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RACGAP1 and TXNDC11
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
RACGAP1
TXNDC11
Gene Name
Rac GTPase activating protein 1
thioredoxin domain containing 11
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Acrosomal Vesicle
Nucleus
Nucleoplasm
Cytosol
Microtubule
Midbody
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Cleavage Furrow
Spindle Midzone
Extracellular Vesicular Exosome
Mitotic Spindle
Centralspindlin Complex
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
GTPase Activator Activity
Protein Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Microtubule Binding
Protein Kinase Binding
Alpha-tubulin Binding
Gamma-tubulin Binding
Metal Ion Binding
Beta-tubulin Binding
Protein Disulfide Isomerase Activity
Protein Binding
Biological Process
Mitotic Cytokinesis
Actomyosin Contractile Ring Assembly
Microtubule-based Movement
Cytokinesis, Initiation Of Separation
Small GTPase Mediated Signal Transduction
Spermatogenesis
Neuroblast Proliferation
Blood Coagulation
Sulfate Transport
Embryo Development
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Mitotic Spindle Midzone Assembly
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Protein Folding
Response To Endoplasmic Reticulum Stress
Cell Redox Homeostasis
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
MHC class II antigen presentation
Kinesins
Factors involved in megakaryocyte development and platelet production
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
AURKB
CDK1
CHN2
ECT2
KIF23
MAP3K10
MAP3K4
MORF4L1
MPRIP
NRAS
PPP2CA
PPP2R4
PPP2R5E
PRC1
PRSS23
RND2
SH3RF1
SLC16A10
SLC26A8
TANK
TUBA4A
TUBG1
TXNDC11
VAV1
YWHAB
YWHAG
17 interactors:
ACAA1
ATXN7
CDKN1A
DUOX1
DUOX2
GFI1B
HSP90B1
KRT15
KRT18
NOS3
ORC5
RACGAP1
RPS19
RPS6KA5
SOCS3
STAT5A
TPO
Entrez ID
29127
51061
HPRD ID
05402
07125
Ensembl ID
ENSG00000161800
ENSG00000153066
Uniprot IDs
B2RE34
Q9H0H5
Q6PKC3
PDB IDs
2OVJ
4B6D
Enriched GO Terms of Interacting Partners
?
Activation Of MAPKK Activity
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Cell Cycle
Cell Cycle Process
Mitotic Spindle Elongation
Intracellular Signal Transduction
Mitotic Spindle Organization
Regulation Of Catalytic Activity
Spindle Organization
Microtubule Cytoskeleton Organization
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Regulation Of Protein Kinase Activity
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Kinase Activity
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Transferase Activity
Positive Regulation Of Catalytic Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Cell Death
Regulation Of MAPK Cascade
Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Modification Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cytokinesis
MAPK Cascade
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Phosphorylation
Apoptotic Process
Regulation Of Intracellular Signal Transduction
Programmed Cell Death
Protein Complex Assembly
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cytokinesis
Regulation Of Signal Transduction
G2/M Transition Of Mitotic Cell Cycle
Cell Death
Death
Regulation Of Protein Phosphorylation
Microtubule-based Process
Signal Transduction By Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Dephosphorylation
Thyroid Hormone Generation
Hydrogen Peroxide Catabolic Process
Thyroid Hormone Metabolic Process
Cytokine-mediated Signaling Pathway
Regulation Of Innate Immune Response
Reactive Oxygen Species Metabolic Process
Anatomical Structure Development
Cuticle Development
Cellular Response To Organic Substance
Hydrogen Peroxide Metabolic Process
Cellular Response To Cytokine Stimulus
Developmental Process
Immune System Process
Response To Cytokine
Hormone Biosynthetic Process
Positive Regulation Of Innate Immune Response
Response To Organonitrogen Compound
Response To Organic Substance
Regulation Of Immune Response
Cellular Modified Amino Acid Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Phenol-containing Compound Metabolic Process
Negative Regulation Of Cell Death
Multicellular Organismal Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Catabolic Process
Growth Hormone Receptor Signaling Pathway
System Development
Response To Organophosphorus
Cellular Response To Growth Hormone Stimulus
Regulation Of Immune System Process
Response To Stress
Response To Purine-containing Compound
Hormone Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Response To Growth Hormone
Regulation Of Protein Metabolic Process
Regulation Of Cell Death
Organ Development
JAK-STAT Cascade
Cell Surface Receptor Signaling Pathway
Organelle Organization
Histone H2A-S1 Phosphorylation
Cytokinesis, Initiation Of Separation
Actomyosin Contractile Ring Assembly
Tagcloud
?
anapc1
antagonizes
canonical
cd40l
cdk6
chip
combine
consequence
crosstalk
dek
ezh2
ikkalpha
involves
kappab2
lymphocytic
microenvironment
nemo
nik
p100
p21waf1
p52
polycomb
psma5
rel
rela
relb
retinoblastoma
route
senescent
Tagcloud (Difference)
?
anapc1
antagonizes
canonical
cd40l
cdk6
chip
combine
consequence
crosstalk
dek
ezh2
ikkalpha
involves
kappab2
lymphocytic
microenvironment
nemo
nik
p100
p21waf1
p52
polycomb
psma5
rel
rela
relb
retinoblastoma
route
senescent
Tagcloud (Intersection)
?