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SH3RF1 and MAP3K11
Number of citations of the paper that reports this interaction (PMID
14504284
)
16
Data Source:
HPRD
(in vivo)
SH3RF1
MAP3K11
Gene Name
SH3 domain containing ring finger 1
mitogen-activated protein kinase kinase kinase 11
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Apparatus
Cytosol
Lamellipodium
Perinuclear Region Of Cytoplasm
Cytoplasm
Centrosome
Microtubule
Membrane
Molecular Function
Protein Binding
Zinc Ion Binding
Ligase Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
JUN Kinase Kinase Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Mitogen-activated Protein Kinase Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Rac GTPase Binding
Biological Process
Protein Ubiquitination
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of JNK Cascade
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Activation Of MAPK Activity
Protein Phosphorylation
Microtubule-based Process
JNK Cascade
Activation Of JNKK Activity
Activation Of JUN Kinase Activity
Cell Death
Cell Proliferation
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of JNK Cascade
Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
ADAM15
AKT1
AKT2
KCNJ1
MAP3K10
MAP3K11
MAP3K12
MAP3K9
MAP4K3
PAK2
PDCD6IP
RAC1
RACGAP1
SEMA6A
SIAH1
UBE2D1
UBE2D3
UBE2N
27 interactors:
AKT1
APP
CDC42
CHUK
CLEC4G
COPS5
EPS8
IKBKB
KIF17
KIF3A
KIF3B
KIFAP3
MAP2K4
MAP2K7
MAP3K12
MAP4K1
MAP4K2
MAPK8IP1
MAPK8IP2
MAPK8IP3
PIN1
RAC1
RHOG
SH3RF1
STUB1
TRAF6
UBC
Entrez ID
57630
4296
HPRD ID
15335
02502
Ensembl ID
ENSG00000154447
ENSG00000173327
Uniprot IDs
Q7Z6J0
Q16584
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Death
Death
Positive Regulation Of Transferase Activity
Positive Regulation Of Protein Modification Process
Apoptotic Process
Programmed Cell Death
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Metabolic Process
JNK Cascade
Protein Autophosphorylation
Signaling
Regulation Of Catalytic Activity
Intracellular Signal Transduction
Cell Communication
Activation Of JNKK Activity
Positive Regulation Of Protein Phosphorylation
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Kinase Activity
Signal Transduction By Phosphorylation
Response To Stress
Signal Transduction
Positive Regulation Of Phosphorylation
Positive Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Activation Of MAPKK Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Cellular Protein Modification Process
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Phosphorylation
Cellular Response To Stress
MAPK Cascade
Regulation Of Signal Transduction
Positive Regulation Of Protein Kinase Activity
Immune Response-regulating Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of Intracellular Signal Transduction
Innate Immune Response
Cellular Response To Stimulus
Protein Metabolic Process
Peptidyl-serine Phosphorylation
Regulation Of Phosphorylation
Protein Phosphorylation
Regulation Of Signaling
Regulation Of Organelle Organization
Regulation Of JNK Cascade
Regulation Of Stress-activated MAPK Cascade
JNK Cascade
Regulation Of MAPK Cascade
Regulation Of Signal Transduction
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Transferase Activity
Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Regulation Of Phosphorylation
Response To Stress
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Kinase Activity
MAPK Cascade
Regulation Of Protein Phosphorylation
Positive Regulation Of Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Kinase Activity
Signal Transduction By Phosphorylation
Positive Regulation Of Protein Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of Catalytic Activity
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Phosphorylation
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Protein Metabolic Process
Regulation Of JUN Kinase Activity
Fc Receptor Signaling Pathway
Innate Immune Response
Positive Regulation Of MAPK Cascade
Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Positive Regulation Of Metabolic Process
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Immune System Process
Toll-like Receptor 2 Signaling Pathway
Positive Regulation Of JNK Cascade
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud
?
acceleration
activate
agar
besides
carcinogenesis
cdk2
colony
crkl
cycle
cycling1
facilitate
g1
htert
mb
mda
methylate
methyltransferase
mynd
oncogenes
phenotypes
pik3cb
riz
set
smyd3
soft
stat1
transduction
transformed
wnt10b
Tagcloud (Difference)
?
acceleration
activate
agar
besides
carcinogenesis
cdk2
colony
crkl
cycle
cycling1
facilitate
g1
htert
mb
mda
methylate
methyltransferase
mynd
oncogenes
phenotypes
pik3cb
riz
set
smyd3
soft
stat1
transduction
transformed
wnt10b
Tagcloud (Intersection)
?