RNF2 and PGP

Number of citations of the paper that reports this interaction (PMID 17088979)
3

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RNF2	PGP
Gene Name		ring finger protein 2	phosphoglycolate phosphatase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Euchromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex MLL1 Complex
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity RING-like Zinc Finger Domain Binding	Magnesium Ion Binding Protein Tyrosine Phosphatase Activity Phosphoglycolate Phosphatase Activity Nucleotide Phosphatase Activity, Acting On Free Nucleotides
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Gastrulation With Mouth Forming Second Transcription, DNA-templated Anterior/posterior Axis Specification Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination	Carbohydrate Metabolic Process Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		54 interactors: ABCB1 AMBRA1 BMI1 CASP3 CASP9 CBX4 CBX6 CBX7 CBX8 HIST1H2AB HIST2H2AA3 HIST2H2AC HIST3H3 KAT8 KMT2A L3MBTL2 MBD1 OTUD6A PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PGP PHB2 PHC1 PSMC4 RING1 RRM1 RYBP SMURF2 SSX2 TARDBP TFCP2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2J1 UBE2K UBE2L3 UBE2U UBE2V1 UBE2V2 UBE2W UBE3A USP11 USP19 USP7 WASH1	2 interactors: LIG4 RNF2
Entrez ID		6045	283871
HPRD ID		07028	19077
Ensembl ID		ENSG00000121481	ENSG00000184207
Uniprot IDs		B3KRH1 Q99496	A6NDG6
PDB IDs		2H0D 3GS2 3H8H 3IXS 3RPG
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Protein K48-linked Ubiquitination Cellular Protein Modification Process Histone Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Protein Catabolic Process Chromatin Modification Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Metabolic Process Chromatin Organization Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Transcription, DNA-templated Chromosome Organization Histone Modification RNA Biosynthetic Process Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Proteolysis Protein Monoubiquitination Negative Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Catabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Protein K63-linked Ubiquitination Macromolecule Biosynthetic Process Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Gene Expression Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression	DNA Ligation Involved In DNA Recombination Histone H2A-K119 Monoubiquitination Lagging Strand Elongation Pro-B Cell Differentiation Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Immunoglobulin V(D)J Recombination DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Histone H2A Monoubiquitination Lymphoid Progenitor Cell Differentiation DNA Ligation Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Histone Monoubiquitination Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Chromosome Organization Isotype Switching Embryo Development V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Histone Ubiquitination Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Cell Cycle Protein Monoubiquitination Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Response To Gamma Radiation Gastrulation With Mouth Forming Second Neuron Apoptotic Process Immunoglobulin Production Positive Regulation Of Fibroblast Proliferation Neuron Death T Cell Differentiation In Thymus Anterior/posterior Axis Specification Somatic Stem Cell Maintenance Nucleotide-excision Repair Regulation Of Fibroblast Proliferation DNA-dependent DNA Replication DNA Biosynthetic Process Axis Specification Cellular Response To Metal Ion Cellular Response To Inorganic Substance Response To Ionizing Radiation
Tagcloud ?		aldrich ambra1 arp2 associates autophagy becn1 cul4a ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott	arac blast capable chemotherapy cr de designed glycoprotein intensive kaplan leukaemia m2 mdr meier mitoxantrone multidrug myelodysplastic novo possibly produces q quinine randomized receive remission reverting successful syndromes threatening
Tagcloud (Difference) ?		aldrich ambra1 arp2 associates autophagy becn1 cul4a ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott	arac blast capable chemotherapy cr de designed glycoprotein intensive kaplan leukaemia m2 mdr meier mitoxantrone multidrug myelodysplastic novo possibly produces q quinine randomized receive remission reverting successful syndromes threatening
Tagcloud (Intersection) ?