TRIM54 and ATXN7

Number of citations of the paper that reports this interaction (PMID 21078624)
14

Data Source:
BioGRID (two hybrid)

		TRIM54	ATXN7
Gene Name		tripartite motif containing 54	ataxin 7
Image
Gene Ontology Annotations	Cellular Component	Microtubule Microtubule Associated Complex Z Disc	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Cytoskeleton Nuclear Matrix
	Molecular Function	Signal Transducer Activity Microtubule Binding Zinc Ion Binding	Chromatin Binding Protein Binding
	Biological Process	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organismal Development Cell Differentiation	Microtubule Cytoskeleton Organization Chromatin Organization Transcription, DNA-templated Nucleus Organization Visual Perception Histone Deubiquitination Negative Regulation Of Phosphorylation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		127 interactors: ADCY4 ALS2CR11 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC67 CCDC87 CDK18 CDKN1A CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM STRA13 TBC1D22B TCEA2 TCEB3 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D3 UBE2I UBE2U UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 WDYHV1 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587	59 interactors: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN HIST1H3A JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SSFA2 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 VCP VWF
Entrez ID		57159	6314
HPRD ID		05928	06365
Ensembl ID		ENSG00000138100	ENSG00000163635
Uniprot IDs		Q9BYV2	O15265 Q9UPD8
PDB IDs		3Q1D	2KKR
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Organization Regulation Of Protein Catabolic Process Protein Metabolic Process Histone Deubiquitination RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Process Monoubiquitinated Protein Deubiquitination Histone Modification Gene Expression RNA Biosynthetic Process Chromatin Modification Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromatin Organization Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Chromosome Organization Cellular Response To Heat Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process	Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Cell-substrate Junction Assembly Cell-substrate Adhesion Platelet Degranulation Cellular Localization Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Vesicle-mediated Transport Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Cell Junction Assembly Protein Localization To Tight Junction Regulation Of Metabolic Process Histone Deubiquitination Regulation Of Cellular Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Response To Wounding Regulation Of Protein Catabolic Process Regulation Of Cell Death Protein Ubiquitination Protein Polyubiquitination Blood Coagulation Cellular Protein Modification Process Hemostasis Positive Regulation Of Proteolysis Focal Adhesion Assembly Cellular Component Assembly Protein Localization Extracellular Matrix Disassembly Platelet Activation Regulation Of Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Protein Complex Assembly Regulation Of Signaling Cellular Protein Metabolic Process Protein Localization To Cell Junction Cell Death Death Response To Stress Nervous System Development Positive Regulation Of Protein Catabolic Process Secretion By Cell Substrate Adhesion-dependent Cell Spreading Adherens Junction Assembly Protein Metabolic Process
Tagcloud ?			accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Difference) ?			accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Intersection) ?