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SPG21 and CMTM5
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPG21
CMTM5
Gene Name
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
CKLF-like MARVEL transmembrane domain containing 5
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Extracellular Space
Integral Component Of Membrane
Molecular Function
Protein Binding
CD4 Receptor Binding
Cytokine Activity
Biological Process
Antigen Receptor-mediated Signaling Pathway
Chemotaxis
Negative Regulation Of Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
46 interactors:
AACS
ACSF2
ALDH18A1
APOA1
ARMC9
C12orf10
CPLX1
CYP1A1
DDA1
FAM114A1
FARS2
GAD1
GAD2
GLTP
GOLGA2P10
GTF3C1
KIAA0368
LMO2
MCEE
MTERF3
NDRG4
PITPNC1
PLIN3
PPIF
PPP2R3C
PTPN9
RBFA
RMDN2
RNF185
RSRC2
SDCBP
SH3GLB1
SHMT2
SNX1
SPATA8
SPG21
SSX3
SUCLA2
SYNE4
TIMM44
TPD52L3
TTPA
TUBB
TUFM
VARS2
ZNF391
Entrez ID
51324
116173
HPRD ID
10492
06986
Ensembl ID
ENSG00000090487
ENSG00000166091
Uniprot IDs
Q9NZD8
C9JAI6
Q96DZ9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Carboxylic Acid Metabolic Process
Succinate Metabolic Process
Organic Acid Metabolic Process
Glutamate Decarboxylation To Succinate
Glutamate Metabolic Process
Dicarboxylic Acid Metabolic Process
Small Molecule Metabolic Process
Glutamate Catabolic Process
Cellular Amino Acid Metabolic Process
Dicarboxylic Acid Catabolic Process
Neurotransmitter Biosynthetic Process
Response To Nutrient
Neurotransmitter Secretion
Response To Arsenic-containing Substance
Alpha-amino Acid Metabolic Process
Neurotransmitter Metabolic Process
Cellular Metabolic Process
Cellular Amino Acid Biosynthetic Process
Response To Drug
Regulation Of Neurotransmitter Levels
Fatty Acid Metabolic Process
Monocarboxylic Acid Metabolic Process
Ornithine Biosynthetic Process
Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism
Succinyl-CoA Pathway
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Establishment Of Blood-brain Barrier
L-methylmalonyl-CoA Metabolic Process
Dibenzo-p-dioxin Catabolic Process
Cofactor Metabolic Process
Neurotransmitter Transport
Establishment Of Localization In Cell
Porphyrin-containing Compound Metabolic Process
Valyl-tRNA Aminoacylation
Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity
Protein-pyridoxal-5-phosphate Linkage
Uroporphyrinogen III Biosynthetic Process
Negative Regulation Of Interleukin-1 Beta Secretion
Regulation Of Establishment Of Blood-brain Barrier
Tagcloud
?
author
bio
chance
chip
chosen
cyclin
d1
discover
egfr
epithelium
her2
ihc
insure
makes
manners
next
partner
pc3
performance
plasmid
plays
prostate
regulated
relationship
stream
traditional
transduction
transfection
whether
Tagcloud (Difference)
?
author
bio
chance
chip
chosen
cyclin
d1
discover
egfr
epithelium
her2
ihc
insure
makes
manners
next
partner
pc3
performance
plasmid
plays
prostate
regulated
relationship
stream
traditional
transduction
transfection
whether
Tagcloud (Intersection)
?