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POT1 and MAP4
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
POT1
MAP4
Description
protection of telomeres 1
microtubule associated protein 4
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Shelterin Complex
Cytoplasm
Microtubule Organizing Center
Cytosol
Cytoskeleton
Microtubule
Microtubule Associated Complex
Plasma Membrane
Cilium
Axoneme
Microtubule Cytoskeleton
Axon
Ciliary Basal Body
Neuron Projection
Mitotic Spindle
Molecular Function
DNA Binding
Protein Binding
Telomerase Inhibitor Activity
DEAD/H-box RNA Helicase Binding
Telomeric DNA Binding
Single-stranded Telomeric DNA Binding
Telomeric D-loop Binding
Telomeric G-quadruplex DNA Binding
G-rich Strand Telomeric DNA Binding
8-hydroxy-2'-deoxyguanosine DNA Binding
G-rich Single-stranded DNA Binding
RNA Binding
Structural Molecule Activity
Protein Binding
Microtubule Binding
Tubulin Binding
Microtubule Stabilizing Activity
Biological Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of DNA Strand Elongation
Telomeric D-loop Disassembly
Establishment Of Protein Localization To Telomere
Positive Regulation Of Telomeric D-loop Disassembly
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Microtubule Cytoskeleton Organization
Mitotic Spindle Organization
Neuron Projection Development
Microtubule Polymerization
Microtubule Sliding
Establishment Of Spindle Orientation
Cell Division
Cilium Disassembly
Negative Regulation Of Non-motile Cilium Assembly
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Paclitaxel
Docetaxel
Artenimol
Diseases
GWAS
Chronic lymphocytic leukemia (
24292274
28165464
)
Cutaneous malignant melanoma (
26237428
)
Leukocyte telomere length (
31171785
32109421
)
Refractive error (
32231278
)
Response to selective serotonin reuptake inhibitors and depression (
27622933
)
Telomere length (
33941849
)
Blood pressure (
21909110
)
Body mass index and systole blood pressure (pairwise) (
33619380
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Diastolic blood pressure (
27618452
27841878
28739976
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Liver enzyme levels (alkaline phosphatase) (
33972514
)
Mean arterial pressure (
27618448
)
Medication use (calcium channel blockers) (
31015401
)
Pulse pressure (
27841878
)
Systolic blood pressure (
27618452
27841878
28739976
30578418
)
Interacting Genes
166 interacting genes:
ACD
ACOT7
ACTB
ACTN4
ACY1
AFAP1L2
AHCY
AHNAK
AIPL1
ALDH1A1
ALDH3A1
AMPD2
ANKMY2
ANXA2
ANXA4
APPL2
ARHGDIA
ARID3B
ARRB1
BAG3
BCAS2
BIN2
C2orf74
CALD1
CAMK1D
CCDC32
CCDC9
CCM2
CFL1
CFL2
CKB
CLIC3
CNST
CORO1A
COX6A2
CPNE3
CPPED1
CRK
CRYGS
CSNK2B
CYP4F11
DBN1
DBNL
DCX
DDX19B
DNPH1
DOK2
DPP3
DPYSL3
ECI1
EEF1D
EIF3G
EIF4B
ENO2
ENSA
EPB41L1
EVL
FAM131B
FBP1
FES
GAMT
GAPDH
GAS2L1
GFPT2
GNMT
GPA33
GPR52
GRN
H2AC20
HAAO
HLCS
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA1A
IFRD2
IL1RN
ISYNA1
IVL
KHDRBS1
KIAA1191
KRT18
LAMC3
LASP1
LDHA
LDHB
MADD
MAGEA4
MAP4
MAP4K2
MAP7
MDM2
MICA
MT1X
MVK
MVP
MYO5C
NAP1L1
NCDN
NOL3
NUDC
NUDCD2
NXNL1
PACSIN1
PACSIN2
PAGE2
PAGE5
PAK4
PALM
PCP4
PDE1B
PDLIM2
PEX5
PFKP
PGLS
PGM1
PGM2
PHYHD1
PHYKPL
PIPOX
PRMT7
PROSER2
PYM1
RBKS
RECQL4
RGS14
RHOU
RIF1
RPAP1
RPSA
RTN4
SARS1
SBDS
SERTAD1
SH3BP1
SNCG
STIP1
STUB1
SULT1B1
SULT1C2
SULT4A1
SYAP1
TAGLN
TBCD
TERF1
TMSB10
TMSB4Y
TNKS
TOMM34
TPI1
TPP1
TRIM16
TRIP10
TUBB2A
TUBB4B
TWF2
WIPI2
XAGE2
YWHAE
YWHAG
ZBED2
ZBTB49
ZFP36L1
ZNF32
ZNF790
26 interacting genes:
CCNB1
CDC42
CDK1
CEBPA
CLASP1
ENO2
ERBIN
GSK3B
IL7R
LDLR
MARK1
MARK4
NEIL3
NOP58
NR1I3
POT1
RNF10
RXRB
RXRG
SNTA1
SRPK2
STRBP
SUMO2
TERF1
TUBB
UBC
Entrez ID
25913
4134
HPRD ID
07572
01141
Ensembl ID
ENSG00000128513
ENSG00000047849
Uniprot IDs
A8MTK3
Q5MJ33
Q9NUX5
A0A804HKE7
E7EVA0
P27816
PDB IDs
1XJV
3KJO
3KJP
5H65
5UN7
7QXB
7QXS
7S1O
7S1T
7S1U
8SH0
8SH1
8SOJ
8SOK
Enriched GO Terms of Interacting Partners
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Cytoplasm
Cytosol
Extracellular Exosome
Cytoskeleton Organization
Actin Filament Organization
Cytoskeleton
Protein Binding
Cadherin Binding
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Supramolecular Fiber Organization
Cellular Response To Heat
Actin Binding
Carbohydrate Catabolic Process
Response To Heat
Pyruvate Metabolic Process
Organelle Organization
Glycolytic Process
Nucleoside Phosphate Metabolic Process
ADP Catabolic Process
Vesicle
Purine Nucleotide Metabolic Process
Identical Protein Binding
Generation Of Precursor Metabolites And Energy
Purine Ribonucleoside Diphosphate Catabolic Process
Small Molecule Metabolic Process
Ribonucleoside Diphosphate Catabolic Process
ADP Metabolic Process
Response To Temperature Stimulus
Nucleoside Diphosphate Catabolic Process
Purine Nucleotide Catabolic Process
Ficolin-1-rich Granule Lumen
Glucose Metabolic Process
Microtubule Cytoskeleton Organization
Nucleoside Phosphate Catabolic Process
Actin Filament-based Process
Actin Cytoskeleton Organization
Monocarboxylic Acid Metabolic Process
Nucleotide Metabolic Process
Negative Regulation Of Cellular Component Organization
Cytoskeletal Protein Binding
Protein Sequestering Activity
Focal Adhesion
Catabolic Process
Monosaccharide Metabolic Process
Actin Monomer Binding
Cellular Response To Raffinose
Nucleotide Catabolic Process
Organic Acid Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Cyclin B1-CDK1 Complex
Positive Regulation Of Organelle Organization
Tau-protein Kinase Activity
Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
Organelle Organization
Positive Regulation Of Metabolic Process
Cytoskeleton
Intracellular Signal Transduction
Positive Regulation Of Macromolecule Biosynthetic Process
Postsynapse
Shelterin Complex
Microtubule Cytoskeleton Organization
Cell Division
Positive Regulation Of Biosynthetic Process
Tau Protein Binding
Positive Regulation Of Protein Localization To Centrosome
Retinoic Acid-responsive Element Binding
Mitotic Spindle
Mitotic Cell Cycle Phase Transition
Cytoskeleton Organization
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Receptor Activity
Nuclear Telomere Cap Complex
Telomeric D-loop Disassembly
Ventricular Cardiac Muscle Cell Development
Cell Cycle Phase Transition
Establishment Or Maintenance Of Cell Polarity
G-rich Strand Telomeric DNA Binding
Regulation Of Cell Cycle
Positive Regulation Of Cell Cycle
Cilium Disassembly
Telomeric Loop Disassembly
Nucleoplasm
Response To Lipid
Microtubule-based Process
Regulation Of Protein Localization To Centrosome
Telomere Capping
Protein Phosphorylation
Glutamatergic Synapse
Protein Serine Kinase Activity
Positive Regulation Of Protein-containing Complex Assembly
Protein Tag Activity
Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Organelle Organization
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Cell Cycle G1/S Phase Transition
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Tagcloud (Difference)
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Tagcloud (Intersection)
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