GAPDH and RBM5

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GAPDH	RBM5
Gene Name		glyceraldehyde-3-phosphate dehydrogenase	RNA binding motif protein 5
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding	Nucleotide Binding DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma	Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing Apoptotic Process Negative Regulation Of Cell Proliferation RNA Splicing Gene Expression Positive Regulation Of Apoptotic Process
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ	9 interactors: BCL2L1 GAPDH ILF3 LIG4 LRIF1 LSM8 WBP11 WDR77 ZDHHC17
Entrez ID		2597	10181
HPRD ID		00713	06052
Ensembl ID		ENSG00000111640	ENSG00000003756
Uniprot IDs		P04406	P52756
PDB IDs		1U8F 1ZNQ 2FEH 3GPD	2LK0 2LK1 2LKZ
Enriched GO Terms of Interacting Partners?		Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition	Neuron Apoptotic Process Neuron Death Response To Gamma Radiation RNA Splicing RNA Metabolic Process DNA Ligation Involved In DNA Recombination Peptidyl-cysteine S-trans-nitrosylation Apoptotic Process In Bone Marrow Negative Regulation Of Translation MRNA Processing MRNA Metabolic Process RNA Processing Response To Ionizing Radiation Suppression By Virus Of Host Apoptotic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Peptidyl-cysteine S-nitrosylation Negative Regulation Of Neuron Apoptotic Process Lagging Strand Elongation Pro-B Cell Differentiation Nucleobase-containing Compound Metabolic Process Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Negative Regulation Of Neuron Death Establishment Of Integrated Proviral Latency Positive Regulation Of Cell Proliferation Heterocycle Metabolic Process Negative Regulation Of Execution Phase Of Apoptosis Cellular Aromatic Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Neuron Apoptotic Process Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Response To Virus Cellular Nitrogen Compound Metabolic Process Regulation Of Translation Lymphoid Progenitor Cell Differentiation Apoptotic Process Gene Expression Cellular Response To Virus Regulation Of Neuron Death Modulation By Virus Of Host Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Programmed Cell Death Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane DNA Ligation Negative Regulation Of Anoikis Cell Death
Tagcloud ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	accompanied active apoptotic apparently bax caspase cord demonstrating employed establish expressions immunofluorescent labeling localization location modulating motif nervous neuronal pc12 probe promotes regulating sci spinal suppressor traumatic trigger unregulated
Tagcloud (Difference) ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	accompanied active apoptotic apparently bax caspase cord demonstrating employed establish expressions immunofluorescent labeling localization location modulating motif nervous neuronal pc12 probe promotes regulating sci spinal suppressor traumatic trigger unregulated
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