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POT1 and GAPDH
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
POT1
GAPDH
Description
protection of telomeres 1
glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Shelterin Complex
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Cytoskeleton
Plasma Membrane
Microtubule Cytoskeleton
Membrane
Nuclear Membrane
Vesicle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
DNA Binding
Protein Binding
Telomerase Inhibitor Activity
DEAD/H-box RNA Helicase Binding
Telomeric DNA Binding
Single-stranded Telomeric DNA Binding
Telomeric D-loop Binding
Telomeric G-quadruplex DNA Binding
G-rich Strand Telomeric DNA Binding
8-hydroxy-2'-deoxyguanosine DNA Binding
G-rich Single-stranded DNA Binding
Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity
Protein Binding
Microtubule Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor
Transferase Activity
Aspartic-type Endopeptidase Inhibitor Activity
Peptidyl-cysteine S-nitrosylase Activity
Identical Protein Binding
NADP Binding
NAD Binding
Disordered Domain Specific Binding
Biological Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of DNA Strand Elongation
Telomeric D-loop Disassembly
Establishment Of Protein Localization To Telomere
Positive Regulation Of Telomeric D-loop Disassembly
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Microtubule Cytoskeleton Organization
Positive Regulation Of Cytokine Production
Immune System Process
Glucose Metabolic Process
Glycolytic Process
Regulation Of Translation
Apoptotic Process
Negative Regulation Of Endopeptidase Activity
Regulation Of Macroautophagy
Negative Regulation Of Translation
Killing Of Cells Of Another Organism
Positive Regulation Of Type I Interferon Production
Peptidyl-cysteine S-trans-nitrosylation
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Innate Immune Response
Protein Stabilization
Defense Response To Fungus
Neuron Apoptotic Process
Killing By Host Of Symbiont Cells
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Type II Interferon
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Glycolysis
Gluconeogenesis
Drugs
NADH
Adenosine-5-Diphosphoribose
Thionicotinamide-Adenine-Dinucleotide
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Xanthinol
Copper
Artenimol
Diseases
GWAS
Chronic lymphocytic leukemia (
24292274
28165464
)
Cutaneous malignant melanoma (
26237428
)
Leukocyte telomere length (
31171785
32109421
)
Refractive error (
32231278
)
Response to selective serotonin reuptake inhibitors and depression (
27622933
)
Telomere length (
33941849
)
Blood protein levels (
30072576
)
Interacting Genes
166 interacting genes:
ACD
ACOT7
ACTB
ACTN4
ACY1
AFAP1L2
AHCY
AHNAK
AIPL1
ALDH1A1
ALDH3A1
AMPD2
ANKMY2
ANXA2
ANXA4
APPL2
ARHGDIA
ARID3B
ARRB1
BAG3
BCAS2
BIN2
C2orf74
CALD1
CAMK1D
CCDC32
CCDC9
CCM2
CFL1
CFL2
CKB
CLIC3
CNST
CORO1A
COX6A2
CPNE3
CPPED1
CRK
CRYGS
CSNK2B
CYP4F11
DBN1
DBNL
DCX
DDX19B
DNPH1
DOK2
DPP3
DPYSL3
ECI1
EEF1D
EIF3G
EIF4B
ENO2
ENSA
EPB41L1
EVL
FAM131B
FBP1
FES
GAMT
GAPDH
GAS2L1
GFPT2
GNMT
GPA33
GPR52
GRN
H2AC20
HAAO
HLCS
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA1A
IFRD2
IL1RN
ISYNA1
IVL
KHDRBS1
KIAA1191
KRT18
LAMC3
LASP1
LDHA
LDHB
MADD
MAGEA4
MAP4
MAP4K2
MAP7
MDM2
MICA
MT1X
MVK
MVP
MYO5C
NAP1L1
NCDN
NOL3
NUDC
NUDCD2
NXNL1
PACSIN1
PACSIN2
PAGE2
PAGE5
PAK4
PALM
PCP4
PDE1B
PDLIM2
PEX5
PFKP
PGLS
PGM1
PGM2
PHYHD1
PHYKPL
PIPOX
PRMT7
PROSER2
PYM1
RBKS
RECQL4
RGS14
RHOU
RIF1
RPAP1
RPSA
RTN4
SARS1
SBDS
SERTAD1
SH3BP1
SNCG
STIP1
STUB1
SULT1B1
SULT1C2
SULT4A1
SYAP1
TAGLN
TBCD
TERF1
TMSB10
TMSB4Y
TNKS
TOMM34
TPI1
TPP1
TRIM16
TRIP10
TUBB2A
TUBB4B
TWF2
WIPI2
XAGE2
YWHAE
YWHAG
ZBED2
ZBTB49
ZFP36L1
ZNF32
ZNF790
92 interacting genes:
ACD
ACTB
ACTC1
ANXA1
ANXA7
APP
AR
ARL15
ATN1
ATXN1
BID
BPGM
BTBD2
CAMK1
CAMK2B
CAMK4
CDKN1A
CDKN2A
CEBPA
CHP1
DUX4
DYNLL1
EGFR
ERBB2
FBXO7
FKBP6
FOXP1
GADD45A
GAS7
GOT2
GRIA2
GRM1
HES1
HNF4G
HSPB2
HTT
ITGB5
KARS1
KAT5
KCNE3
LAMA4
LAMTOR5
LIG4
LINC01554
MAPK1
MTNR1A
MYOC
NFYC
NR1H4
NUFIP2
OGT
OSMR
OSTF1
PAFAH1B3
PCDHA4
PCNA
PDIA2
PGK1
PLD2
POT1
POU2F2
PPM1E
PRDX1
PRKCI
PRPF40A
PSEN1
PSMD11
PTPRF
RAB2A
RBM5
RPA2
RXFP4
S100A6
SERPINB9
SHANK3
SIAH1
SIRT1
SLC2A1
SLC2A4
SMARCA2
SMN1
SUMO4
TERF1
TINF2
TK1
TPPP
TSC2
TXNIP
USP25
WEE2-AS1
YWHAE
YWHAQ
Entrez ID
25913
2597
HPRD ID
07572
00713
Ensembl ID
ENSG00000128513
ENSG00000111640
Uniprot IDs
A8MTK3
Q5MJ33
Q9NUX5
P04406
V9HVZ4
PDB IDs
1XJV
3KJO
3KJP
5H65
5UN7
7QXB
7QXS
7S1O
7S1T
7S1U
8SH0
8SH1
8SOJ
8SOK
1U8F
1ZNQ
3GPD
4WNC
4WNI
6ADE
6IQ6
6M61
6YND
6YNE
6YNF
6YNH
8DNS
8G12
8G13
8G14
8G15
8G16
8G17
8P5F
Enriched GO Terms of Interacting Partners
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Cytoplasm
Cytosol
Extracellular Exosome
Cytoskeleton Organization
Actin Filament Organization
Cytoskeleton
Protein Binding
Cadherin Binding
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Supramolecular Fiber Organization
Cellular Response To Heat
Actin Binding
Carbohydrate Catabolic Process
Response To Heat
Pyruvate Metabolic Process
Organelle Organization
Glycolytic Process
Nucleoside Phosphate Metabolic Process
ADP Catabolic Process
Vesicle
Purine Nucleotide Metabolic Process
Identical Protein Binding
Generation Of Precursor Metabolites And Energy
Purine Ribonucleoside Diphosphate Catabolic Process
Small Molecule Metabolic Process
Ribonucleoside Diphosphate Catabolic Process
ADP Metabolic Process
Response To Temperature Stimulus
Nucleoside Diphosphate Catabolic Process
Purine Nucleotide Catabolic Process
Ficolin-1-rich Granule Lumen
Glucose Metabolic Process
Microtubule Cytoskeleton Organization
Nucleoside Phosphate Catabolic Process
Actin Filament-based Process
Actin Cytoskeleton Organization
Monocarboxylic Acid Metabolic Process
Nucleotide Metabolic Process
Negative Regulation Of Cellular Component Organization
Cytoskeletal Protein Binding
Protein Sequestering Activity
Focal Adhesion
Catabolic Process
Monosaccharide Metabolic Process
Actin Monomer Binding
Cellular Response To Raffinose
Nucleotide Catabolic Process
Organic Acid Metabolic Process
Developmental Process
Cellular Developmental Process
Nucleus
Cell Differentiation
Regulation Of Programmed Cell Death
Regulation Of Phosphorus Metabolic Process
Shelterin Complex
Regulation Of Cellular Component Organization
Negative Regulation Of Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of DNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Signal Transduction
Regulation Of Apoptotic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Identical Protein Binding
Nuclear Telomere Cap Complex
Protein-containing Complex
Regulation Of Cellular Localization
Cellular Response To Stress
Regulation Of Cellular Response To Stress
Regulation Of Multicellular Organismal Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Protein Localization
Regulation Of DNA Metabolic Process
Telomeric DNA Binding
Telomere Capping
Regulation Of Phosphorylation
Nucleoplasm
Regulation Of Developmental Process
Negative Regulation Of DNA Biosynthetic Process
DNA Biosynthetic Process
Telomere Assembly
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Cell Cycle
Regulation Of Chromosome Organization
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Phosphate Metabolic Process
Regulation Of Cell Population Proliferation
Negative Regulation Of Biosynthetic Process
Cytosol
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Signaling
Positive Regulation Of Chromosome Organization
Positive Regulation Of Multicellular Organismal Process
Regulation Of Cell Development
Positive Regulation Of Cellular Component Organization
System Development
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Tagcloud (Intersection)
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