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TRIM54 and SPG21
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
TRIM54
SPG21
Gene Name
tripartite motif containing 54
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Microtubule
Microtubule Associated Complex
Z Disc
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Molecular Function
Signal Transducer Activity
Microtubule Binding
Zinc Ion Binding
Protein Binding
CD4 Receptor Binding
Biological Process
Microtubule-based Process
Negative Regulation Of Microtubule Depolymerization
Signal Transduction
Multicellular Organismal Development
Cell Differentiation
Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
127 interactors:
ADCY4
ALS2CR11
ARFIP2
ARHGEF5
ATXN3
ATXN3L
ATXN7
BYSL
C12orf49
C1orf109
C1orf216
C1QTNF2
CALM3
CARD9
CCDC102B
CCDC146
CCDC28A
CCDC67
CCDC87
CDK18
CDKN1A
CEP57L1
CHCHD2
CKM
CRADD
CWF19L2
CYTH4
DCUN1D1
DNAL4
DTX2
EHHADH
EIF4E2
ELMO1
ENKD1
EPM2AIP1
EXOSC5
FAM110A
FAM124A
FAM124B
FAM161A
FARS2
FBF1
FLNC
GEM
GMCL1
GTF2IRD2
HAUS1
ING3
INPP5J
IQUB
JOSD1
KDM1A
KIFC3
KLHL38
KPNA2
KRT6A
KRT6B
KRT6C
LENG1
LIN37
LMO2
LNX1
LSM2
MAPK3
MBD3
MCM7
MEAF6
MFAP1
MID2
MYO5B
NGLY1
OSTF1
OTUB1
OTUB2
PIK3R3
PPP1R18
PRF1
RABGEF1
RAD23A
RBM41
RCOR3
RSRC2
SCNM1
SDCBP
SENP3
SH2D1B
SMARCE1
SNF8
SPG21
SSX2IP
STAM
STRA13
TBC1D22B
TCEA2
TCEB3
THOC1
TRIM55
TRIM63
TSHZ3
TTC23
UBE2D3
UBE2I
UBE2U
UCHL1
UCHL3
UCHL5
USHBP1
USP15
USP18
USP2
USP21
USP33
USP4
USP5
USP7
USP8
UTP14C
VPS28
WDR34
WDYHV1
YOD1
ZBTB16
ZGPAT
ZNF250
ZNF417
ZNF572
ZNF587
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
Entrez ID
57159
51324
HPRD ID
05928
10492
Ensembl ID
ENSG00000138100
ENSG00000090487
Uniprot IDs
Q9BYV2
Q9NZD8
PDB IDs
3Q1D
Enriched GO Terms of Interacting Partners
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Protein Deubiquitination
Protein Modification By Small Protein Removal
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein Catabolic Process
Cellular Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Protein K63-linked Deubiquitination
Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Cellular Protein Metabolic Process
Regulation Of Metabolic Process
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Organelle Organization
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Histone Deubiquitination
RNA Metabolic Process
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Cellular Process
Monoubiquitinated Protein Deubiquitination
Histone Modification
Gene Expression
RNA Biosynthetic Process
Chromatin Modification
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Proteolysis
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Chromatin Organization
Cellular Response To DNA Damage Stimulus
Nitrogen Compound Metabolic Process
Chromosome Organization
Cellular Response To Heat
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
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Tagcloud (Intersection)
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