GAPDH and PDIA2

Number of citations of the paper that reports this interaction (PMID 11488911)
0

Data Source:
HPRD (in vitro)

		GAPDH	PDIA2
Gene Name		glyceraldehyde-3-phosphate dehydrogenase	protein disulfide isomerase family A, member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding	Protein Disulfide Isomerase Activity Steroid Binding Protein Binding Peptidyl-proline 4-dioxygenase Activity
	Biological Process	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma	Protein Folding Protein Retention In ER Lumen Peptidyl-proline Hydroxylation Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ	7 interactors: CALR COL2A1 CUL3 GAPDH P4HTM PPARG SST
Entrez ID		2597	64714
HPRD ID		00713	07617
Ensembl ID		ENSG00000111640	ENSG00000185615
Uniprot IDs		P04406	Q13087
PDB IDs		1U8F 1ZNQ 2FEH 3GPD
Enriched GO Terms of Interacting Partners?		Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition	Cellular Response To Lithium Ion Response To Lithium Ion Cellular Response To Organic Substance Positive Regulation Of Phagocytosis Apoptotic Process Programmed Cell Death Cell Death Death Negative Regulation Of Signal Transduction Regulation Of Phagocytosis Negative Regulation Of Signaling Response To Organic Substance Response To Steroid Hormone Negative Regulation Of Translation Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Peptide Antigen Assembly With MHC Class I Protein Complex Negative Regulation Of Pancreatic Stellate Cell Proliferation Peptidyl-cysteine S-trans-nitrosylation Response To Diuretic Protein Stabilization Response To Drug Heart Development Positive Regulation Of Endocytosis Regulation Of Cell Proliferation Regulation Of DNA Replication Cellular Response To Metal Ion Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E Hormone-mediated Signaling Pathway Regulation Of Protein Stability Cellular Response To Inorganic Substance Cell Cycle Arrest Trophectodermal Cellular Morphogenesis Sequestering Of Calcium Ion Regulation Of Endocytosis Negative Regulation Of Cellular Protein Metabolic Process Response To Temperature Stimulus Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Peptidyl-cysteine S-nitrosylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Response To Lipid Cardiovascular System Development Response To Estrogen Response To Organic Cyclic Compound Negative Regulation Of Protein Metabolic Process Negative Regulation Of Receptor Biosynthetic Process Peroxisome Proliferator Activated Receptor Signaling Pathway
Tagcloud ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	calnexin calreticulin catalysed desirable disulphide erdj5 erp44 erp57 erp72 grp78 immunocytochemical immunogens immunolocalization infective isomerase orthologues pdia10 pdia19 pdia3 pdia4 pdis spiralis thioredoxin tmx1 tmx2 tmx3 trichinella trimerization
Tagcloud (Difference) ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	calnexin calreticulin catalysed desirable disulphide erdj5 erp44 erp57 erp72 grp78 immunocytochemical immunogens immunolocalization infective isomerase orthologues pdia10 pdia19 pdia3 pdia4 pdis spiralis thioredoxin tmx1 tmx2 tmx3 trichinella trimerization
Tagcloud (Intersection) ?