GAPDH and OSMR

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GAPDH	OSMR
Gene Name		glyceraldehyde-3-phosphate dehydrogenase	oncostatin M receptor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex	Oncostatin-M Receptor Complex
	Molecular Function	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding	Oncostatin-M Receptor Activity Growth Factor Binding
	Biological Process	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma	Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Cell Proliferation Response To Cytokine Oncostatin-M-mediated Signaling Pathway
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ	5 interactors: GAPDH IL6ST JAK1 JAK2 OSM
Entrez ID		2597	9180
HPRD ID		00713	03446
Ensembl ID		ENSG00000111640	ENSG00000145623
Uniprot IDs		P04406	Q99650
PDB IDs		1U8F 1ZNQ 2FEH 3GPD
Enriched GO Terms of Interacting Partners?		Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition	Cellular Response To Cytokine Stimulus Response To Cytokine Tyrosine Phosphorylation Of Stat1 Protein Tyrosine Phosphorylation Of Stat5 Protein Oncostatin-M-mediated Signaling Pathway Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Inflammatory Response Cytokine-mediated Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Tyrosine Phosphorylation Of STAT Protein Cellular Response To Interferon-gamma Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Response To Organic Substance Response To Interferon-gamma Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Acute Inflammatory Response Peptidyl-amino Acid Modification Response To Organic Substance Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Inflammatory Response Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Immune Response Regulation Of Cellular Amino Acid Metabolic Process JAK-STAT Cascade Response To Antibiotic Positive Regulation Of JAK-STAT Cascade Regulation Of Cell Proliferation Regulation Of Cellular Ketone Metabolic Process Regulation Of Acute Inflammatory Response Regulation Of JAK-STAT Cascade Host Programmed Cell Death Induced By Symbiont Interleukin-11-mediated Signaling Pathway Peptidyl-cysteine S-trans-nitrosylation Histone H3-Y41 Phosphorylation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Interferon-gamma-mediated Signaling Pathway Immune System Process Regulation Of Protein Metabolic Process Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Proliferation Interleukin-27-mediated Signaling Pathway Mineralocorticoid Receptor Signaling Pathway Positive Regulation Of Phosphorylation
Tagcloud ?		apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	apart auuua closed dependently dispensable ehlting erk1 fr180204 hepatocytes integrates intercellular involves knock mek1 mk2 osmrbeta p38mapk pentameric proximity sb203580 sensing socs socs3 stabilization transcript u0126 unexpectedly utr
Tagcloud (Difference) ?		caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced	auuua closed dependently dispensable ehlting erk1 fr180204 hepatocytes integrates intercellular involves knock mek1 mk2 osmrbeta p38mapk pentameric proximity sb203580 sensing socs socs3 stabilization transcript u0126 unexpectedly utr
Tagcloud (Intersection) ?		apart