wiskott
Tagcloud (Intersection)
?