SH3RF1 and SEMA6A

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		SH3RF1	SEMA6A
Gene Name		SH3 domain containing ring finger 1	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Cytosol Lamellipodium Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane Axon
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Receptor Activity Protein Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of JNK Cascade Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Apoptotic Process Cytoskeleton Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Organ Morphogenesis
Pathways			Axon guidance Semaphorin interactions Other semaphorin interactions
Drugs
Diseases
GWAS			Allergic rhinitis ( 22036096) Amyotrophic lateral sclerosis ( 19451621) Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		18 interactors: ADAM15 AKT1 AKT2 KCNJ1 MAP3K10 MAP3K11 MAP3K12 MAP3K9 MAP4K3 PAK2 PDCD6IP RAC1 RACGAP1 SEMA6A SIAH1 UBE2D1 UBE2D3 UBE2N	6 interactors: EVL ITSN2 SH3RF1 SORBS1 SORBS2 SUMO1
Entrez ID		57630	57556
HPRD ID		15335	06906
Ensembl ID		ENSG00000154447	ENSG00000092421
Uniprot IDs		Q7Z6J0	Q9H2E6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Death Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Apoptotic Process Programmed Cell Death Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process JNK Cascade Protein Autophosphorylation Signaling Regulation Of Catalytic Activity Intracellular Signal Transduction Cell Communication Activation Of JNKK Activity Positive Regulation Of Protein Phosphorylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Kinase Activity Signal Transduction By Phosphorylation Response To Stress Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Activation Of MAPKK Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Cellular Response To Stress MAPK Cascade Regulation Of Signal Transduction Positive Regulation Of Protein Kinase Activity Immune Response-regulating Signaling Pathway Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Cellular Response To Stimulus Protein Metabolic Process Peptidyl-serine Phosphorylation Regulation Of Phosphorylation Protein Phosphorylation Regulation Of Signaling Regulation Of Organelle Organization	Actin Filament Organization Actin Cytoskeleton Organization Actin Filament-based Process Positive Regulation Of Protein Complex Assembly PML Body Organization Protein Localization To Nuclear Pore Protein Localization To Nuclear Envelope Negative Regulation Of Ruffle Assembly Cytoskeleton Organization
Tagcloud ?			bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 ncr3 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 srgn trem2 tubal3 txnrd1
Tagcloud (Difference) ?			bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 ncr3 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 srgn trem2 tubal3 txnrd1
Tagcloud (Intersection) ?