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DCX and FBXO25
Number of citations of the paper that reports this interaction (PMID
23940030
)
0
Data Source:
BioGRID
(enzymatic study)
DCX
FBXO25
Gene Name
doublecortin
F-box protein 25
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Cytoskeleton
Microtubule
Microtubule Associated Complex
Neuron Projection
Ubiquitin Ligase Complex
Nucleus
Nucleolus
SCF Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Microtubule Binding
Protein Kinase Binding
Actin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Biological Process
Neuron Migration
Nervous System Development
Axon Guidance
Central Nervous System Development
Brain Development
Central Nervous System Projection Neuron Axonogenesis
Intracellular Signal Transduction
Axon Extension
Dendrite Morphogenesis
Protein Ubiquitination
Pathways
Axon guidance
Neurofascin interactions
L1CAM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions
29 interactors:
ACD
AP1M1
AP2M1
APP
CALCOCO2
CDK5
FBXO25
GOLGA2
IKZF1
KIFC3
KRT40
KRTAP10-8
MEOX1
MID2
NFASC
PAFAH1B1
POT1
PPP1CA
PPP1R9B
RINT1
SPAG5
SPP1
TERF1
TINF2
TRIM23
TRIM27
TRIM39
USP9X
ZBTB5
80 interactors:
ADRBK1
ANKRD13A
APLF
AXL
BMX
C11orf63
C19orf57
C6orf106
C7orf50
CDK5RAP2
CDK9
CENPB
CUL1
CXXC4
DCX
DDX42
DEPTOR
DNAJB2
DNAJC8
DYRK3
DYRK4
EGFR
EID3
EIF4E2
ELK1
EPN1
FKBP3
G3BP1
GTF2B
GTF2IRD2
HIP1
HMCES
HP1BP3
IL21
ING3
IRS1
KDR
KRT8
LMCD1
LUC7L
MAT2B
NSRP1
NUAK1
ODF2
ORC4
PADI4
PAK4
PCK1
PDGFRA
PIP4K2C
PPID
PPP1R8
PRKCA
PRKG2
PRR15
PRRG1
PSMD4
RABEP2
RBM8A
RHBDD1
RIOK3
RPAP3
RPS10
RPS6KB2
SAMHD1
SERBP1
SKP1
STAC
SYTL2
TCEAL2
TCEANC
TCP10L
TMA7
TNIP2
TRUB1
TWF1
UBE2D3
UBQLN1
UBQLN2
WDSUB1
Entrez ID
1641
26260
HPRD ID
02127
16439
Ensembl ID
ENSG00000077279
ENSG00000147364
Uniprot IDs
A8K340
B4DM53
O43602
Q8TCJ0
PDB IDs
1MJD
2BQQ
2XRP
4ATU
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Telomere Assembly
Negative Regulation Of DNA Replication
Regulation Of Telomerase Activity
Negative Regulation Of Cellular Metabolic Process
Telomere Maintenance
Cell Cycle
Negative Regulation Of Chromosome Organization
Regulation Of Cellular Component Organization
Negative Regulation Of DNA Metabolic Process
Regulation Of Organelle Organization
Cell Division
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Biosynthetic Process
Organelle Organization
Regulation Of DNA Replication
Regulation Of Developmental Growth
Protein Localization To Chromosome, Telomeric Region
Telomere Capping
Regulation Of DNA Biosynthetic Process
Movement Of Cell Or Subcellular Component
Axonogenesis
Cellular Component Assembly
Protein Localization
Positive Regulation Of Telomerase Activity
Neuron Projection Development
Cellular Localization
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Locomotion
Regulation Of Growth
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomerase Activity
Negative Regulation Of Neuron Differentiation
Neuron Projection Morphogenesis
Neuron Development
Immune System Process
Positive Regulation Of Telomere Maintenance
Hippocampus Development
Positive Regulation Of Organelle Organization
Regulation Of Chromosome Organization
Regulation Of Mitotic Cell Cycle
Cell Morphogenesis Involved In Differentiation
Forebrain Development
Developmental Cell Growth
Negative Regulation Of Viral Release From Host Cell
Neuron Differentiation
Regulation Of Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Cellular Protein Modification Process
Enzyme Linked Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Viral Process
Protein Phosphorylation
Cellular Response To Stimulus
Cellular Response To Growth Factor Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Response To Growth Factor
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Gene Expression
Peptidyl-tyrosine Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of Phospholipase C Activity
Phosphorylation
Intracellular Signal Transduction
Regulation Of Cellular Process
Rhythmic Process
Protein Autophosphorylation
Positive Regulation Of Phospholipase Activity
Response To Stimulus
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Immune Response
Proteasomal Protein Catabolic Process
G1/S Transition Of Mitotic Cell Cycle
Response To UV-A
Peptidyl-serine Autophosphorylation
Regulation Of Phospholipase Activity
Apoptotic Process
Positive Regulation Of Lipase Activity
Defense Response
Protein Metabolic Process
Regulation Of Cell Death
Immune System Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Tagcloud
?
17p13
classical
deletions
disrupt
epilepsy
frontal
gradient
lis
lis1
lissencephaly
malformation
mutations
occipital
overlapping
parietal
proline
q23
repeats
retardation
sequencing
sexes
southern
splice
sporadic
though
truncation
wd40
xlis
xq22
Tagcloud (Difference)
?
17p13
classical
deletions
disrupt
epilepsy
frontal
gradient
lis
lis1
lissencephaly
malformation
mutations
occipital
overlapping
parietal
proline
q23
repeats
retardation
sequencing
sexes
southern
splice
sporadic
though
truncation
wd40
xlis
xq22
Tagcloud (Intersection)
?