DCX and FSD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DCX	FSD2
Description		doublecortin	fibronectin type III and SPRY domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Cell Projection Neuron Projection	Nucleus Cytoplasm Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding	Protein Binding
	Biological Process	Neuron Migration Nervous System Development Central Nervous System Development Cell Differentiation Axoneme Assembly Intracellular Signal Transduction Retina Development In Camera-type Eye
Pathways		Neurofascin interactions
Drugs
Diseases		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS			HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Tourette syndrome ( 30818990)
Interacting Genes		39 interacting genes: ACD AP1M1 AP2M1 APP BICD2 CALCOCO2 CDK5 FBXO25 FSD2 GOLGA2 HOOK2 IKZF1 KIFC3 KRT40 KRTAP10-8 MAPK9 MEOX1 MEOX2 MID2 MTUS2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RBM5 RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X VPS52 ZBTB10 ZBTB5 ZRANB1	93 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26
Entrez ID		1641	123722
HPRD ID		02127	17291
Ensembl ID		ENSG00000077279	ENSG00000186628
Uniprot IDs		A0A1B0GWD1 A0A7P0T9C5 A0A804CF28 A8K340 O43602	A1L4K1 B7ZM05
PDB IDs		1MJD 2BQQ 2XRP 4ATU 5IKC 5IN7 5IO9 5IOI 5IP4 6FNZ 6REV 6RF2 6RF8 6RFD
Enriched GO Terms of Interacting Partners?		Shelterin Complex Microtubule Binding Telomeric DNA Binding Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Intracellular Protein Localization Negative Regulation Of Telomere Maintenance Via Telomerase Intracellular Transport Establishment Of Localization In Cell Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Microtubule Negative Regulation Of Telomere Maintenance Cellular Localization Protein Transport Establishment Of Protein Localization Telomere Maintenance Chromosome, Telomeric Region Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Component Organization Acetylcholine Receptor Activator Activity Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Cellular Component Organization Telomere Organization Cytoskeleton Growth Cone Organelle Organization Positive Regulation Of Organelle Organization Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance RNA-templated DNA Biosynthetic Process Negative Regulation Of Chromosome Organization Vesicle-mediated Transport Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Regulation Of Organelle Organization Somite Specification Cell Division Regulation Of Establishment Of Protein Localization To Telomere Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Binding Positive Regulation Of Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Supramolecular Fiber Organization Regulation Of Telomere Maintenance Chromosome Organization	Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Regulation Of Metabolic Process Centriole Microtubule Anchoring Microtubule Binding
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