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SPG21 and RABAC1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
SPG21
RABAC1
Gene Name
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
Rab acceptor 1 (prenylated)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Golgi Apparatus
Plasma Membrane
Synaptic Vesicle
Membrane
Integral Component Of Membrane
Cell Junction
Molecular Function
Protein Binding
CD4 Receptor Binding
Protein Binding
Protein C-terminus Binding
Identical Protein Binding
Proline-rich Region Binding
Biological Process
Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
63 interactors:
ADCK3
CMTM3
CREB3
DUSP12
FAM160A2
FXR2
GDI1
HRAS
HRG
LNX1
MAD2L1
MCF2L
MIEF2
NAT14
NDRG4
NIF3L1
NR3C2
NUDT18
PBX3
PLEKHF2
PLK1
RAB17
RAB1A
RAB22A
RAB33A
RAB3A
RAB4A
RAB4B
RAB5A
RAB5B
RAB5C
RAB6A
RAB7A
RAP1A
RASD2
REEP5
RGS2
RHEB
RHOA
RIC8A
RIMS2
RIN3
RPS20
RRAS2
SGK1
SNCA
SNX1
SNX10
SNX11
SNX15
SPG21
SYT16
TNIP1
TRIM32
TSHR
TUBB2A
TXN2
VAMP2
VIM
VTA1
WDYHV1
WIPI2
ZFYVE21
Entrez ID
51324
10567
HPRD ID
10492
05375
Ensembl ID
ENSG00000090487
ENSG00000105404
Uniprot IDs
Q9NZD8
Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Ras Protein Signal Transduction
Rab Protein Signal Transduction
Small GTPase Mediated Signal Transduction
Establishment Of Protein Localization
Protein Transport
Protein Localization
Cellular Protein Localization
Cellular Localization
Intracellular Protein Transport
Regulation Of Cellular Component Organization
Regulation Of Vesicle-mediated Transport
Vesicle-mediated Transport
Establishment Of Localization In Cell
Intracellular Transport
Intracellular Signal Transduction
Endosomal Transport
Regulation Of Exocytosis
Transport
Cellular Response To Stimulus
Cell Communication
Regulation Of Endocytosis
Endocytosis
Regulation Of Locomotion
Vesicle Organization
Endosome Organization
Response To Stimulus
Regulation Of Synaptic Vesicle Transport
Regulation Of Cell Projection Organization
Signaling
Signal Transduction
Cytoplasmic Transport
Establishment Of Vesicle Localization
Regulation Of Neuronal Synaptic Plasticity
Vesicle Localization
Regulation Of Organelle Organization
Regulation Of Cell Migration
Positive Regulation Of Metabolic Process
Early Endosome To Late Endosome Transport
Regulation Of Neurotransmitter Secretion
Regulation Of Cell Motility
Regulation Of Signaling
Regulation Of Cellular Localization
Regulation Of Cellular Component Movement
Regulation Of Cellular Process
Regulation Of Synaptic Plasticity
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Transport
Synaptic Vesicle Recycling
Endomembrane System Organization
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Tagcloud (Difference)
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Tagcloud (Intersection)
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