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TRIM54 and TRIM63
Number of citations of the paper that reports this interaction (PMID
11243782
)
63
Data Source:
BioGRID
(two hybrid, pull down)
HPRD
(two hybrid, in vitro)
TRIM54
TRIM63
Gene Name
tripartite motif containing 54
tripartite motif containing 63, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations
Cellular Component
Microtubule
Microtubule Associated Complex
Z Disc
Nucleus
Cytoplasm
Microtubule
Z Disc
M Band
Molecular Function
Signal Transducer Activity
Microtubule Binding
Zinc Ion Binding
Ubiquitin-protein Transferase Activity
Signal Transducer Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Titin Binding
Biological Process
Microtubule-based Process
Negative Regulation Of Microtubule Depolymerization
Signal Transduction
Multicellular Organismal Development
Cell Differentiation
Muscle Contraction
Signal Transduction
Regulation Of Gene Expression
Skeletal Muscle Atrophy
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To Interleukin-1
Cellular Response To Dexamethasone Stimulus
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
127 interactors:
ADCY4
ALS2CR11
ARFIP2
ARHGEF5
ATXN3
ATXN3L
ATXN7
BYSL
C12orf49
C1orf109
C1orf216
C1QTNF2
CALM3
CARD9
CCDC102B
CCDC146
CCDC28A
CCDC67
CCDC87
CDK18
CDKN1A
CEP57L1
CHCHD2
CKM
CRADD
CWF19L2
CYTH4
DCUN1D1
DNAL4
DTX2
EHHADH
EIF4E2
ELMO1
ENKD1
EPM2AIP1
EXOSC5
FAM110A
FAM124A
FAM124B
FAM161A
FARS2
FBF1
FLNC
GEM
GMCL1
GTF2IRD2
HAUS1
ING3
INPP5J
IQUB
JOSD1
KDM1A
KIFC3
KLHL38
KPNA2
KRT6A
KRT6B
KRT6C
LENG1
LIN37
LMO2
LNX1
LSM2
MAPK3
MBD3
MCM7
MEAF6
MFAP1
MID2
MYO5B
NGLY1
OSTF1
OTUB1
OTUB2
PIK3R3
PPP1R18
PRF1
RABGEF1
RAD23A
RBM41
RCOR3
RSRC2
SCNM1
SDCBP
SENP3
SH2D1B
SMARCE1
SNF8
SPG21
SSX2IP
STAM
STRA13
TBC1D22B
TCEA2
TCEB3
THOC1
TRIM55
TRIM63
TSHZ3
TTC23
UBE2D3
UBE2I
UBE2U
UCHL1
UCHL3
UCHL5
USHBP1
USP15
USP18
USP2
USP21
USP33
USP4
USP5
USP7
USP8
UTP14C
VPS28
WDR34
WDYHV1
YOD1
ZBTB16
ZGPAT
ZNF250
ZNF417
ZNF572
ZNF587
87 interactors:
ACTA1
AK1
AKR7A2
ALDOA
ANKRD1
APP
ATP5B
ATXN3
ATXN3L
BAP1
CKB
CKM
DCAF6
DES
EEF1G
EHHADH
EIF3E
ENO3
ESPL1
FHL2
FLNC
GFM1
GMEB1
HIBADH
JOSD1
LMCD1
MRPL19
MRPL41
MYBPC1
MYBPC3
MYL2
MYOT
MYOZ1
NDUFA1
NEB
NEBL
NOMO1
NRAP
OTUB1
OTUB2
PDHB
PDK4
PIAS1
PIAS2
PIAS3
PKM
PSMD4
PYGM
SENP2
SENP3
SQSTM1
SRF
STAM
SUMO2
TCAP
TNNC1
TNNI1
TNNI2
TNNI3
TNNT1
TNNT3
TRIM54
TRIM55
TTN
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2I
UBE2J1
UBE2U
UCHL1
UCHL3
UCHL5
UQCRC1
USP13
USP15
USP2
USP21
USP28
USP33
USP4
USP5
USP7
USP8
UXT
YOD1
Entrez ID
57159
84676
HPRD ID
05928
05843
Ensembl ID
ENSG00000138100
ENSG00000158022
Uniprot IDs
Q9BYV2
B4DN95
Q969Q1
PDB IDs
3Q1D
2D8U
3DDT
Enriched GO Terms of Interacting Partners
?
Protein Deubiquitination
Protein Modification By Small Protein Removal
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein Catabolic Process
Cellular Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Protein K63-linked Deubiquitination
Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Cellular Protein Metabolic Process
Regulation Of Metabolic Process
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Organelle Organization
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Histone Deubiquitination
RNA Metabolic Process
Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Cellular Process
Monoubiquitinated Protein Deubiquitination
Histone Modification
Gene Expression
RNA Biosynthetic Process
Chromatin Modification
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Proteolysis
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Chromatin Organization
Cellular Response To DNA Damage Stimulus
Nitrogen Compound Metabolic Process
Chromosome Organization
Cellular Response To Heat
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Protein Modification By Small Protein Removal
Muscle Filament Sliding
Actin-myosin Filament Sliding
Protein Deubiquitination
Actin-mediated Cell Contraction
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Actin Filament-based Movement
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K48-linked Deubiquitination
Proteolysis
Muscle Contraction
Regulation Of Proteasomal Protein Catabolic Process
Catabolic Process
Muscle System Process
Regulation Of Protein Catabolic Process
Actin Filament-based Process
Protein K63-linked Deubiquitination
Striated Muscle Cell Development
Striated Muscle Contraction
Muscle Cell Development
Muscle Structure Development
Myofibril Assembly
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Regulation Of Proteolysis
Cardiac Muscle Tissue Morphogenesis
Striated Muscle Cell Differentiation
Muscle Tissue Morphogenesis
Cardiac Muscle Tissue Development
Muscle Organ Morphogenesis
Actomyosin Structure Organization
Protein Sumoylation
Protein Metabolic Process
Striated Muscle Tissue Development
Muscle Cell Differentiation
Muscle Tissue Development
Regulation Of Muscle Contraction
Protein Modification By Small Protein Conjugation
Muscle Organ Development
Heart Morphogenesis
Regulation Of Cellular Protein Metabolic Process
Cardiac Myofibril Assembly
Muscle Fiber Development
Monoubiquitinated Protein Deubiquitination
Tagcloud
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Difference)
?
benzylic
bioactivation
clues
covalent
danger
dapk1
hapten
hepatotoxicity
il22
inflammasome
marks
methide
nevirapine
nlrp3
nvp
obligate
oh
oxidized
presumably
quinone
ra2
rash
rashes
reflecting
s100a7
s100a7a
sulfate
travels
Tagcloud (Intersection)
?