LUC7L and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		LUC7L	FBXO25
Gene Name		LUC7-like (S. cerevisiae)	F-box protein 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	U1 SnRNP	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding RS Domain Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	MRNA Splice Site Selection Negative Regulation Of Striated Muscle Tissue Development	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978)
Protein-Protein Interactions		11 interactors: CALM1 CHERP CTNNBL1 FAM173A FBXO25 GADD45G PRDX1 PRMT5 SRPK1 SRPK2 TCERG1	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		55692	26260
HPRD ID		08476	16439
Ensembl ID		ENSG00000007392	ENSG00000147364
Uniprot IDs		D3DU41 Q1W6G4 Q9NQ29	Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing Positive Regulation Of Viral Genome Replication MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Regulation Of Cell Cycle Positive Regulation Of Viral Process Nuclear Speck Organization Negative Regulation Of Viral Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Intracellular Transport RNA Metabolic Process Regulation Of RNA Splicing Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Reactive Oxygen Species Metabolic Process Immune System Process Nucleus Organization Gene Expression Immune Response Defense Response Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Cell Death Regulation Of Viral Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Ion Homeostasis Developmental Process Nitrogen Compound Metabolic Process Regulation Of Protein Import Into Nucleus Ribonucleoprotein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Stress-activated MAPK Cascade Cellular Metabolic Process Regulation Of Protein Localization To Nucleus Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Nucleocytoplasmic Transport Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Sperm Chromatin Condensation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Division	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
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