SPG21 and KCTD9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPG21	KCTD9
Description		SPG21 abhydrolase domain containing, maspardin	potassium channel tetramerization domain containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Transport Vesicle
	Molecular Function	Protein Binding CD4 Receptor Binding	Protein Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Locomotory Behavior Gene Expression Neuron Maturation Collateral Sprouting Antigen Receptor-mediated Signaling Pathway Neuromuscular Process Limb Development Response To Epidermal Growth Factor	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS			Lymphocyte count ( 32888494)
Interacting Genes		161 interacting genes: - ACOT13 AGTR1 AGTRAP AKIRIN2 APOC1 ARL6IP1 ARMC12 ARMC7 ATP5ME BORCS6 BSND CCDC102B CCDC33 CCHCR1 CD4 CDK2AP1 CDKN2B CEP76 CEPT1 CFAP410 CIDEB CLDN22 CMTM4 CMTM5 CMTM6 COG3 COG6 CPSF7 CRX CRYAA CT55 CTIF CTPS2 CUTC DCTPP1 DRC12 DRC4 DTX3L EFHC2 EIF1B EIF4H EYA2 FAM114A1 FAM86C1P FBXO44 FLACC1 GAD2 GEMIN2 GEMIN4 GGA2 GOLGA2 GOLT1B GRPEL1 GSK3A HNRNPH1 HPRT1 HSD17B13 IKZF3 INCA1 IQCB1 KCTD9 KRT13 KRT15 KRT19 KRT31 LEPROTL1 LMNA LMO1 LNX1 LSMEM2 MAB21L3 MID2 MPC2 MTMR9 MTUS2 MYG1 MYOG N4BP3 NAB2 NDUFAF2 NIF3L1 NME4 NQO2 NR1D1 NRDE2 NUP54 PAX6 PBX4 PCBD2 PCNA PDE5A PEF1 PFDN5 PLP2 PNMA5 PPM1J PRPS1 PRTFDC1 PSMB4 PTPA RABAC1 RAD51C REEP6 REL ROPN1 RPRD1B RPS19 RTL8B RTN4 S100B SATB1 SCAMP1 SEPTIN5 SFT2D1 SH3GL1 SLC35E3 SORBS3 SPMIP5 SPMIP6 SPRED1 SPRED2 SRGAP2B SSBP4 SWSAP1 SYNGR1 SYNGR3 SYP TCF12 TCF4 TEKT4 TFG TFIP11 TLE5 TMEM208 TMEM239 TOX2 TPD52 TRAF1 TRAF2 TRIB3 TRIM14 TRIM23 TRIM50 TRIM54 TRIM9 TSGA10IP TSNAXIP1 TTC23L TXN TXNL4B UFSP1 USHBP1 VMAC VPS25 YPEL3 ZBTB42 ZMYND12 ZNF263 ZNF581 ZNF629	91 interacting genes: ACTMAP ADAMTSL4 ANKS1A AQP1 ARID5A BANP BLZF1 CARD9 CBX8 CCDC33 CDC37 CDPF1 CFP CRADD DDIT4L DEUP1 EHHADH EPM2AIP1 FAM124B GEM GOLGA6L9 GORASP2 GPANK1 HOXA1 HOXC8 IGFN1 IL16 INCA1 KIF9 KLHL26 KRT31 KRT34 KRT35 KRT40 KRTAP13-2 KRTAP13-3 LNX1 LONRF1 MAD2L2 MBD3L1 MEOX2 MIIP MVP NDUFAB1 NIF3L1 NTAQ1 PDZD4 PFDN5 PICK1 PLOD3 PNKD POF1B PPP1R16B PPP1R18 PRDM6 PRKAA2 PSMA1 PSMB2 RBPMS RFX6 RUSC1 SAXO4 SDCBP SKP1 SLAIN1 SMARCB1 SMUG1 SPATS1 SPG21 SPMIP4 SPMIP6 SPMIP9 STX11 SYT6 TASOR2 TEPSIN TNS2 TRIM27 TRIM32 TRIM42 TRIP6 UNKL USP21 USP54 WDR83 ZBTB25 ZBTB42 ZNF408 ZNF426 ZNF620 ZNF76
Entrez ID		51324	54793
HPRD ID		10492	13772
Ensembl ID		ENSG00000090487	ENSG00000104756
Uniprot IDs		Q9NZD8	Q7L273
PDB IDs			5BXH
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Motile Cilium Structural Molecule Activity Guanine Salvage Purine Nucleobase Biosynthetic Process Hypoxanthine Phosphoribosyltransferase Activity Flagellated Sperm Motility Sperm Motility Cilium-dependent Cell Motility Sperm Flagellum Cilium Movement Involved In Cell Motility Hypoxanthine Biosynthetic Process Protein-containing Complex Organization	Protein Binding Identical Protein Binding
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