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SPG21 and ARMC12
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
SPG21
ARMC12
Description
SPG21 abhydrolase domain containing, maspardin
armadillo repeat containing 12
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endosome
Golgi Apparatus
Cytosol
Endosome Membrane
Membrane
Trans-Golgi Network Transport Vesicle
Nucleus
Mitochondrion
Mitochondrial Outer Membrane
Membrane
Molecular Function
Protein Binding
CD4 Receptor Binding
Protein Binding
Biological Process
Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Locomotory Behavior
Gene Expression
Neuron Maturation
Collateral Sprouting
Antigen Receptor-mediated Signaling Pathway
Neuromuscular Process
Limb Development
Response To Epidermal Growth Factor
Spermatogenesis
Cell Differentiation
Positive Regulation Of Cell Growth
Flagellated Sperm Motility
Sperm Mitochondrial Sheath Assembly
Pathways
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
GWAS
Depression x herpes simplex 1 infection interaction (
32564518
)
Eosinophil percentage of granulocytes (
27863252
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
161 interacting genes:
-
ACOT13
AGTR1
AGTRAP
AKIRIN2
APOC1
ARL6IP1
ARMC12
ARMC7
ATP5ME
BORCS6
BSND
CCDC102B
CCDC33
CCHCR1
CD4
CDK2AP1
CDKN2B
CEP76
CEPT1
CFAP410
CIDEB
CLDN22
CMTM4
CMTM5
CMTM6
COG3
COG6
CPSF7
CRX
CRYAA
CT55
CTIF
CTPS2
CUTC
DCTPP1
DRC12
DRC4
DTX3L
EFHC2
EIF1B
EIF4H
EYA2
FAM114A1
FAM86C1P
FBXO44
FLACC1
GAD2
GEMIN2
GEMIN4
GGA2
GOLGA2
GOLT1B
GRPEL1
GSK3A
HNRNPH1
HPRT1
HSD17B13
IKZF3
INCA1
IQCB1
KCTD9
KRT13
KRT15
KRT19
KRT31
LEPROTL1
LMNA
LMO1
LNX1
LSMEM2
MAB21L3
MID2
MPC2
MTMR9
MTUS2
MYG1
MYOG
N4BP3
NAB2
NDUFAF2
NIF3L1
NME4
NQO2
NR1D1
NRDE2
NUP54
PAX6
PBX4
PCBD2
PCNA
PDE5A
PEF1
PFDN5
PLP2
PNMA5
PPM1J
PRPS1
PRTFDC1
PSMB4
PTPA
RABAC1
RAD51C
REEP6
REL
ROPN1
RPRD1B
RPS19
RTL8B
RTN4
S100B
SATB1
SCAMP1
SEPTIN5
SFT2D1
SH3GL1
SLC35E3
SORBS3
SPMIP5
SPMIP6
SPRED1
SPRED2
SRGAP2B
SSBP4
SWSAP1
SYNGR1
SYNGR3
SYP
TCF12
TCF4
TEKT4
TFG
TFIP11
TLE5
TMEM208
TMEM239
TOX2
TPD52
TRAF1
TRAF2
TRIB3
TRIM14
TRIM23
TRIM50
TRIM54
TRIM9
TSGA10IP
TSNAXIP1
TTC23L
TXN
TXNL4B
UFSP1
USHBP1
VMAC
VPS25
YPEL3
ZBTB42
ZMYND12
ZNF263
ZNF581
ZNF629
8 interacting genes:
EHHADH
FA2H
GAD2
RBBP4
SENP2
SNX1
SPG21
TTPA
Entrez ID
51324
221481
HPRD ID
10492
12901
Ensembl ID
ENSG00000090487
ENSG00000157343
Uniprot IDs
Q9NZD8
Q5T9G4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Binding
Identical Protein Binding
Motile Cilium
Structural Molecule Activity
Guanine Salvage
Purine Nucleobase Biosynthetic Process
Hypoxanthine Phosphoribosyltransferase Activity
Flagellated Sperm Motility
Sperm Motility
Cilium-dependent Cell Motility
Sperm Flagellum
Cilium Movement Involved In Cell Motility
Hypoxanthine Biosynthetic Process
Protein-containing Complex Organization
Small Molecule Biosynthetic Process
Carboxylic Acid Biosynthetic Process
Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity
Intramolecular Oxidoreductase Activity, Transposing C=C Bonds
Gamma-aminobutyrate Shunt
Glutamate Decarboxylase Activity
Negative Regulation Of Establishment Of Blood-brain Barrier
Sebaceous Gland Cell Differentiation
4-hydroxysphinganine Ceramide Fatty Acyl 2-hydroxylase Activity
Free Fatty Acid 2-hydroxylase Activity
Glucosylceramide Biosynthetic Process
Fatty Acid 2-hydroxylase Activity
Regulation Of Sebum Secreting Cell Proliferation
Regulation Of Acinar Cell Proliferation
Monocarboxylic Acid Metabolic Process
Fatty Acid Biosynthetic Process
CAF-1 Complex
Regulation Of Establishment Of Blood-brain Barrier
Vitamin E Binding
Central Nervous System Myelin Maintenance
Organic Acid Metabolic Process
Lyase Activity
Carboxylic Acid Metabolic Process
Lipid Modification
Enoyl-CoA Hydratase Activity
(3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity
Delta(3)-delta(2)-enoyl-CoA Isomerase Activity
3-hydroxyacyl-CoA Dehydratase Activity
Cytosol
Gamma-aminobutyric Acid Biosynthetic Process
L-glutamate Catabolic Process
Gamma-aminobutyric Acid Metabolic Process
Succinate Metabolic Process
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
DNA Replication-dependent Chromatin Assembly
NURF Complex
Retromer, Tubulation Complex
Lamellipodium Morphogenesis
Leptin Receptor Binding
Vitamin E Metabolic Process
Positive Regulation Of Amyloid-beta Clearance
SUMO-specific Endopeptidase Activity
DeSUMOylase Activity
Regulation Of DNA Endoreduplication
Galactosylceramide Biosynthetic Process
Galactosylceramide Metabolic Process
Glucosylceramide Metabolic Process
Peripheral Nervous System Myelin Maintenance
Carboxylic Acid Catabolic Process
Carbon-carbon Lyase Activity
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Tagcloud (Intersection)
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