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SPG21 and TRIM9
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPG21
TRIM9
Gene Name
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
tripartite motif containing 9
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Cytoplasm
Cytoskeleton
Synaptic Vesicle
Cell Junction
Dendrite
Molecular Function
Protein Binding
CD4 Receptor Binding
SNARE Binding
Ubiquitin-protein Transferase Activity
Zinc Ion Binding
Ligase Activity
Protein Homodimerization Activity
Biological Process
Antigen Receptor-mediated Signaling Pathway
Synaptic Vesicle Exocytosis
Protein Ubiquitination
Negative Regulation Of SNARE Complex Assembly
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Calcium Ion-dependent Exocytosis
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
28 interactors:
AP3M1
BTRC
CHFR
CSNK1D
CWF19L2
DTNBP1
DTX3L
EVL
EXOC1
GFM2
LONRF1
MDM2
MNAT1
MUL1
NCF1
NFKBID
PCGF3
RNF166
RPL4P5
SNAP25
SPG21
TRIM27
TRIM46
TRIM8
TSSK3
USP2
USP21
VASP
Entrez ID
51324
114088
HPRD ID
10492
05947
Ensembl ID
ENSG00000090487
ENSG00000100505
Uniprot IDs
Q9NZD8
Q9C026
PDB IDs
2DB8
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Protein Ubiquitination
Regulation Of Proteasomal Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Organelle Organization
Regulation Of Protein Stability
Cellular Protein Metabolic Process
Cellular Protein Modification Process
Regulation Of Protein Catabolic Process
Regulation Of Proteolysis
Regulation Of Viral Transcription
Protein Complex Assembly
Protein Metabolic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Viral Release From Host Cell
Regulation Of Circadian Rhythm
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Positive Regulation Of Actin Filament Polymerization
Cellular Macromolecule Catabolic Process
Synaptic Vesicle Transport
Anterograde Synaptic Vesicle Transport
Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Viral Transcription
Positive Regulation Of Proteolysis
Regulation Of Viral Release From Host Cell
Cellular Protein Catabolic Process
Positive Regulation Of Protein Polymerization
G2/M Transition Of Mitotic Cell Cycle
Protein Destabilization
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Catabolic Process
Anterograde Axon Cargo Transport
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Viral Process
Mitotic Cell Cycle Process
Regulation Of Cellular Protein Metabolic Process
Protein Polyubiquitination
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of Organelle Organization
Circadian Rhythm
Regulation Of Actin Filament Polymerization
Organelle Localization
Mitotic Cell Cycle
Cellular Response To UV-C
Cellular Response To Vitamin B1
Posttranscriptional Regulation Of Gene Expression
Regulation Of Protein Metabolic Process
Positive Regulation Of Cytoskeleton Organization
Establishment Of Vesicle Localization
Tagcloud
?
alteration
alterations
arf
cadps2
frequently
gain
genomic
hot
ink4a
instability
mutants
mutation
mutations
obvious
p16
p53
piwil4
point
prepared
reason
restraining
resulting
saos
specificity
spot
suppresses
suppressor
transcriptional
tumors
Tagcloud (Difference)
?
alteration
alterations
arf
cadps2
frequently
gain
genomic
hot
ink4a
instability
mutants
mutation
mutations
obvious
p16
p53
piwil4
point
prepared
reason
restraining
resulting
saos
specificity
spot
suppresses
suppressor
transcriptional
tumors
Tagcloud (Intersection)
?