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POT1 and PRMT7
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
POT1
PRMT7
Gene Name
protection of telomeres 1
protein arginine methyltransferase 7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Cytoplasm
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Plasma Membrane
Molecular Function
Protein Binding
Telomerase Inhibitor Activity
DEAD/H-box RNA Helicase Binding
Single-stranded Telomeric DNA Binding
Histone-arginine N-methyltransferase Activity
S-adenosylmethionine-dependent Methyltransferase Activity
[myelin Basic Protein]-arginine N-methyltransferase Activity
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Protein-arginine Omega-N Symmetric Methyltransferase Activity
Histone Binding
Ribonucleoprotein Complex Binding
Histone Methyltransferase Activity (H4-R3 Specific)
Biological Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Telomere Capping
Telomere Formation Via Telomerase
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
DNA Duplex Unwinding
Positive Regulation Of Helicase Activity
Positive Regulation Of Telomerase Activity
Negative Regulation Of Telomerase Activity
Positive Regulation Of DNA Strand Elongation
Spliceosomal SnRNP Assembly
Chromatin Organization
Regulation Of Gene Expression By Genetic Imprinting
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Histone Methylation
Peptidyl-arginine Methylation
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Cell Differentiation
Histone Arginine Methylation
DNA Methylation Involved In Gamete Generation
Regulation Of Protein Binding
Histone H4-R3 Methylation
Pathways
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Chromatin modifying enzymes
Chromatin organization
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Magnesium levels (
20700443
)
Protein-Protein Interactions
166 interactors:
ACD
ACOT7
ACTB
ACTN4
ACY1
AFAP1L2
AHCY
AHNAK
AIPL1
ALDH1A1
ALDH3A1
AMPD2
ANKMY2
ANXA2
ANXA4
APPL2
ARHGDIA
ARID3B
ARRB1
BAG3
BCAS2
BIN2
C15orf57
C2orf74
CALD1
CAMK1D
CCDC9
CCM2
CFL1
CFL2
CKB
CLIC3
CNST
CORO1A
COX6A2
CPNE3
CPPED1
CRK
CRYGS
CSNK2B
CYP4F11
DBN1
DBNL
DCX
DDX19B
DNPH1
DOK2
DPP3
DPYSL3
ECI1
EEF1D
EIF3G
EIF4B
ENO2
ENSA
EPB41L1
EVL
FAM131B
FBP1
FES
GAMT
GAPDH
GAS2L1
GFPT2
GNMT
GPA33
GPR52
GRN
HAAO
HLCS
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA1A
IFRD2
IL1RN
ISYNA1
IVL
KHDRBS1
KIAA1191
KRT18
LAMC3
LASP1
LDHA
LDHB
MADD
MAGEA4
MAP4
MAP4K2
MAP7
MDM2
MICA
MT1X
MVK
MVP
MYO5C
NAP1L1
NCDN
NOL3
NUDC
NUDCD2
NXNL1
PACSIN1
PACSIN2
PAGE2
PAGE5
PAK4
PALM
PCP4
PDE1B
PDLIM2
PEX5
PFKP
PGLS
PGM1
PGM2
PHYHD1
PHYKPL
PIPOX
PRMT7
PROSER2
RBKS
RECQL4
RGS14
RIF1
RPAP1
RPSA
RTN4
SARS
SBDS
SERTAD1
SH3BP1
SNCG
STIP1
STUB1
SULT1B1
SULT1C2
SULT4A1
SYAP1
TAGLN
TBCD
TERF1
TERF2
TINF2
TMSB10
TMSB4Y
TNKS
TOMM34
TPI1
TPP1
TRIM16
TRIP10
TUBB2A
TUBB4B
TWF2
WIBG
WIPI2
XAGE2
YWHAE
YWHAG
ZBED2
ZBTB49
ZFP36L1
ZNF32
ZNF790
10 interactors:
CTCFL
DIO3
H3F3C
HIST1H3A
HIST1H4A
HIST2H2AC
MNDA
POT1
SNRPB
ZBTB24
Entrez ID
25913
54496
HPRD ID
07572
15174
Ensembl ID
ENSG00000128513
ENSG00000132600
Uniprot IDs
A8MTK3
Q5MJ33
Q9NUX5
Q9NVM4
PDB IDs
1XJV
3KJO
3KJP
Enriched GO Terms of Interacting Partners
?
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance
Regulation Of Cellular Component Organization
Regulation Of Telomere Maintenance Via Telomerase
Organelle Organization
Negative Regulation Of Telomere Maintenance
Small Molecule Metabolic Process
Cellular Component Assembly
Regulation Of Organelle Organization
Negative Regulation Of Telomere Maintenance Via Telomerase
Cytoskeleton Organization
Organic Acid Metabolic Process
Response To Stimulus
Catabolic Process
Regulation Of Binding
Cellular Process
Carboxylic Acid Metabolic Process
Cofactor Metabolic Process
Protein Localization To Chromosome
Cellular Response To Stimulus
Actin Filament Organization
Protection From Non-homologous End Joining At Telomere
Response To Abiotic Stimulus
Carbohydrate Catabolic Process
Carbohydrate Biosynthetic Process
Protein Localization
Telomere Assembly
Telomere Capping
Positive Regulation Of Organelle Organization
Nervous System Development
Cellular Protein Localization
Response To Stress
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Telomere Maintenance
Cellular Metabolic Process
Pyruvate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Regulation Of Cytoskeleton Organization
Negative Regulation Of DNA Replication
Response To External Stimulus
Actin Cytoskeleton Organization
Glycolytic Process
Cellular Localization
Regulation Of Protein Metabolic Process
Gluconeogenesis
Sequestering Of Actin Monomers
Regulation Of Neuron Projection Development
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Developmental Process
DNA Methylation
DNA Modification
DNA Replication-dependent Nucleosome Assembly
DNA Methylation On Cytosine
Chromatin Silencing At RDNA
Regulation Of Gene Expression, Epigenetic
Cellular Aromatic Compound Metabolic Process
Chromatin Silencing
Cellular Nitrogen Compound Metabolic Process
DNA Conformation Change
Nitrogen Compound Metabolic Process
Telomere Maintenance
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of DNA Strand Elongation
Chromosome Organization
Methylation
DNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Silencing
Thyroid Hormone Catabolic Process
Heterocycle Metabolic Process
Nucleosome Assembly
Gene Expression
Telomere Formation Via Telomerase
Histone H4-K20 Demethylation
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Cellular Macromolecular Complex Assembly
Negative Regulation Of Megakaryocyte Differentiation
Protein-DNA Complex Assembly
Positive Regulation Of Helicase Activity
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
DNA Packaging
Chromatin Organization
Positive Regulation Of Telomerase Activity
Telomere Assembly
Positive Regulation Of Telomere Maintenance Via Telomerase
Hormone Catabolic Process
Regulation Of Chromosome Organization
Positive Regulation Of Growth
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Cellular Component Assembly
Regulation Of Telomerase Activity
Tagcloud
?
0mug
celltiter
chemosensitivity
ddp
downregulate
fluorescein
formerly
gastroesophageal
gc
iodide
isothiocyanate
junction
n87
nci
oncological
oxa
oxaliplatin
performing
pip
platinum
propodium
ptop
telomere
telomeric
tint1
tpp1
trastuzumab
trf2
trf2ip
Tagcloud (Difference)
?
0mug
celltiter
chemosensitivity
ddp
downregulate
fluorescein
formerly
gastroesophageal
gc
iodide
isothiocyanate
junction
n87
nci
oncological
oxa
oxaliplatin
performing
pip
platinum
propodium
ptop
telomere
telomeric
tint1
tpp1
trastuzumab
trf2
trf2ip
Tagcloud (Intersection)
?