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SPG21 and CCDC33
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPG21
CCDC33
Gene Name
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
coiled-coil domain containing 33
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Molecular Function
Protein Binding
CD4 Receptor Binding
Protein Binding
Biological Process
Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
91 interactors:
ABCF3
ABLIM3
APP
ARIH2
ARMC7
ARNT2
BCCIP
BLK
BLZF1
BYSL
CALCOCO2
CCDC102B
CCDC85B
CCNH
CDCA7L
CDKN2B
CENPP
CHCHD3
DGCR6
DIP2A
DVL2
EFEMP2
EHMT2
EMC2
EMD
FAM124A
FAM161A
FXR2
GPATCH2L
GRN
HGS
HNRNPF
HNRNPK
HOOK2
HOXA1
ING5
KANK2
KCTD19
KCTD9
KHDRBS3
KIFC3
KXD1
LDOC1
LMO2
LMO3
MAGED1
MAPK9
MDFI
MIPOL1
MOS
NAB2
NCK2
NDOR1
NECAB2
NINL
OSGIN1
PID1
PIN1
PLSCR1
PNMA1
PNMA2
POLR1C
PPP2R3C
PRKAB2
PTGER3
PTK6
RAD54B
RBMX
RHOXF2
SCNM1
SMAD3
SPAG5
SPG21
SSSCA1
STK16
STX11
TGFB1
TMCC2
TRAF2
TRIM37
TRIM42
TSC22D4
TSGA10
TTC19
TUFT1
UBQLN4
USHBP1
VPS52
ZBTB8A
ZGPAT
ZNF572
Entrez ID
51324
80125
HPRD ID
10492
09959
Ensembl ID
ENSG00000090487
ENSG00000140481
Uniprot IDs
Q9NZD8
Q8N5R6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Protein Phosphorylation
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Phosphorylation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Protein Kinase Activity
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of Transcription, DNA-templated
Regulation Of Phosphorus Metabolic Process
RNA Metabolic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Cellular Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Proliferation
Negative Regulation Of Phosphorylation
Cellular Nitrogen Compound Metabolic Process
Immune System Process
Transcription From RNA Polymerase II Promoter
Cell Cycle Process
Evasion Or Tolerance Of Host Defenses By Virus
Regulation Of Cellular Process
Regulation Of Cell Cycle
Response To Organic Substance
Organelle Organization
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Extracellular Matrix Assembly
Positive Regulation Of Metabolic Process
Negative Regulation Of Cell Proliferation
Positive Regulation Of MAP Kinase Activity
Nitrogen Compound Metabolic Process
Negative Regulation Of Protein Phosphorylation
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Tagcloud (Intersection)
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