TRIM9 and CHFR

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIM9	CHFR
Gene Name		tripartite motif containing 9	checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Synaptic Vesicle Cell Junction Dendrite	Nucleus PML Body
	Molecular Function	SNARE Binding Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Protein Homodimerization Activity	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Checkpoint Modification-dependent Protein Catabolic Process Cell Division
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 VASP	26 interactors: AURKA BRD4 CBLC EEF1G GABBR1 HDAC1 HDAC2 HIST2H2AC HIST2H2BE ITGAE PML RNF125 RNF7 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2N UBE2V1 UBE2W WDR47
Entrez ID		114088	55743
HPRD ID		05947	05552
Ensembl ID		ENSG00000100505	ENSG00000072609
Uniprot IDs		Q9C026	Q96EP1
PDB IDs		2DB8	1LGP 1LGQ 2XOC 2XOY 2XOZ 2XP0
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Organelle Organization Regulation Of Protein Stability Cellular Protein Metabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Viral Transcription Protein Complex Assembly Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Release From Host Cell Regulation Of Circadian Rhythm Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Actin Filament Polymerization Cellular Macromolecule Catabolic Process Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Viral Transcription Positive Regulation Of Proteolysis Regulation Of Viral Release From Host Cell Cellular Protein Catabolic Process Positive Regulation Of Protein Polymerization G2/M Transition Of Mitotic Cell Cycle Protein Destabilization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Catabolic Process Anterograde Axon Cargo Transport Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Viral Process Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Positive Regulation Of Organelle Organization Circadian Rhythm Regulation Of Actin Filament Polymerization Organelle Localization Mitotic Cell Cycle Cellular Response To UV-C Cellular Response To Vitamin B1 Posttranscriptional Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Cytoskeleton Organization Establishment Of Vesicle Localization	Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein K48-linked Ubiquitination Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Metabolic Process Protein Catabolic Process Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Cellular Response To Stress Proteolysis Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Cell Cycle Activation Of Innate Immune Response Catabolic Process Innate Immune Response Positive Regulation Of Innate Immune Response Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Stress Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Regulation Of Innate Immune Response Chromatin Organization Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of Response To DNA Damage Stimulus Protein Monoubiquitination Positive Regulation Of Proteolysis Transforming Growth Factor Beta Receptor Signaling Pathway ISG15-protein Conjugation Cellular Response To DNA Damage Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Fungiform Papilla Formation Regulation Of DNA-templated Transcription In Response To Stress Chromatin Modification Regulation Of Organelle Organization
Tagcloud ?		alteration alterations arf cadps2 frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional tumors	adeno adenocarcinoma adenocarcinomas alk atlas biomarker correlates datasets egfr erbb2 exon19 fgfr1 fgfr2 fgfr3 kras nf1 pik3ca powerful predictor project ret ros1 seq squamous stk11 taxane tcga tp53 utilized
Tagcloud (Difference) ?		alteration alterations arf cadps2 frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional tumors	adeno adenocarcinoma adenocarcinomas alk atlas biomarker correlates datasets egfr erbb2 exon19 fgfr1 fgfr2 fgfr3 kras nf1 pik3ca powerful predictor project ret ros1 seq squamous stk11 taxane tcga tp53 utilized
Tagcloud (Intersection) ?