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SPG21 and ARL6IP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPG21
ARL6IP1
Gene Name
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
ADP-ribosylation factor-like 6 interacting protein 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Sec61 Translocon Complex
Cytosol
Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
CD4 Receptor Binding
Protein Binding
Biological Process
Antigen Receptor-mediated Signaling Pathway
Cotranslational Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
40 interactors:
ACSF2
ARL4D
ARL6
C12orf10
COL4A3BP
DIABLO
FAM134C
FBXW7
FDFT1
FXR2
GAD2
GOLPH3
GORASP2
HGS
HMGCL
INPP5K
MTERF3
NAPB
NDRG4
NUDT3
PAM16
PBX3
RAB33A
RTN4
SENP2
SHMT2
SNX1
SNX10
SNX11
SNX12
SNX15
SNX3
SNX4
SPG21
SUCLA2
TFAM
TUFM
WIPI2
ZFYVE21
ZNF391
Entrez ID
51324
23204
HPRD ID
10492
09641
Ensembl ID
ENSG00000090487
ENSG00000170540
Uniprot IDs
Q9NZD8
B7Z6S5
F5GXP4
Q15041
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Protein Transport
Establishment Of Protein Localization
Protein Localization
Cellular Localization
Vesicle Organization
Establishment Of Localization In Cell
Intracellular Transport
Organelle Organization
Cellular Protein Localization
Intracellular Protein Transport
Negative Regulation Of Early Endosome To Late Endosome Transport
Mitochondrion Organization
Regulation Of DNA Endoreduplication
Succinate Metabolic Process
Regulation Of Early Endosome To Late Endosome Transport
Transport
Protein Localization To Cilium
Regulation Of Protein Catabolic Process
Membrane Invagination
Endomembrane System Organization
Negative Regulation Of Intracellular Transport
Cell Projection Assembly
Protein Localization To Organelle
Vesicle-mediated Transport
Negative Regulation Of SREBP Signaling Pathway
Succinyl-CoA Pathway
Diphosphoinositol Polyphosphate Catabolic Process
Posterior Compartment Specification
Anterior Compartment Pattern Formation
Positive Regulation Of Renal Water Transport
Diadenosine Polyphosphate Catabolic Process
Intralumenal Vesicle Formation
Membrane Organization
Localization Within Membrane
Protein Localization To Membrane
Endoplasmic Reticulum Organization
Regulation Of Vesicle-mediated Transport
Inositol Phosphate Metabolic Process
Negative Regulation Of Protein Transport
Lamellipodium Organization
Alcohol Catabolic Process
Glutamate Decarboxylation To Succinate
Negative Regulation Of Triglyceride Biosynthetic Process
ER To Golgi Ceramide Transport
Uroporphyrinogen III Biosynthetic Process
Cell Adhesion Molecule Production
Intermembrane Transport
Endosomal Transport
Protein Targeting
Biosynthetic Process
Tagcloud
?
1a
2b
3c
4c
cisternae
elaborate
elucidated
envelope
er
exogenously
harboring
homology
interconnected
localizes
organelle
potency
reticulon
reticulons
shaped
shaping
sheet
sheets
suppress
suppresses
tmem33
transmembrane
tubular
tubulation
tubules
Tagcloud (Difference)
?
1a
2b
3c
4c
cisternae
elaborate
elucidated
envelope
er
exogenously
harboring
homology
interconnected
localizes
organelle
potency
reticulon
reticulons
shaped
shaping
sheet
sheets
suppress
suppresses
tmem33
transmembrane
tubular
tubulation
tubules
Tagcloud (Intersection)
?