TRIM54 and SENP3

Number of citations of the paper that reports this interaction (PMID 22626734)
2

Data Source:
BioGRID (enzymatic study)

		TRIM54	SENP3
Gene Name		tripartite motif containing 54	SUMO1/sentrin/SMT3 specific peptidase 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Microtubule Associated Complex Z Disc	Nucleus Nucleolus Cytoplasm MLL1 Complex
	Molecular Function	Signal Transducer Activity Microtubule Binding Zinc Ion Binding	Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organismal Development Cell Differentiation	Proteolysis
Pathways
Drugs
Diseases
GWAS			IgM levels ( 23118916)
Protein-Protein Interactions		127 interactors: ADCY4 ALS2CR11 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC67 CCDC87 CDK18 CDKN1A CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM STRA13 TBC1D22B TCEA2 TCEB3 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D3 UBE2I UBE2U UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 WDYHV1 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587	13 interactors: ATF7IP CDK4 CDK6 EP300 HIC1 MDM2 NPM1 PARP1 SUMO2 TRIM54 TRIM63 USP15 USP21
Entrez ID		57159	26168
HPRD ID		05928	08339
Ensembl ID		ENSG00000138100	ENSG00000161956
Uniprot IDs		Q9BYV2	Q9H4L4
PDB IDs		3Q1D
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Organization Regulation Of Protein Catabolic Process Protein Metabolic Process Histone Deubiquitination RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Process Monoubiquitinated Protein Deubiquitination Histone Modification Gene Expression RNA Biosynthetic Process Chromatin Modification Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromatin Organization Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Chromosome Organization Cellular Response To Heat Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process	Positive Regulation Of Gene Expression Chromosome Organization Chromatin Organization Regulation Of Gene Expression Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Regulation Of Protein Catabolic Process Histone Deubiquitination Negative Regulation Of Cell Cycle Arrest Cellular Response To DNA Damage Stimulus Regulation Of Protein Metabolic Process Response To Organic Cyclic Compound Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cell Cycle Signaling Cellular Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Cycle Cell Communication Response To Steroid Hormone Response To Hormone Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Cellular Process Response To Organic Substance Cell Cycle Process Proteolysis Involved In Cellular Protein Catabolic Process Viral Process Negative Regulation Of Transcription, DNA-templated Cellular Protein Catabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Cellular Response To Organic Substance Protein Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Cellular Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stimulus Peptidyl-lysine Modification Proteasomal Protein Catabolic Process
Tagcloud ?			adaptive allowing cathepsin conjugation cytochrome degraded deprivation desumoylation determinants drp1 extreme facilitates fate fission gtpase ischaemia modifier ogd perk prolongs protects recover reoxygenation rnai sumo sumoylation suppresses unfolded upr
Tagcloud (Difference) ?			adaptive allowing cathepsin conjugation cytochrome degraded deprivation desumoylation determinants drp1 extreme facilitates fate fission gtpase ischaemia modifier ogd perk prolongs protects recover reoxygenation rnai sumo sumoylation suppresses unfolded upr
Tagcloud (Intersection) ?