POT1 and ARID3B

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		POT1	ARID3B
Gene Name		protection of telomeres 1	AT rich interactive domain 3B (BRIGHT-like)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Telomerase Inhibitor Activity DEAD/H-box RNA Helicase Binding Single-stranded Telomeric DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding
	Biological Process	Telomere Maintenance Telomere Maintenance Via Telomerase Telomere Capping Telomere Formation Via Telomerase Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase DNA Duplex Unwinding Positive Regulation Of Helicase Activity Positive Regulation Of Telomerase Activity Negative Regulation Of Telomerase Activity Positive Regulation Of DNA Strand Elongation	Transcription, DNA-templated Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS			Diastolic blood pressure ( 19430483)
Protein-Protein Interactions		166 interactors: ACD ACOT7 ACTB ACTN4 ACY1 AFAP1L2 AHCY AHNAK AIPL1 ALDH1A1 ALDH3A1 AMPD2 ANKMY2 ANXA2 ANXA4 APPL2 ARHGDIA ARID3B ARRB1 BAG3 BCAS2 BIN2 C15orf57 C2orf74 CALD1 CAMK1D CCDC9 CCM2 CFL1 CFL2 CKB CLIC3 CNST CORO1A COX6A2 CPNE3 CPPED1 CRK CRYGS CSNK2B CYP4F11 DBN1 DBNL DCX DDX19B DNPH1 DOK2 DPP3 DPYSL3 ECI1 EEF1D EIF3G EIF4B ENO2 ENSA EPB41L1 EVL FAM131B FBP1 FES GAMT GAPDH GAS2L1 GFPT2 GNMT GPA33 GPR52 GRN HAAO HLCS HMOX1 HNMT HOXA3 HSP90AB1 HSPA1A IFRD2 IL1RN ISYNA1 IVL KHDRBS1 KIAA1191 KRT18 LAMC3 LASP1 LDHA LDHB MADD MAGEA4 MAP4 MAP4K2 MAP7 MDM2 MICA MT1X MVK MVP MYO5C NAP1L1 NCDN NOL3 NUDC NUDCD2 NXNL1 PACSIN1 PACSIN2 PAGE2 PAGE5 PAK4 PALM PCP4 PDE1B PDLIM2 PEX5 PFKP PGLS PGM1 PGM2 PHYHD1 PHYKPL PIPOX PRMT7 PROSER2 RBKS RECQL4 RGS14 RIF1 RPAP1 RPSA RTN4 SARS SBDS SERTAD1 SH3BP1 SNCG STIP1 STUB1 SULT1B1 SULT1C2 SULT4A1 SYAP1 TAGLN TBCD TERF1 TERF2 TINF2 TMSB10 TMSB4Y TNKS TOMM34 TPI1 TPP1 TRIM16 TRIP10 TUBB2A TUBB4B TWF2 WIBG WIPI2 XAGE2 YWHAE YWHAG ZBED2 ZBTB49 ZFP36L1 ZNF32 ZNF790	5 interactors: APP IRF9 POT1 RB1 TINF2
Entrez ID		25913	10620
HPRD ID		07572	09806
Ensembl ID		ENSG00000128513	ENSG00000179361
Uniprot IDs		A8MTK3 Q5MJ33 Q9NUX5	Q8IVW6
PDB IDs		1XJV 3KJO 3KJP
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromosome, Telomeric Region Regulation Of Telomere Maintenance Regulation Of Cellular Component Organization Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Negative Regulation Of Telomere Maintenance Small Molecule Metabolic Process Cellular Component Assembly Regulation Of Organelle Organization Negative Regulation Of Telomere Maintenance Via Telomerase Cytoskeleton Organization Organic Acid Metabolic Process Response To Stimulus Catabolic Process Regulation Of Binding Cellular Process Carboxylic Acid Metabolic Process Cofactor Metabolic Process Protein Localization To Chromosome Cellular Response To Stimulus Actin Filament Organization Protection From Non-homologous End Joining At Telomere Response To Abiotic Stimulus Carbohydrate Catabolic Process Carbohydrate Biosynthetic Process Protein Localization Telomere Assembly Telomere Capping Positive Regulation Of Organelle Organization Nervous System Development Cellular Protein Localization Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Telomere Maintenance Cellular Metabolic Process Pyruvate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Cytoskeleton Organization Negative Regulation Of DNA Replication Response To External Stimulus Actin Cytoskeleton Organization Glycolytic Process Cellular Localization Regulation Of Protein Metabolic Process Gluconeogenesis Sequestering Of Actin Monomers Regulation Of Neuron Projection Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Developmental Process	Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Protein Localization To Chromosome Neuron Maturation Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Positive Regulation Of Organelle Organization Positive Regulation Of Mitotic Cell Cycle Phase Transition Homeostatic Process Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Neuron Death Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of DNA Replication Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Catalytic Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Cell Maturation Regulation Of Protein ADP-ribosylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Synaptic Growth At Neuromuscular Junction Sister Chromatid Biorientation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Collateral Sprouting In Absence Of Injury Regulation Of Centromere Complex Assembly Telomere Formation Via Telomerase Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Nitrogen Compound Metabolic Process Chromosome Organization Maintenance Of Mitotic Sister Chromatid Cohesion
Tagcloud ?		0mug celltiter chemosensitivity ddp downregulate fluorescein formerly gastroesophageal gc iodide isothiocyanate junction n87 nci oncological oxa oxaliplatin performing pip platinum propodium ptop telomere telomeric tint1 tpp1 trastuzumab trf2 trf2ip	125b acvr1b acvr2a bak1 bcl2l2 bear bim bmpr1b cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Difference) ?		0mug celltiter chemosensitivity ddp downregulate fluorescein formerly gastroesophageal gc iodide isothiocyanate junction n87 nci oncological oxa oxaliplatin performing pip platinum propodium ptop telomere telomeric tint1 tpp1 trastuzumab trf2 trf2ip	125b acvr1b acvr2a bak1 bcl2l2 bear bim bmpr1b cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r jph2 men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a
Tagcloud (Intersection) ?