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SH3RF1 and RACGAP1
Number of citations of the paper that reports this interaction (PMID
9482736
)
44
Data Source:
HPRD
(in vitro)
SH3RF1
RACGAP1
Gene Name
SH3 domain containing ring finger 1
Rac GTPase activating protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Apparatus
Cytosol
Lamellipodium
Perinuclear Region Of Cytoplasm
Acrosomal Vesicle
Nucleus
Nucleoplasm
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Vesicular Exosome
Mitotic Spindle
Centralspindlin Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Ligase Activity
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
Biological Process
Protein Ubiquitination
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of JNK Cascade
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Microtubule-based Movement
Cytokinesis, Initiation Of Separation
Small GTPase Mediated Signal Transduction
Spermatogenesis
Neuroblast Proliferation
Blood Coagulation
Sulfate Transport
Embryo Development
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
MHC class II antigen presentation
Kinesins
Factors involved in megakaryocyte development and platelet production
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
ADAM15
AKT1
AKT2
KCNJ1
MAP3K10
MAP3K11
MAP3K12
MAP3K9
MAP4K3
PAK2
PDCD6IP
RAC1
RACGAP1
SEMA6A
SIAH1
UBE2D1
UBE2D3
UBE2N
26 interactors:
AURKB
CDK1
CHN2
ECT2
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PPP2CA
PPP2R4
PPP2R5E
PRC1
PRSS23
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
Entrez ID
57630
29127
HPRD ID
15335
05402
Ensembl ID
ENSG00000154447
ENSG00000161800
Uniprot IDs
Q7Z6J0
B2RE34
Q9H0H5
PDB IDs
2OVJ
4B6D
Enriched GO Terms of Interacting Partners
?
Cell Death
Death
Positive Regulation Of Transferase Activity
Positive Regulation Of Protein Modification Process
Apoptotic Process
Programmed Cell Death
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Metabolic Process
JNK Cascade
Protein Autophosphorylation
Signaling
Regulation Of Catalytic Activity
Intracellular Signal Transduction
Cell Communication
Activation Of JNKK Activity
Positive Regulation Of Protein Phosphorylation
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Kinase Activity
Signal Transduction By Phosphorylation
Response To Stress
Signal Transduction
Positive Regulation Of Phosphorylation
Positive Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Activation Of MAPKK Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Phosphorylation
Cellular Response To Stress
MAPK Cascade
Regulation Of Signal Transduction
Positive Regulation Of Protein Kinase Activity
Immune Response-regulating Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Innate Immune Response
Cellular Response To Stimulus
Protein Metabolic Process
Peptidyl-serine Phosphorylation
Regulation Of Phosphorylation
Protein Phosphorylation
Regulation Of Signaling
Regulation Of Organelle Organization
Activation Of MAPKK Activity
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Cell Cycle
Cell Cycle Process
Mitotic Spindle Elongation
Intracellular Signal Transduction
Mitotic Spindle Organization
Regulation Of Catalytic Activity
Spindle Organization
Microtubule Cytoskeleton Organization
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Regulation Of Protein Kinase Activity
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Kinase Activity
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Catalytic Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Cell Death
Regulation Of MAPK Cascade
Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Modification Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cytokinesis
MAPK Cascade
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Phosphorylation
Apoptotic Process
Regulation Of Intracellular Signal Transduction
Programmed Cell Death
Protein Complex Assembly
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cytokinesis
Regulation Of Signal Transduction
G2/M Transition Of Mitotic Cell Cycle
Cell Death
Death
Regulation Of Protein Phosphorylation
Microtubule-based Process
Signal Transduction By Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Dephosphorylation
Tagcloud
?
anapc1
antagonizes
canonical
cd40l
cdk6
chip
combine
consequence
crosstalk
dek
ezh2
ikkalpha
involves
kappab2
lymphocytic
microenvironment
nemo
nik
p100
p21waf1
p52
polycomb
psma5
rel
rela
relb
retinoblastoma
route
senescent
Tagcloud (Difference)
?
anapc1
antagonizes
canonical
cd40l
cdk6
chip
combine
consequence
crosstalk
dek
ezh2
ikkalpha
involves
kappab2
lymphocytic
microenvironment
nemo
nik
p100
p21waf1
p52
polycomb
psma5
rel
rela
relb
retinoblastoma
route
senescent
Tagcloud (Intersection)
?