SH3RF1 and MAP3K9

Number of citations of the paper that reports this interaction (PMID 14504284)
16

Data Source:
HPRD (in vitro)

		SH3RF1	MAP3K9
Gene Name		SH3 domain containing ring finger 1	mitogen-activated protein kinase kinase kinase 9
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Cytosol Lamellipodium Perinuclear Region Of Cytoplasm	Cellular_component
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity MAP Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of JNK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Activation Of JNKK Activity Activation Of JUN Kinase Activity Peptidyl-tyrosine Phosphorylation Positive Regulation Of Apoptotic Process Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS			Reasoning ( 21107309)
Protein-Protein Interactions		18 interactors: ADAM15 AKT1 AKT2 KCNJ1 MAP3K10 MAP3K11 MAP3K12 MAP3K9 MAP4K3 PAK2 PDCD6IP RAC1 RACGAP1 SEMA6A SIAH1 UBE2D1 UBE2D3 UBE2N	1 interactors: SH3RF1
Entrez ID		57630	4293
HPRD ID		15335	15965
Ensembl ID		ENSG00000154447	ENSG00000006432
Uniprot IDs		Q7Z6J0	G3V4P9 J3KPI6 P80192
PDB IDs			3DTC
Enriched GO Terms of Interacting Partners?		Cell Death Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Apoptotic Process Programmed Cell Death Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process JNK Cascade Protein Autophosphorylation Signaling Regulation Of Catalytic Activity Intracellular Signal Transduction Cell Communication Activation Of JNKK Activity Positive Regulation Of Protein Phosphorylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Kinase Activity Signal Transduction By Phosphorylation Response To Stress Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Activation Of MAPKK Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Cellular Response To Stress MAPK Cascade Regulation Of Signal Transduction Positive Regulation Of Protein Kinase Activity Immune Response-regulating Signaling Pathway Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Cellular Response To Stimulus Protein Metabolic Process Peptidyl-serine Phosphorylation Regulation Of Phosphorylation Protein Phosphorylation Regulation Of Signaling Regulation Of Organelle Organization
Tagcloud ?			3p 3q abcc5 agtr1 amplifications bcl6 beadarray beadarraytrade cdkn2a cdkn2b coincidently csf1 ctnnb1 dnas dvl3 esophageal fancd2 ffpe fgf12 hapmap il2 irf7 kiaa1804 mlf1 ntrk2 pms2 prkar1a tnfsf10 tnk2
Tagcloud (Difference) ?			3p 3q abcc5 agtr1 amplifications bcl6 beadarray beadarraytrade cdkn2a cdkn2b coincidently csf1 ctnnb1 dnas dvl3 esophageal fancd2 ffpe fgf12 hapmap il2 irf7 kiaa1804 mlf1 ntrk2 pms2 prkar1a tnfsf10 tnk2
Tagcloud (Intersection) ?