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RACGAP1 and MPRIP
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
RACGAP1
MPRIP
Gene Name
Rac GTPase activating protein 1
myosin phosphatase Rho interacting protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Vesicular Exosome
Mitotic Spindle
Centralspindlin Complex
Cytoplasm
Focal Adhesion
Actin Cytoskeleton
Molecular Function
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
Actin Binding
Protein Binding
Biological Process
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Microtubule-based Movement
Cytokinesis, Initiation Of Separation
Small GTPase Mediated Signal Transduction
Spermatogenesis
Neuroblast Proliferation
Blood Coagulation
Sulfate Transport
Embryo Development
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
MHC class II antigen presentation
Kinesins
Factors involved in megakaryocyte development and platelet production
Adaptive Immune System
Drugs
Diseases
GWAS
Diabetic retinopathy (
21441570
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
26 interactors:
AURKB
CDK1
CHN2
ECT2
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PPP2CA
PPP2R4
PPP2R5E
PRC1
PRSS23
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
13 interactors:
ATXN7
IKBKG
LSM8
NOS3
PIAS4
PPP1R12A
PPP1R12C
RACGAP1
RHOA
YTHDC1
YWHAB
YWHAG
YWHAQ
Entrez ID
29127
23164
HPRD ID
05402
17591
Ensembl ID
ENSG00000161800
ENSG00000133030
Uniprot IDs
B2RE34
Q9H0H5
Q6WCQ1
Q8N236
PDB IDs
2OVJ
4B6D
Enriched GO Terms of Interacting Partners
?
Activation Of MAPKK Activity
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Cell Cycle
Cell Cycle Process
Mitotic Spindle Elongation
Intracellular Signal Transduction
Mitotic Spindle Organization
Regulation Of Catalytic Activity
Spindle Organization
Microtubule Cytoskeleton Organization
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Regulation Of Protein Kinase Activity
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Kinase Activity
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Catalytic Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Cell Death
Regulation Of MAPK Cascade
Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Modification Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cytokinesis
MAPK Cascade
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Phosphorylation
Apoptotic Process
Regulation Of Intracellular Signal Transduction
Programmed Cell Death
Protein Complex Assembly
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cytokinesis
Regulation Of Signal Transduction
G2/M Transition Of Mitotic Cell Cycle
Cell Death
Death
Regulation Of Protein Phosphorylation
Microtubule-based Process
Signal Transduction By Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Dephosphorylation
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Signal Transduction
Regulation Of Intracellular Transport
Regulation Of Signaling
Positive Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Intracellular Transport
Regulation Of Cellular Localization
Intracellular Signal Transduction
Regulation Of Mitochondrion Organization
Positive Regulation Of Signal Transduction
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Protein Localization
Regulation Of Apoptotic Process
Positive Regulation Of Organelle Organization
Regulation Of Phosphorus Metabolic Process
Mitotic Spindle Assembly
Regulation Of Cell Death
Regulation Of Organelle Organization
Microtubule Cytoskeleton Organization
Intrinsic Apoptotic Signaling Pathway
Signal Transduction
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Substantia Nigra Development
Positive Regulation Of Cytokinesis
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Death
Mitotic Spindle Organization
Signaling
Regulation Of Establishment Of Protein Localization
Negative Regulation Of Cellular Metabolic Process
Mitotic Cell Cycle Process
Cell Communication
Neural Nucleus Development
Positive Regulation Of Transport
Mitotic Cell Cycle
Regulation Of Cytokinesis
Microtubule-based Process
Mitotic Nuclear Division
Positive Regulation Of Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Cytokinesis, Initiation Of Separation
Actomyosin Contractile Ring Assembly
Regulation Of Catalytic Activity
Apoptotic Signaling Pathway
Spindle Assembly
Positive Regulation Of Cellular Metabolic Process
Tagcloud
?
anapc1
antagonizes
canonical
cd40l
cdk6
chip
combine
consequence
crosstalk
dek
ezh2
ikkalpha
involves
kappab2
lymphocytic
microenvironment
nemo
nik
p100
p21waf1
p52
polycomb
psma5
rel
rela
relb
retinoblastoma
route
senescent
Tagcloud (Difference)
?
anapc1
antagonizes
canonical
cd40l
cdk6
chip
combine
consequence
crosstalk
dek
ezh2
ikkalpha
involves
kappab2
lymphocytic
microenvironment
nemo
nik
p100
p21waf1
p52
polycomb
psma5
rel
rela
relb
retinoblastoma
route
senescent
Tagcloud (Intersection)
?