TRIM54 and MCM7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM54	MCM7
Gene Name		tripartite motif containing 54	minichromosome maintenance complex component 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule Microtubule Associated Complex Z Disc	Chromatin Nucleoplasm Cytoplasm Cytosol Membrane MCM Complex
	Molecular Function	Signal Transducer Activity Microtubule Binding Zinc Ion Binding	DNA Binding Single-stranded DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding
	Biological Process	Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organismal Development Cell Differentiation	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus Cell Proliferation Regulation Of Phosphorylation Response To Drug Cellular Response To Epidermal Growth Factor Stimulus
Pathways			Synthesis of DNA G2/M Checkpoints Activation of the pre-replicative complex DNA Replication Pre-Initiation M/G1 Transition Regulation of DNA replication Activation of the pre-replicative complex Orc1 removal from chromatin S Phase DNA strand elongation Cell Cycle, Mitotic Assembly of the pre-replicative complex Orc1 removal from chromatin G1/S Transition Activation of ATR in response to replication stress Cell Cycle Checkpoints Removal of licensing factors from origins Mitotic G1-G1/S phases Switching of origins to a post-replicative state Unwinding of DNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		127 interactors: ADCY4 ALS2CR11 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC67 CCDC87 CDK18 CDKN1A CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM STRA13 TBC1D22B TCEA2 TCEB3 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D3 UBE2I UBE2U UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 WDYHV1 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587	59 interactors: AK8 APP ASB8 C8orf34 CCDC102B CCND1 CCNH CDC45 CDC6 CDC7 CDK7 CDKN1B CDT1 CRLS1 DBF4 FHL2 GOLGA2 HIF1A HIST3H3 IKBKG INTS6 KIFC3 MBIP MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM8 MCMBP MIPOL1 MNAT1 NAB2 NFKBIA ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PLK1 PNMA1 RAD17 RB1 RBL1 RBL2 RBM8A RPA1 SMC1A SNTA1 SP2 TCEB1 TREX1 TRIM27 TRIM54 UBE3A UBQLN1 USHBP1
Entrez ID		57159	4176
HPRD ID		05928	01154
Ensembl ID		ENSG00000138100	ENSG00000166508
Uniprot IDs		Q9BYV2	C6EMX8 P33993
PDB IDs		3Q1D
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Organization Regulation Of Protein Catabolic Process Protein Metabolic Process Histone Deubiquitination RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Process Monoubiquitinated Protein Deubiquitination Histone Modification Gene Expression RNA Biosynthetic Process Chromatin Modification Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromatin Organization Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Chromosome Organization Cellular Response To Heat Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Mitotic Cell Cycle Process DNA Replication Cell Cycle Cell Cycle Process DNA-dependent DNA Replication DNA Replication Initiation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mitotic Cell Cycle Phase Transition Cellular Metabolic Process Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cellular Response To DNA Damage Stimulus Cellular Response To Stress Chromosome Organization Regulation Of Kinase Activity Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Replication Checkpoint Positive Regulation Of Mitotic Cell Cycle DNA Duplex Unwinding DNA Geometric Change Regulation Of Phosphorylation Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Regulation Of Protein Kinase Activity Nucleotide-excision Repair, DNA Damage Removal Regulation Of Phosphorus Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Intracellular Receptor Signaling Pathway Metabolic Process
Tagcloud ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?			aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?