SH3RF1

Gene Name		SH3 domain containing ring finger 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Cytosol Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of JNK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		18 interactors: ADAM15 AKT1 AKT2 KCNJ1 MAP3K10 MAP3K11 MAP3K12 MAP3K9 MAP4K3 PAK2 PDCD6IP RAC1 RACGAP1 SEMA6A SIAH1 UBE2D1 UBE2D3 UBE2N
Entrez ID		57630
HPRD ID		15335
Ensembl ID		ENSG00000154447
Uniprot IDs		Q7Z6J0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Death Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Apoptotic Process Programmed Cell Death Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process JNK Cascade Protein Autophosphorylation Signaling Regulation Of Catalytic Activity Intracellular Signal Transduction Cell Communication Activation Of JNKK Activity Positive Regulation Of Protein Phosphorylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Kinase Activity Signal Transduction By Phosphorylation Response To Stress Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Activation Of MAPKK Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Cellular Response To Stress MAPK Cascade Regulation Of Signal Transduction Positive Regulation Of Protein Kinase Activity Immune Response-regulating Signaling Pathway Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Cellular Response To Stimulus Protein Metabolic Process Peptidyl-serine Phosphorylation Regulation Of Phosphorylation Protein Phosphorylation Regulation Of Signaling Regulation Of Organelle Organization
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