LUC7L and FAM173A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LUC7L	FAM173A
Gene Name		LUC7-like (S. cerevisiae)	family with sequence similarity 173, member A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	U1 SnRNP	Integral Component Of Membrane
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding RS Domain Binding
	Biological Process	MRNA Splice Site Selection Negative Regulation Of Striated Muscle Tissue Development
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978)
Protein-Protein Interactions		11 interactors: CALM1 CHERP CTNNBL1 FAM173A FBXO25 GADD45G PRDX1 PRMT5 SRPK1 SRPK2 TCERG1	9 interactors: BAG6 HAP1 IMMT KAT5 LUC7L LUC7L2 PFN2 SH3GL3 TP53
Entrez ID		55692	65990
HPRD ID		08476	14500
Ensembl ID		ENSG00000007392	ENSG00000103254
Uniprot IDs		D3DU41 Q1W6G4 Q9NQ29	J3KMW5 Q9BQD7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing Positive Regulation Of Viral Genome Replication MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Regulation Of Cell Cycle Positive Regulation Of Viral Process Nuclear Speck Organization Negative Regulation Of Viral Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Intracellular Transport RNA Metabolic Process Regulation Of RNA Splicing Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Reactive Oxygen Species Metabolic Process Immune System Process Nucleus Organization Gene Expression Immune Response Defense Response Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Cell Death Regulation Of Viral Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Ion Homeostasis Developmental Process Nitrogen Compound Metabolic Process Regulation Of Protein Import Into Nucleus Ribonucleoprotein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Stress-activated MAPK Cascade Cellular Metabolic Process Regulation Of Protein Localization To Nucleus Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Nucleocytoplasmic Transport Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Sperm Chromatin Condensation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Division	Signal Transduction By P53 Class Mediator DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Double-strand Break Repair Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator MRNA Splice Site Selection Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To DNA Damage Stimulus Positive Regulation Of Cellular Component Biogenesis Spliceosomal Complex Assembly Base-excision Repair Central Nervous System Development Chromosome Organization Positive Regulation Of Organelle Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Signal Transduction In Response To DNA Damage Nucleotide-excision Repair Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Protein Metabolic Process Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Cerebellum Development Regulation Of Cell Projection Assembly Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Metencephalon Development Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Acetylation Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cilium Assembly Negative Regulation Of Helicase Activity Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity DNA Repair Response To Ionizing Radiation Regulation Of Exocytosis Response To Endoplasmic Reticulum Stress Cellular Response To Stress Ribonucleoprotein Complex Assembly Hindbrain Development Positive Regulation Of Protein Complex Assembly Chromatin Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Ruffle Assembly Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cell Aging
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